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Neuroimmune interactions laboratory neuron images relative to study

Welcome to the Neuroimmune Interactions Laboratory Website

The NEUROIMMUNE INTRACTIONS LABORATORY is committed to the comprehensive investigation of various aspects of the IMMUNE RESPONSE, with a primary focus on the fields of NEUROIMMUNOLOGY, NEUROPATHOLOGY AND NEUROIMMUNOREGULATION.

Our primary research areas encompass:

  1. Investigating Neuropathogenesis in ZIKV Congenital Syndrome: We delve into the underlying CELLULAR and MOLECULAR mechanisms responsible for the neurological impact observed in Zika Virus (ZIKV) Congenital Syndrome. 
  2. Unraveling the miRNA Network in Regulating Neurodevelopment Genes during ZIKV Neuropathogenesis: Our goal is to discuss the intricate (miRNA) NETWORK that governs the expression of genes associated with neurodevelopment during the progression of ZIKV neuropathology.
  3. Exploring the innate Immune Response and its Role in Arbovirus Infections which are transmitted by arthopods like mosquitoes and ticks: Our research delves into the INNATE IMMUNE RESPONSE in controlling infections caused by arboviruses such as Zika Virus (ZIKV), Oropouche orthobunyavirus (OROV), Dengue virus (DENV), and West Nile Virus (WNV). 
  4. Examining the Function of Ionotropic Glutamate Receptor NMDAR on Immune Cells: We investigate the role of the N-Methyl-D-Aspartate (NMDAR) receptor found in neurons, which responds to glutamate, in immune cells. This research particularly focuses on how NMDAR modulates immune cells function and its relevance in the context of Experimental Autoimmune Encephalomyelitis (EAS), a murine model used in the study of Multiple Sclerosis.
  5. Exploring immune cells and the Interface of the Gut-Brain Axis: We assess potential correlations between the NMDAR expressed by immune cells and the immune system within the lamina propria, particularly in the context of colitis.
  6. Investigating Mesenchymal Stem Cells (MSCs) as Cellular Therapy for Neuroinflammation: Our research centers on evaluating the therapeutic potential of MESENCHYMAL STEM CELLS (MSCs) in mitigating neuroinflammatory conditions. We believe that MSCs derived from UTERINE TISSUE, given its immunosuppressive environment, may serve as a valuable THERAPEUTIC TOOL for neuroinflammatory diseases.
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