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Dietary intervention alters the microbiota and its byproducts improving patient’s outcomes

Inflammatory bowel diseases (IBD) are chronic disorders of the gastrointestinal tract that may be caused by inappropriate inflammatory responses to normal intestinal microbes, collectively called microbiome- in a genetically susceptible host. Several genes involved in the body’s immune response seem to predispose for IBD but genes alone can't explain the sharp rise in IBD incidence. Now we are looking at environmental conditions that can promote the development of the disease. Increasing evidence support that IBD patients exhibit an altered microbiome (harmful bacteria outnumbering the beneficial ones), which can be the lost piece of the puzzle. Given the increasing evidence of the role of diet in shaping the microbiome we aim to understand how diet could restore the microbiome in such a way as to reduce disease activity and improve outcomes for patients suffering with IBD.


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