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Richard I. Gregory, PhD

Research Focus - Role of the Epitranscriptome in Cancer

  • Characterizing the RNA modification landscape in human tumors
  • Identifying RNA-modifying enzymes relevant to cancer as potential new therapeutic targets
  • Characterizing human tRNA genes and translational remodeling in cancer biology
  • Exploring codon-biased mRNA translation in cancer biology and drug sensitivity

Representative Publication

Orellana, E.A., Liu, Q., Yankova, e. et al. METTL1-mediated m7G modification of Arg-TCT tRNA drives oncogenic transformation. Mol. Cell. 81, 3323–3338 (2021). 

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UMass Chan News Highlights

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  • UMass Chan leads new $4.4 million study to study melanoma

    UMass Chan leads new $4.4 million study to study melanoma

    UMass Chan Medical School received a five-year, $4.4 million National Cancer Institute grant to study how transfer RNAs may fuel the spread of melanoma.

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  • Science, strength and survival: UMass Chan researcher, cancer patient inspires at 2025 UMass Cancer Walk

    Science, strength and survival: UMass Chan researcher, cancer patient inspires at 2025 UMass Cancer Walk

    The 27th annual UMass Cancer Walk at Polar Park raised more than $450,000 to support cancer research and clinical trials at UMass Chan.

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  • Chancellor Collins’ final Convocation address encourages optimism, determination

    Chancellor Collins’ final Convocation address encourages optimism, determination

    Four faculty members were honored with chancellor's medals at the annual Convocation and Investiture ceremony. 

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  • UMass Chan celebrates start of academic year with Convocation Week 2025

    UMass Chan celebrates start of academic year with Convocation Week 2025

    Festivities kick off on Friday, Sept. 5, with the T.H. Chan School of Medicine White Coat Ceremony.

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  • Richard Gregory named chair of molecular, cell & cancer biology

    Richard Gregory named chair of molecular, cell & cancer biology

    Richard I. Gregory, PhD, will join UMass Chan Medical School as the next chair of the Department of Molecular, Cell & Cancer Biology, beginning in December.

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