Publications

Related Articles Wheat germ agglutinin-conjugated fluorescent pH sensors for visualizing proton fluxes. J Gen Physiol. 2020 Jun 01;152(6): Authors: Zhang L, Zhang M, Bellve K, Fogarty KE, Castro MA, Brauchi S, Kobertz WR Abstract Small-molecule f...

Related Articles Oddballs in the Shaker family: Kv2-related regulatory subunits. J Gen Physiol. 2018 12 03;150(12):1599-1601 Authors: Kobertz WR PMID: 30446508 [PubMed - indexed for MEDLINE]

Related Articles The Proton-Coupled Monocarboxylate Transporter Hermes Is Necessary for Autophagy during Cell Death. Dev Cell. 2018 11 05;47(3):281-293.e4 Authors: Velentzas PD, Zhang L, Das G, Chang TK, Nelson C, Kobertz WR, Baehrecke EH Abstract ...

Related Articles Palladium-Mediated Synthesis of a Near-Infrared Fluorescent K+ Sensor. J Org Chem. 2017 08 04;82(15):8199-8205 Authors: Bandara HMD, Hua Z, Zhang M, Pauff SM, Miller SC, Davie EAC, Kobertz WR Abstract Potassium (K+) exits electr...

Related Articles Fluorescent Visualization of Cellular Proton Fluxes. Cell Chem Biol. 2016 Dec 22;23(12):1449-1457 Authors: Zhang L, Bellve K, Fogarty K, Kobertz WR Abstract Cells use plasma membrane proton fluxes to maintain cytoplasmic and ex...

Related Articles Erratum to: Mutant SOD1 protein increases Nav1.3 channel excitability. J Biol Phys. 2016 06;42(3):371 Authors: Kubat Öktem E, Mruk K, Chang J, Akin A, Kobertz WR, Brown RH PMID: 27270492 [PubMed]

Related Articles Mutant SOD1 protein increases Nav1.3 channel excitability. J Biol Phys. 2016 06;42(3):351-70 Authors: Kubat Öktem E, Mruk K, Chang J, Akin A, Kobertz WR, Brown RH Abstract Amyotrophic lateral sclerosis (ALS) is a lethal paralyti...

Related Articles Bioreactive Tethers. Adv Exp Med Biol. 2015;869:77-100 Authors: Mruk K, Kobertz WR Abstract Ion channel complexes are challenging to study by traditional biochemical methods due to their membranous lipid environment and large siz...

Related Articles LQT1 mutations in KCNQ1 C-terminus assembly domain suppress IKs using different mechanisms. Cardiovasc Res. 2014 Dec 01;104(3):501-11 Authors: Aromolaran AS, Subramanyam P, Chang DD, Kobertz WR, Colecraft HM Abstract AIMS: Long ...

Related Articles The middle X residue influences cotranslational N-glycosylation consensus site skipping. Biochemistry. 2014 Aug 05;53(30):4884-93 Authors: Malaby HL, Kobertz WR Abstract Asparagine (N)-linked glycosylation is essential for effic...

Related Articles Calmodulation meta-analysis: predicting calmodulin binding via canonical motif clustering. J Gen Physiol. 2014 Jul;144(1):105-14 Authors: Mruk K, Farley BM, Ritacco AW, Kobertz WR Abstract The calcium-binding protein calmodulin ...

Related Articles Stoichiometry of the cardiac IKs complex. Proc Natl Acad Sci U S A. 2014 Apr 08;111(14):5065-6 Authors: Kobertz WR PMID: 24706929 [PubMed - indexed for MEDLINE]

Related Articles Molecular determinants of co- and post-translational N-glycosylation of type I transmembrane peptides. Biochem J. 2013 Aug 01;453(3):427-34 Authors: Malaby HL, Kobertz WR Abstract Type I transmembrane peptides acquire N-linked g...

Related Articles Chemical derivatization and purification of peptide-toxins for probing ion channel complexes. Methods Mol Biol. 2013;995:19-30 Authors: Hua Z, Kobertz WR Abstract Ion channels function as multi-protein complexes made up of ion-c...

