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Joae Wu, PhD

Research Focus - Epigenetic Regulation of Tumor Metastasis, Cancer Metabolism, Drug Resistance and Cancer Stem Cells in Neuroblastoma

  • Protein arginine methyltransferase 5 (PRMT5) mediating tumor metastasis
  • SMARCA4/PRMT5 regulating the maintenance cancer stem cell population
  • SWI/SNF and co-factors rewiring cancer metabolism in tumor microenvironment
  • SMARCA4/PRMT5 modulating drug resistance

Representative Publication

Wu Q, Madany P, Dobson JR, et al. The BRG1 chromatic remodeling enzyme links cancer cell metabolism and proliferation. Oncotarget. 2016;7(25):38270-38281.

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  • Jason Shohet receives second Hyundai Hope on Wheels grant
    Research News

    Jason Shohet receives second Hyundai Hope on Wheels grant

    Hyundai Hope on Wheels has awarded Jason Shohet, MD, PhD, a second $300,000 Scholar Hope Grant to continue his research on neuroblastoma, a deadly cancer in children that affects the peripheral nervous system.

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