Athma Pai, PhD
Research Focus - The Efficiency of mRNA Splicing Regulation in Cancer
- Exploring the kinetics of mRNA splicing regulation.
- Investigating the tradeoff between temporal specificity and splice site fidelity in mis-regulated gene expression programs.
- Understanding the functional consequences of recurrent cancer-associated mutations in core splicing regulatory factors.
- Developing novel genomic approaches for measuring the temporal coordination between disparate steps of mRNA processing.
Representative Publication
Pai AA, Luca F. Environmental influences on RNA processing: Biochemical, molecular and genetic regulators of cellular response. Wiley Interdiscip Rev RNA. 2019 Jan;10(1):e1503.