Related Articles Structural insights into neuronal K+ channel-calmodulin complexes. Proc Natl Acad Sci U S A. 2012 Aug 21;109(34):13579-83 Authors: Mruk K, Shandilya SM, Blaustein RO, Schiffer CA, Kobertz WR Abstract Calmodulin (CaM) is a ubiqui...

Related Articles The acid-sensitive, anesthetic-activated potassium leak channel, KCNK3, is regulated by 14-3-3β-dependent, protein kinase C (PKC)-mediated endocytic trafficking. J Biol Chem. 2012 Sep 21;287(39):32354-66 Authors: Gabriel L, Lvov A, Orthodoxou D...

Related Articles Xenopus laevis oocytes infected with multi-drug-resistant bacteria: implications for electrical recordings. J Gen Physiol. 2011 Aug;138(2):271-7 Authors: O'Connell D, Mruk K, Rocheleau JM, Kobertz WR Abstract The Xenopus laevis ...

Related Articles Post-translational N-glycosylation of type I transmembrane KCNE1 peptides: implications for membrane protein biogenesis and disease. J Biol Chem. 2011 Aug 12;286(32):28150-9 Authors: Bas T, Gao GY, Lvov A, Chandrasekhar KD, Gilmore R, Kobertz W...

Related Articles O-glycosylation of the cardiac I(Ks) complex. J Physiol. 2011 Aug 01;589(Pt 15):3721-30 Authors: Chandrasekhar KD, Lvov A, Terrenoire C, Gao GY, Kass RS, Kobertz WR Abstract Post-translational modifications of the KCNQ1–KCNE1 (...

Related Articles Chemical control of metabolically-engineered voltage-gated K+ channels. Bioorg Med Chem Lett. 2011 Sep 01;21(17):5021-4 Authors: Hua Z, Lvov A, Morin TJ, Kobertz WR Abstract Metabolic oligosaccharide engineering is a powerful ap...

Related Articles Identification of a protein-protein interaction between KCNE1 and the activation gate machinery of KCNQ1. J Gen Physiol. 2010 Jun;135(6):607-18 Authors: Lvov A, Gage SD, Berrios VM, Kobertz WR Abstract KCNQ1 channels assemble wi...

Related Articles Discovery of a novel activator of KCNQ1-KCNE1 K channel complexes. PLoS One. 2009;4(1):e4236 Authors: Mruk K, Kobertz WR Abstract KCNQ1 voltage-gated K(+) channels (Kv7.1) associate with the family of five KCNE peptides to form ...

Related Articles Tethering chemistry and K+ channels. J Biol Chem. 2008 Sep 12;283(37):25105-9 Authors: Morin TJ, Kobertz WR Abstract Voltage-gated K+ channels are dynamic macromolecular machines that open and close in response to changes in mem...

Related Articles Counting membrane-embedded KCNE beta-subunits in functioning K+ channel complexes. Proc Natl Acad Sci U S A. 2008 Feb 05;105(5):1478-82 Authors: Morin TJ, Kobertz WR Abstract Ion channels are multisubunit proteins responsible fo...

Related Articles Secondary structure of a KCNE cytoplasmic domain. J Gen Physiol. 2006 Dec;128(6):721-9 Authors: Rocheleau JM, Gage SD, Kobertz WR Abstract Type I transmembrane KCNE peptides contain a conserved C-terminal cytoplasmic domain that...

Related Articles KCNE1 subunits require co-assembly with K+ channels for efficient trafficking and cell surface expression. J Biol Chem. 2006 Dec 29;281(52):40015-23 Authors: Chandrasekhar KD, Bas T, Kobertz WR Abstract KCNE peptides are a class ...

Related Articles KCNE3 truncation mutants reveal a bipartite modulation of KCNQ1 K+ channels. J Gen Physiol. 2004 Dec;124(6):759-71 Authors: Gage SD, Kobertz WR Abstract The five KCNE genes encode a family of type I transmembrane peptides that a...