2018 RESEARCH

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UMass Medical School researchers explain why cannabis may relieve intestinal inflammation

UMass Medical School researchers explain why cannabis may relieve intestinal inflammation

Beth McCormick, PhD, led a study that has for the first time identified a biological mechanism to explain why some marijuana users have reported beneficial effects from cannabis on intestine inflammation conditions such as ulcerative colitis and Crohn’s disease. 

Newsmaker: New RNAi therapeutic based on discoveries made at UMMS is approved by the FDA

Newsmaker: New RNAi therapeutic based on discoveries made at UMMS is approved by the FDA

On Aug. 10, 20 years after the initial discoveries related to RNA interference were made at UMass Medical School, the U.S. Food and Drug Administration has approved the first RNAi therapeutic for patients. Wide-spread media coverage of the breakthrough heralds a new era for disease treatment.

New genome-editing strategy developed at UMMS may lead to therapeutics

New genome-editing strategy developed at UMMS may lead to therapeutics

Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases. Dan Wang, PhD, is first author and Guangping Gao, PhD, is a co-corresponding author on the paper published in the Aug. 18 edition of Nature Biotechnology.

FDA approves first drug to use RNA interference, based on discoveries made at UMass Medical School

FDA approves first drug to use RNA interference, based on discoveries made at UMass Medical School

The new drug, patisiran, approved Aug. 10 by the FDA, is based on the discovery of RNAi made by Craig Mello, PhD, and Andrew Fire, PhD. It was developed by Alnylam, an RNAi-based drug development company co-founded by Phillip Zamore, PhD.

Summer undergraduate research ‘life changing’ for aspiring physician-scientists

Summer undergraduate research ‘life changing’ for aspiring physician-scientists

The Combined Summer Undergraduate Research Opportunity Class of 2018 wrapped up ten weeks of biomedical laboratory research in an immersive and challenging hands-on experience that will help inform their career decisions as physicians and biomedical scientists.

First-year medical student gaining research experience in organ preservation

First-year medical student gaining research experience in organ preservation

Medical student Jessica Perry is working in the lab of Paulo Martins, MD, PhD, this summer, with the support of a Carolyn L. Kuckein Student Research Fellowship from the Alpha Omega Alpha Honor Medical Society.

UMass Medical School, Brown University collaborate to improve health literacy among Deaf community

UMass Medical School, Brown University collaborate to improve health literacy among Deaf community

Melissa Anderson, PhD, of UMass Medical School, Tim Riker of Brown University’s Center for Language Studies and colleagues have been working to address low levels of health literacy within the Deaf community, due in part to the disconnect between biomedical researchers and the Deaf population.

Michael Francis lab identifies new model to study connectivity in the developing brain

Michael Francis lab identifies new model to study connectivity in the developing brain

In a paper published in the journal eLife, Michael Francis, PhD, and colleagues highlight a new role for the protein NRX-1, a synaptic organizer in the nervous system of the nematode C. elegans.

Changes to small RNA in sperm may help fertilization

Changes to small RNA in sperm may help fertilization

New research by Oliver J. Rando, MD, PhD, investigates how inheritable traits that are carried outside the genome are passed on from father to offspring. The studies appear in the journal Developmental Cell and provide new information about the epigenetic contribution of males to their offspring.

Paulo Martins recognized as Rising Star by International Liver Transplant Society

Paulo Martins recognized as Rising Star by International Liver Transplant Society

Paulo Martins, MD, PhD, assistant professor of surgery, has been recognized for his pioneering work in the area of liver transplantation by the International Liver Transplant Society.

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