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Hong Zhang, PhD

Research Focus - Autophagy in Tumorigenesis

  • Maintenance of cellular homeostasis by autophagy
  • Role of phosphoinositides in autophagy regulation and tumorigenesis
  • Function of the p53-induced gene Ei24 in the basal autophagy pathway
  • Activation of systemic autophagy in the C. elegans germline tumor model system
  • Role of phase separation in tumorigenesis

Representative Publication

Tian Y, Li Z, Hu W, et al. C. elegans screen identifies autophagy genes specific to multicellular organisms. Cell. 2010;141(6):1042-1055.

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