Structural and Mechanistic Studies of Macromolecular Machines
The Lab
Uncovering the Principles of Molecular Machinery at the Atomic Level
We use a combination of biochemistry, biophysics and structural methods to elucidate how these vitally important protein complexes are integrated into cellular pathways.
Meet the LabResearch Focus
Structure and Mechanism of Large Macromolecular Complexes
The Kelch lab is interested in determining how macromolecular machines work, with special emphasis on machines involved in DNA replication and repair. Understanding how these machines work will not only illuminate the underpinnings of these critically important cellular pathways, but can also lead to new targets for the development of novel cancer therapeutics and antibiotics.
Read MorePublications
Follow our research, stay in touch – join the lab!
Twitter Feed
Contact Us
Office:
Lazare Research Building 923
Campus Map (pdf)
Phone:
508-856-8322 (office)
508-856-6868 (Lab)
Email:
Brian.Kelch@umassmed.edu
Mailing Address:
UMass Chan Medical School
Attn: Dr. Brian Kelch/BMB Department
364 Plantation St LRB923
Worcester, MA 01605
Join Us
We are always interested in applications from qualified candidates at postdoctoral and research associate levels.
Read more here
Undergraduates interested in pursuing a PhD at UMass Chan Medical School should apply directly to the Graduate School of Biomedical Sciences Program.