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Located in Worcester, Massachusetts, the UMass Cancer Center is committed to providing exceptional patient care, conducting cutting-edge research at the highest level, offering excellence in education and training, and serving as an educational resource and advocate for the Central Massachusetts community.
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Expert Cancer Care in Central Massachusetts

We offer comprehensive cancer care for all childhood and adult cancers, combining state-of-the-art treatments with compassionate support for patients and their families.
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Cutting-Edge Cancer Research

We carry out front-line research in basic, translational, clinical and population-based discovery to find newer, better methods for the prevention, detection, diagnosis, and treatment of cancer.
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Education

World Class Medical and Scientific Education

The UMass Cancer Center is dedicated to training the next generation of cancer researchers, clinicians and physician-scientists.
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Additional Resources

Sharon Cantor, PhD

Professor, Department of Molecular, Cell and Cancer Biology, UMass Chan Medical School

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Sharon Cantor, PhD

Research Focus - Defining Replication Stress and Therapy Response Outcomes Regulated by the Fanconi Anemia/BRCA Pathway

Characterizing replication stress responses mediated by the Fanconi Anemia/BRCA pathway
Defining pathogenic mutations in hereditary breast/ovarian cancer genes
Defining and targeting replication stress suppression pathways in cancer
Understanding the mechanisms of therapy response and resistance in cancer

Representative Publication

Panzarino NJ, Krais JJ, Cong K, et al. Replication gaps underlie BRCA deficiency and therapy response. Cancer Res. 2021;81(5):1388-1397.

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In the News

Getting Results…

Media, Research News

Communicating science: Sharon Cantor discusses drug resistance in breast, ovarian cancer

Research by Sharon Cantor, PhD, into how chemotherapy works in inherited breast and ovarian cancer overturned a long-held model in the field and will play a key role in developing successful therapies.

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Research News

Cantor lab rethinks how common chemotherapy drug used in breast and ovarian cancer works

Research from the lab of Sharon Cantor, PhD, provides a new understanding of a PARP inhibitor, a chemotherapy drug commonly used against breast and ovarian cancer.

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Education News, Media

For GSBS class speaker Sumeet Nayak science brings hope

Sumeet Nayak’s research in the lab of Sharon B. Cantor, PhD, has led to a renewed understanding of how cancer develops and has opened up avenues to effectively advance anti-cancer therapies.

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Research News

UMMS researchers forging new understanding of BRCA cancer gene function with NCI grant

A UMass Medical School research team has been awarded a National Cancer Institute grant to advance understanding of how hereditary breast and ovarian cancer genes work, and why tumors lacking these genes are sensitive to chemotherapy.

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