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Cancer Nexus Blog

Read up on the Center's latest developments in cancer research, screening and prevention, as well as innovations in cancer detection and treatment.

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    Developing a Targeted Therapy for Acute Myeloid Leukemia

    With support from the UMass Cancer Pilot Grant Program, Lucio Castilla, PhD, is working on a way to deliver a targeted therapy for inversion(16) acute myeloid leukemia. he is collaborating with S. Thai Thuyamanavan, PhD, an expert in drug delivery, to develop an antibody-nanogel conjugate capable of delivering a small molecule to AML cells and kill them.

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    The Darkest Side of Acute Myeloid Leukemia: The TP53 Mutation

    Learn why the TP53 mutation in acute myeloid leukemia is particularly worrisome and what Shyam Patel, MD, PhD is doing about it.

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    New Research Sheds Light on Treatment for TP53-Mutant Blood Cancers

    Dr. Patel discusses his new research defining the clinico-genomic landscape of TP53 mutations in patients with AML

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