Investigators

 Job Dekker  

Job Dekker, PhD
Professor Biochemistry and Molecular Pharmacology
Co-Director Program in Systems Biology
Investigator Howard Hughes Medical Institute
University of Massachusetts Medical School


To study the spatial organization of genomes and the roles of the three-dimensional arrangement of chromosomes in processes such as transcription regulation, chromosome segregation and genome stability, both in normal development and homeostasis and in human diseases such as cancer.  

 
 Garber  

Manuel Garber, PhD 
Associate Professor Program in Bioinformatics and Integrative Biology and Program in Molecular Medicine
Director Bioinformatics Core
University of Massachusetts Medical School


To study the evolution of transcriptional control and non-coding RNAs in mammals through development and analysis of sequence-based molecular biology approaches.

     
 Dale Greiner  

Dale Greiner, PhD
Professor Program in Molecular Medicine

Co-Director, Diabetes Center of Excellence
Dr. Eileen L. Berman and Stanley I. Berman
Foundation Chair in Biomedical Research Professor 
University of Massachusetts Medical School


Developing novel approaches for identifying the cause of human disease, including diabetes and cancers, and to test approaches to prevent and cure these diseases using a unique model system termed “humanized” mice that permits the study of functional human cells and tissues without putting patients at risk.

     
 

Jeremy Luban, MD
Professor Program in Molecular Medicine and
Biochemistry and Molecular Pharmacology
David J. Freelander Professor in AIDS Research
University of Massachusetts Medical School


     
 Rene Maehr  

Rene Maehr, PhD
Assistant Professor Diabetes Center of Excellence and
Program in Molecular Medicine
University of Massachusetts Medical School


 

     
 

Oliver Rando, MD/PhD 
Professor Biochemistry and Molecular Pharmacology
University of Massachusetts Medical School


 

     
 Scot Wolfe  

Scot Wolfe, PhD 
Professor Molecular, Cell and Cancer Biology
University of Massachusetts Medical School


Pursuing the development of artificial gene regulation and gene editing tools to evaluate gene function and provide foundational technology for gene therapy applications.

 

 

Nir Yosef, PhD 
Assistant Professor Department of Electrical Engineering and Computer Science, Center for Computational Biology
University of California Berkeley


To utilize high-throughput genomic data sets, mostly based on DNA sequencing,  in order to build models that explain how gene expression is regulated.  I have special interest in immune cells, covering various aspects of their biology, such as their differentiation, stability/plasticity, and response to acute stimulation.

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