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Michael Brehm, PhD

Research Focus - Regulation of Human T Cell Function and Homeostasis

  • Characterization of interactions between human T cells and tumors
  • Control of human T cell function within the tumor micro-environment by checkpoint blockade
  • Establishment of human avatar models to study immuno-oncology
  • Elucidation of cytokine control of human T cell responses

Representative Publication

Jangalwe S, Kapoor VN, Xu J, Girnius X, Kennedy NJ, Edwards YJK, Welsh RM, Davis RJ, Brehm MA(2019) Cutting Edge: Early attrition of memory T cells during inflammation and costimulation blockade is regulated concurrently by proapoptotic proteins Fas and Bim. J Immunol. 202(3):647-651.

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