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Jennifer Benanti, PhD

Research Focus - Cell Cycle Regulation

  • Understanding the wiring of the cell cycle-regulatory network that controls the proliferation of normal cells and how this network is disrupted in cancer cells
  • Examining phosphoregulation of the transcription factor network that controls expression of cell cycle-regulated genes
  • Identifying ubiquitin ligases (E3s) and deubiquitinating enzymes (DUBs) that control degradation of cell cycle-regulatory proteins
  • Elucidating the ways in which the cell cycle-regulatory network is rewired when cells are exposed to environmental stress

Representative Publication

Landry BD, Mapa CE, Arsenault HE, Poti KE, Benanti JA. Regulation of a transcription factor network by Cdk1 coordinates late cell cycle gene expression. EMBO J. 2014;33(9):1044-1060.

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Getting Results…
  • Jennifer Benanti receives MIRA grant to advance understanding of how cells proliferate
    Research News

    Jennifer Benanti receives MIRA grant to advance understanding of how cells proliferate

    Jennifer A. Benanti, PhD, was recently awarded a federal Maximizing Investigators’ Research Award, or MIRA grant, to advance her lab’s study of molecular mechanisms of cell cycle control, a key factor in understanding cancer development. 

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