Read up on the Center's latest developments in cancer research, screening and prevention, as well as innovations in cancer detection and treatment.
Apr 19, 2021
Advancing Lung Cancer Therapy Using Genetic Tools
Our studies have discovered that the genome (DNA) editing tool known as CRISPR-Cas9 can efficiently induce somatic genome editing in the lungs of adult animals. We designed various delivery vectors that could effectively deliver CRISPR editing components.
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Cancer Genetics,Lung Cancer,Researcher Spotlight, UMass Cancer Center
Apr 12, 2021
Paving the way for targeted cancer therapeutics
We hope to understand how to develop targeted therapies that are effective at suppressing tumor formation in neurofibromatosis type 1, through work in various model systems.
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Researcher Spotlight,Translational Oncology, UMass Cancer Center
Apr 5, 2021
Chromosome Biology and its Role in Genome Stability and Carcinogenesis
In earlier studies, we discovered that a human protein important for duplicating chromosomes also governs the three-dimensional localization of multiple proteins.
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Researcher Spotlight, UMass Cancer Center
Mar 29, 2021
Promoting Patient–Provider Conversations About Lung Cancer Screening, During the Surge of Covid
We have been working on a pilot research study that uses technology to facilitate effective communication between patients and healthcare providers about lung cancer screening.
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Lung Cancer,Researcher Spotlight, UMass Cancer Center
Mar 22, 2021
Mobilizing the Immune System to Fight Lung, Pancreatic, and Prostate Cancers
How to mobilize the immune system to target cancer? Our approach is to reactivate tumor suppressor pathways that are lost during tumor development, as a way to make tumors more visible and easier to target
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Researcher Spotlight, UMass Cancer Center
Dec 16, 2020
Exploring the Molecular Cell Biology of Aggressive Carcinomas
We are identifying mechanisms that account for the loss of differentiation and the highly aggressive behavior of these tumors
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Researcher Spotlight, UMass Cancer Center
Oct 12, 2020
Advancing a New Understanding of Hereditary Breast Cancer Genes
Our data indicate that chemotherapy works because it generates holes or gaps in DNA that are already present in cells lacking the hereditary breast and ovarian cancer genes.
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Breast Cancer,Researcher Spotlight, UMass Cancer Center