Mary Munson, PhD

Research Focus - Elucidating the Molecular Mechanisms that Control Vesicle Membrane Trafficking

• Understanding the function of regulatory proteins and complexes that provide spatial and temporal control of membrane fusion in exocytosis and endocytosis
• Dissecting the function of exocytosis regulators in cell growth and division, and intercellular signaling 
• Uncovering critical insights into connections between regulators of the endocytic pathway with autophagy, apoptosis and neutrophil disorders 
• Exploring how upregulation or dysfunction of these regulatory factors contributes to cancer cell growth, metastasis and invasion

Representative Publication

Lepore DM, Martínez-Núñez L, Munson M. Exposing the elusive exocyst structure. Trends Biochem Sci. 2018;43(9):714-725.

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