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Craig Ceol, PhD

Research Focus - Melanoma Progression and Therapy

  • Identifying genes involved in melanoma progression
  • Determining the mechanistic basis of oncogenes and tumor suppressors in melanoma initiation
  • Defining the intersection of melanocyte stem cell biology and melanoma progression
  • Developing novel therapies to complement existing targeted immunotherapies

Representative Publication

Venkatesan AM, Vyas R, Gramann AK, et al. Ligand-activated BMP signaling inhibits cell differentiation and death to promote melanoma. J Clin Invest. 2018;128(1):294-308.

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More Publications

Inventions

Targeting GDF6 and BMP Signaling for Anti-cancer Therapy. UMMS15-21; Patent Pending.

A method of treating a melanoma in a subject, comprising administering to a subject an effective amount of an inhibitor of GDF6/BMP13 activity.

  • Technology: Small Molecules
  • Applications: Cancer, Myeloma

In the News

Getting Results…
  • U.S. Army grant advances UMMS studies targeting key melanoma protein
    Research News

    U.S. Army grant advances UMMS studies targeting key melanoma protein

    The U.S. Department of Defense awarded a team of researchers led by Craig J. Ceol, PhD, a $963,903 three-year grant to test potential approaches to killing metastatic melanoma tumors.

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