Beth McCormick, PhD, led a study that has for the first time identified a biological mechanism to explain why some marijuana users have reported beneficial effects from cannabis on intestine inflammation conditions such as ulcerative colitis and Crohn’s disease.
On Aug. 10, 20 years after the initial discoveries related to RNA interference were made at UMass Medical School, the U.S. Food and Drug Administration has approved the first RNAi therapeutic for patients. Wide-spread media coverage of the breakthrough heralds a new era for disease treatment.
Researchers at UMass Medical School have developed a genome-editing strategy to correct disease-causing DNA mutations in mouse models of human genetic diseases. Dan Wang, PhD, is first author and Guangping Gao, PhD, is a co-corresponding author on the paper published in the Aug. 18 edition of Nature Biotechnology.
The new drug, patisiran, approved Aug. 10 by the FDA, is based on the discovery of RNAi made by Craig Mello, PhD, and Andrew Fire, PhD. It was developed by Alnylam, an RNAi-based drug development company co-founded by Phillip Zamore, PhD.
The Combined Summer Undergraduate Research Opportunity Class of 2018 wrapped up ten weeks of biomedical laboratory research in an immersive and challenging hands-on experience that will help inform their career decisions as physicians and biomedical scientists.
Medical student Jessica Perry is working in the lab of Paulo Martins, MD, PhD, this summer, with the support of a Carolyn L. Kuckein Student Research Fellowship from the Alpha Omega Alpha Honor Medical Society.
Melissa Anderson, PhD, of UMass Medical School, Tim Riker of Brown University’s Center for Language Studies and colleagues have been working to address low levels of health literacy within the Deaf community, due in part to the disconnect between biomedical researchers and the Deaf population.
In a paper published in the journal eLife, Michael Francis, PhD, and colleagues highlight a new role for the protein NRX-1, a synaptic organizer in the nervous system of the nematode C. elegans.
New research by Oliver J. Rando, MD, PhD, investigates how inheritable traits that are carried outside the genome are passed on from father to offspring. The studies appear in the journal Developmental Cell and provide new information about the epigenetic contribution of males to their offspring.
Paulo Martins, MD, PhD, assistant professor of surgery, has been recognized for his pioneering work in the area of liver transplantation by the International Liver Transplant Society.