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Victor Ambros, PhD

Research Focus - Genetic Control of Developmental Timing in C. elegans

  • Molecular basis of regulated cell fate transitions
  • Regulation of stem cell proliferation and self-renewal
  • Coordination of growth and cell fate across the animal
  • Regulation of mRNA translation by microRNAs and RNA binding proteins

Representative Publication

Nelson C, Ambros V. Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity. Development. 2019;146(5):dev172031.

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More Publications

In the News

Getting Results…
  • UMass Chan study shows how novel mechanism in P. aeruginosa bacteria disables ribosome
    Research News

    UMMS study shows how novel mechanism in P. aeruginosa bacteria disables ribosome

    A new study by Alejandro Vasquez-Rifo, PhD, and Victor Ambros, PhD, shows that certain strains of Pseudomonas aeruginosa, a rod-shaped bacterial pathogen that causes disease in plants and animals, including humans, have a unique mechanism for disabling and degrading the ribosome in its host cells.

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  • Victor Ambros named fellow of the American Association for the Advancement of Science
    Research News

    Victor Ambros named fellow of the American Association for the Advancement of Science

    Victor Ambros, PhD, has been elected by his peers as a fellow of the American Association for the Advancement of Science.

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