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Prabhani U. Atukorale, PhD

Research Focus - Engineering Immunomodulatory Nanomaterials Technologies for Reprogramming Tumor Microenvironment Immunity 

  • Design of nanomaterials that serve as drug carriers for multiple synergistic innate immune agonists
  • Development of novel cancer vaccination strategies
  • Reprogramming of immunity in difficult-to-treat cancers, including metastasis 
  • Improvement of efficacy of current clinical cancer immunotherapies, such as checkpoint inhibitors and CAR T cells, by combination with novel immunomodulatory nanoparticles 

Representative Publication

Atukorale PU, Raghunathan SP, Raguveer V, et al. Nanoparticle encapsulation of synergistic immune agonists enables systemic codelivery to tumor sites and IFNβ-driven antitumor immunity. Cancer Res. 2019;79(20):5394-5406.

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Getting Results…
  • UMass Cancer Center funds five UMass Chan research projects

    UMass Cancer Center funds five UMass Chan research projects

    The UMass Cancer Center Pilot Project Program has awarded seed grants to five UMass Chan Medical School research projects to enable investigators to gather pilot data for external cancer-focused funding.

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