For the latest COVID-19 campus news and resources, visit umassmed.edu/coronavirus.

Search Close Search
Page Menu

Sharon Cantor, PhD

Research Focus - Defining Replication Stress and Therapy Response Outcomes Regulated by the Fanconi Anemia/BRCA Pathway

  • Characterizing replication stress responses mediated by the Fanconi Anemia/BRCA pathway
  • Defining pathogenic mutations in hereditary breast/ovarian cancer genes
  • Defining and targeting replication stress suppression pathways in cancer
  • Understanding the mechanisms of therapy response and resistance in cancer

Representative Publication

Panzarino NJ, Krais JJ, Cong K, et al. Replication gaps underlie BRCA deficiency and therapy response. Cancer Res. 2021;81(5):1388-1397.

Read Publication

More Publications

In the News

Getting Results…
  • Sharon Cantor and Andres Schanzer appointed to endowed chairs
    Community News

    Sharon Cantor and Andres Schanzer appointed to endowed chairs

    The University of Massachusetts Board of Trustees voted to approve one new endowed chair at UMass Chan Medical School and the appointment of two accomplished faculty members to endowed chairs.

    Read more
  • Communicating science: Sharon Cantor discusses drug resistance in breast, ovarian cancer
    Media, Research News

    Communicating science: Sharon Cantor discusses drug resistance in breast, ovarian cancer

    Research by Sharon Cantor, PhD, into how chemotherapy works in inherited breast and ovarian cancer overturned a long-held model in the field and will play a key role in developing successful therapies.

    Read more
  • Cantor lab rethinks how common chemotherapy drug used in breast and ovarian cancer works
    Research News

    Cantor lab rethinks how common chemotherapy drug used in breast and ovarian cancer works

    Research from the lab of Sharon Cantor, PhD, provides a new understanding of a PARP inhibitor, a chemotherapy drug commonly used against breast and ovarian cancer.

    Read more
  • For GSBS class speaker Sumeet Nayak science brings hope
    Education News, Media

    For GSBS class speaker Sumeet Nayak science brings hope

    Sumeet Nayak’s research in the lab of Sharon B. Cantor, PhD, has led to a renewed understanding of how cancer develops and has opened up avenues to effectively advance anti-cancer therapies.

    Read more
  • UMMS researchers forging new understanding of BRCA cancer gene function with NCI grant
    Research News

    UMMS researchers forging new understanding of BRCA cancer gene function with NCI grant

    A UMass Medical School research team has been awarded a National Cancer Institute grant to advance understanding of how hereditary breast and ovarian cancer genes work, and why tumors lacking these genes are sensitive to chemotherapy.

    Read more