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Our Studies

The list below represents the currently approved studies for the Division of Gastroenterology at UMass:


Induction Study #2 - A Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Induction Therapy for Moderately to Severely Active Crohn’s Disease
Principal Investigator: Abbas Rupawala  

Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study of Oral Ozanimod as Maintenance Therapy for Moderately to Severely Active Crohn’s Disease
Principal Investigator: Abbas Rupawala  

A Phase 3, Multicenter, Open-Label Extension Study of Oral Ozanimod for Moderately to Severely Active Crohn’s Disease
Principal Investigator: Abbas Rupawala 

A Phase 4, Prospective, Open-label Study of Ozanimod to Explore the Safety, Efficacy, Quality of Life, and Biomarker Response in Participants with Moderate to Severe Ulcerative Colitis in Clinical Practice
Principal Investigator:  Abbas Rupawala

A Phase 2, Dose finding, Randomized, Double-blind, Placebo controlled, Multicenter Study to Evaluate the Safety and Efficacy of Efavaleukin Alfa Induction Therapy in Subjects with Moderately to Severely Active Ulcerative Colitis
Principal Investigator: JeanMarie Houghton

ACX-362E for Oral Treatment of Clostridioides difficile Infection: A Phase 2A Open-Label Segment Followed by a Phase 2B Double-Blind Vancomycin-Controlled Segment
Principal Investigator: JeanMarie Houghton

Outcomes and Data Collection for Fecal Microbiota Transplantation for the Treatment of Recurrent Clostridium difficile
Principal Investigator: Krunal Patel

Analysis of biologic samples from infectious and inflammatory GI diseases
Principal Investigator: JeanMarie Houghton         

Real-Time Cholangioscopy Artificial Intelligence Evaluation of Biliary Strictures
Principal Investigator: Neil Marya           

Prospective Collection of PillCam SB3 videos and raw data files with abnormal findings for Future Developments
Principal Investigator: Abbas Rupawala 

Patient Preference for an Implantable Device to Treat Liver Ascites
Principal Investigator: Deepika Devuni    

Patient and Caregiver Reported Outcomes in Adult Liver Transplant Candidates
Principal Investigator: Deepika Devuni    

Exploring barriers within the liver transplant evaluation care pathway and evaluating downstream effects
Principal Investigator: Deepika Devuni

Evaluating the relationship between organ rejection and cutaneous malignancy in liver transplant recipients
Principal Investigator: Deepika Devuni

Improving utilization of appropriate consultation for inpatient management of acute alcohol-related hepatitis 
Principal Investigator: Deepika Devuni

Evaluating reproductive health and health care maintenance, family planning, and contraception counseling in liver transplant recipients
Principal Investigator: Lauren Feld

Workforce Retention, Belonging and Burnout for Faculty in the Department of Medicine
Principal Investigator: Lauren Feld

Improving collection of women’s health history in female patients undergoing liver transplant evaluation: A quality improvement initiative                                                                                          
Principal Investigator: Deepika Devuni