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2020 RESEARCH

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UMMS scientists to expand 4D nucleome research with $13 million NIH grants

UMMS scientists to expand 4D nucleome research with $13 million NIH grants

Investigators at UMass Medical School have received two, five-year grants totaling $13 million to explore how the 4D genome structure influences gene expression, cellular function, development and disease as it reshapes itself. Job Dekker, PhD, and Paul Kaufman, PhD, to investigate architecture of genome as it changes over time.

PhD candidate receives predoctoral grant for study of eating disorders and social groups

PhD candidate receives predoctoral grant for study of eating disorders and social groups

Ariel Beccia, a PhD candidate in the Clinical & Population Health Research program, recently received a $98,000, three-year Predoctoral Individual National Research Service Award from the National Institutes of Health to study the social epidemiology of eating disorders by gender, sexual orientation and weight status.

H-ABC Foundation partners with UMass Medical School and Yale to study gene therapy for H-ABC

H-ABC Foundation partners with UMass Medical School and Yale to study gene therapy for H-ABC

The Foundation to Fight H-ABC has announced sponsored research agreements with UMass Medical School and Yale University to advance a targeted gene therapy for this rare degenerative children's disease. Guangping Gao, PhD, is leading the work at UMMS.

Sarah Nicole Forrester, Ann Moormann awarded $2 million NCI SeroNet grant

Sarah Nicole Forrester, Ann Moormann awarded $2 million NCI SeroNet grant

Sarah Nicole Forrester, PhD, and Ann Moormann, PhD, MPH, are co-principal investigators on a new grant aimed at enhancing representation of Black and Hispanic people in SARS-CoV-2 immunology research through the use of storytelling.

Axovant Gene Therapies receives rare pediatric disease designation for AXO-AAV-GM1 for GM1 gangliosidosis

Axovant Gene Therapies receives rare pediatric disease designation for AXO-AAV-GM1 for GM1 gangliosidosis

Axovant Gene Therapies Ltd. has announced it received rare pediatric disease designation from the FDA for AXO-AAV-GM1, an adeno-associated virus-based gene therapy that is in Phase I/II development for GM1 gangliosidosis. Miguel Sena-Esteves, PhD, is a principal scientist of the research programs.

Heidi Tissenbaum receives NIA grant to study how aging increases susceptibility to Alzheimer’s disease

Heidi Tissenbaum receives NIA grant to study how aging increases susceptibility to Alzheimer’s disease

Heidi Tissenbaum, PhD, was recently awarded a $460,000, two-year grant from the National Institute on Aging to explore at the molecular level the connections between aging, health, and the onset and severity of Alzheimer’s disease.

UMMS study to examine how different body fat plays a role in type 2 diabetes

UMMS study to examine how different body fat plays a role in type 2 diabetes

A new four-year, $2 million grant will allow Silvia Corvera, MD, to learn more about whether the development and function of two types of fat cells differ in people with type 2 diabetes, and may help explain what causes diabetes and obesity.

Kevin Gao receives Kirschstein Award for research into role of B cells in pulmonary fibrosis caused by SAVI

Kevin Gao receives Kirschstein Award for research into role of B cells in pulmonary fibrosis caused by SAVI

MD/PhD candidate Kevin Gao has received a Ruth L. Kirschstein National Research Service Award Individual Predoctoral Fellowship to study a rare autoinflammatory disease in infants called STING-associated vasculopathy with onset in infancy.

Shao-Hsien Liu studies racial disparities in total joint arthroplasty recovery

Shao-Hsien Liu studies racial disparities in total joint arthroplasty recovery

Racial disparities in utilization and outcomes of total joint arthroplasty, one of the most common surgical procedures performed in the United States, have persisted for 30 years, according to Shao-Hsien Liu, PhD.

From gut to brain: UMMS probes link between microbiome and cognitive functioning in Alzheimer’s patients

From gut to brain: UMMS probes link between microbiome and cognitive functioning in Alzheimer’s patients

UMass Medical School researchers have been awarded a $3.3 million, four-year National Institute on Aging grant to explore new understanding of how the gut microbiome influences cognitive functioning among elders living with Alzheimer’s disease.

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