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DSB Spotlight

A new paper published in Science from the Brewster lab finds a universal relationship between the fold-change enacted by a TF and the constitutive strenth of a regulated promoter across a diverse set of TFs, allowing gene expression buffering against perturbations to maintain cellular homeostasis. Learn more about this work, highlights from the experimiental journey and the first author Vinu Parisutham in this Q&A.

DSB Seminar Series

All seminars will take place at 11am in AS6-2072 (unless otherwise noted)

Cammie Lesser, MD,PhD
Professor, Tufts University School of Medicine
Title: “Bacterial delivery systems: from pathogenesis to therapeutics”
October 9, 2025
Host - Rob Brewster
 
Galit Lahav, PhD
Professor, Harvard Medical School
Friday, October 17, 2025 
Host - Amir Mitchell
 
Jen Oyler-Yaniv, PhD
Assistant Professor, Harvard Medical School
October 23, 2025
Host - Mike Lee
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DSB Spotlight

A new paper published in Science from the Brewster lab finds a universal relationship between the fold-change enacted by a TF and the constitutive strenth of a regulated promoter across a diverse set of TFs, allowing gene expression buffering against perturbations to maintain cellular homeostasis. Learn more about this work, highlights from the experimiental journey and the first author Vinu Parisutham in this Q&A.

DSB Seminar Series

All seminars will take place at 11am in AS6-2072 (unless otherwise noted)

Cammie Lesser, MD,PhD
Professor, Tufts University School of Medicine
Title: “Bacterial delivery systems: from pathogenesis to therapeutics”
October 9, 2025
Host - Rob Brewster
 
Galit Lahav, PhD
Professor, Harvard Medical School
Friday, October 17, 2025 
Host - Amir Mitchell
 
Jen Oyler-Yaniv, PhD
Assistant Professor, Harvard Medical School
October 23, 2025
Host - Mike Lee

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