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Biochemistry and Molecular Biotechnology Department

Our mission is to illuminate the molecular mechanisms that govern basic biological processes, with an emphasis on integrative strategies to reveal fundamental mechanistic insights and develop new therapeutic paradigms empowered by a collaborative, diverse & inclusive community.

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two people looking at a transparent petri dish above the text mentors to the next generation of scientific changemakers

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BMB Blog Posts

Jul 31, 2024

Celebrating RNA Day with Dr. Thoru Pederson

Join us (the BMB) in celebrating RNA Day by learning more about the innovative bioengineering by the Pederson Lab.

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May 10, 2024

Dr. Brian Kelch Receives the Education Service Award, 2024

Dr. Brian Kelch received the Education Service Award in 2024! Learn more about his dedication to education in this blog post.

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Check out more of our blogs here!

Latest News

Latest BMB news as reported by the UMass Chan Communications Office

UMass Memorial Health gift, with matching funds from UMass Foundation, to fund five new endowed chairs at UMass Chan

September 19, 2024
Convocation 2024: UMass Chan racing toward ambitious future

September 13, 2024
Morningside Graduate School of Biomedical Sciences celebrates largest class at qualifying exam ceremony

September 12, 2024
UMass Chan kicks off 2024 academic year with weeklong Convocation celebration

August 30, 2024
UMass Chan neuroscientist receives $4.1 million Transformative Research Award to study Down syndrome

July 16, 2024
UMass Chan BRIDGE Fund commits $2M in six faculty projects

July 03, 2024
Morningside Graduate School of Biomedical Sciences celebrates milestones of IMSD, PREP students

June 18, 2024
Advancing gender equity, importance of mentoring highlighted at Women’s Faculty Awards

May 24, 2024
Twenty rising faculty members graduate from Junior Faculty Development Program

May 17, 2024
Celia A. Schiffer elected to National Academy of Sciences

May 03, 2024
Mary Munson, Craig Peterson named American Association for the Advancement of Science fellows

April 18, 2024
Zhiping Weng named inaugural chair of the Department of Genomics & Computational Biology

November 03, 2023
Celebrating collaboration, UMass Chan launches ‘Advancing Together’ brand

September 06, 2023
Kirschstein award to fund PhD candidate’s research on HTLV-1

August 16, 2023
Summer undergraduate research students highlight collaboration, diversity at UMass Chan

August 10, 2023
Munson lab receives NIH award for research on intracellular cargo transport

August 09, 2023

Check out more news here!

Recent Publications

Total: 15 results

Nuclear bodies: concentrating at an aqueous site, with momentum

Tuesday, September 17, 2024

Author(s): Ling-Ling Chen,Erica Larschan,A Gregory Matera,Amy Strom,Thoru Pederson

Source: Nucleus (Austin, Tex.)
Enhanced Sample Multiplexing-Based Targeted Proteomics with Intelligent Data Acquisition

Tuesday, September 10, 2024

Author(s): Ka Yang,Joao A Paulo,Steven P Gygi,Qing Yu

Source: Journal of the American Society for Mass Spectrometry
The asymmetric opening of HIV-1 Env by a potent CD4 mimetic enables anti-coreceptor binding site antibodies to mediate ADCC

Tuesday, September 10, 2024

Author(s): Jonathan Richard,Michael W Grunst,Ling Niu,Marco A Díaz-Salinas,William D Tolbert,Lorie Marchitto,Fei Zhou,Catherine Bourassa,Derek Yang,Ta Jung Chiu,Hung-Ching Chen,Mehdi Benlarbi,Guillaume-Beaudoin-...

Source: bioRxiv : the preprint server for biology
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity

Monday, September 09, 2024

Author(s): Lorie Marchitto,Jonathan Richard,Jérémie Prévost,Alexandra Tauzin,Derek Yang,Ta-Jung Chiu,Hung-Ching Chen,Marco A Díaz-Salinas,Manon Nayrac,Mehdi Benlarbi,Guillaume Beaudoin-Bussières,Sai Priya Anand,...

Source: Journal of virology
Conformational dynamics of the HIV-1 envelope glycoprotein from CRF01_AE is associated with susceptibility to antibody-dependent cellular cytotoxicity

Wednesday, September 04, 2024

Author(s): Marco A Díaz-Salinas,Debashree Chatterjee,Manon Nayrac,Halima Medjahed,Jérémie Prévost,Marzena Pazgier,Andrés Finzi,James B Munro

Source: bioRxiv : the preprint server for biology
Long wavelength near-infrared and red light-driven consecutive photo-induced electron transfer for highly effective photoredox catalysis

Friday, August 23, 2024

Author(s): Le Zeng,Ling Huang,Zhi Huang,Tomoyasu Mani,Kai Huang,Chunying Duan,Gang Han

Source: Nature communications
ASCB statement of commitment to diversity, equity, and inclusion

Monday, July 22, 2024

Author(s): Sandra A Murray,Erika L F Holzbaur,Mary Munson,Daniela Cimini,Timothy F Lane,Rebecca Alvania,Derek A Applewhite,Fred Chang,Elizabeth H Chen,William C Earnshaw,Chantell S Evans,Rong Li,Beata E Mierzwa,...

Source: Molecular biology of the cell
PRC1.6 localizes on chromatin with the human silencing hub (HUSH) complex for promoter-specific silencing

Friday, July 19, 2024

Author(s): Tomás C Rodríguez,Leonid Yurkovetskiy,Karthika Nagalekshmi,Chin Hung Oscar Lam,Eva Jazbec,Stacy A Maitland,Scot A Wolfe,Erik J Sontheimer,Jeremy Luban

Source: bioRxiv : the preprint server for biology
Single-molecule imaging reveals allosteric stimulation of SARS-CoV-2 spike receptor binding domain by host sialic acid

Wednesday, July 17, 2024

Author(s): Marco A Díaz-Salinas,Aastha Jain,Natasha D Durham,James B Munro

Source: Science advances
Polycomb function in early mouse development

Friday, July 12, 2024

Author(s): Livia Condemi,Ivano Mocavini,Sergi Aranda,Luciano Di Croce

Source: Cell death and differentiation
IFIH1 (MDA5) is required for innate immune detection of intron-containing RNA expressed from the HIV-1 provirus

Wednesday, July 10, 2024

Author(s): Mehmet Hakan Guney,Karthika Nagalekshmi,Sean Matthew McCauley,Claudia Carbone,Ozkan Aydemir,Jeremy Luban

Source: Proceedings of the National Academy of Sciences of the United States of America
Structures and Functions of the Human GATOR1 Complex

Thursday, July 04, 2024

Author(s): Ilina Ivanova,Kuang Shen

Source: Sub-cellular biochemistry
The HHV-6B U20 glycoprotein binds ULBP1, masking it from recognition by NKG2D and interfering with natural killer cell activation

Tuesday, July 02, 2024

Author(s): Grant C Weaver,Christine L Schneider,Aniuska Becerra-Artiles,Kiera L Clayton,Amy W Hudson,Lawrence J Stern

Source: Frontiers in immunology
The combination of three CD4-induced antibodies targeting highly conserved Env regions with a small CD4-mimetic achieves potent ADCC activity

Wednesday, June 19, 2024

Author(s): Lorie Marchitto,Jonathan Richard,Jérémie Prévost,Alexandra Tauzin,Derek Yang,TaJung Chiu,Hung-Ching Chen,Marco A Díaz-Salinas,Manon Nayrac,Mehdi Benlarbi,Guillaume Beaudoin-Bussières,Sai Priya Anand,K...

Source: bioRxiv : the preprint server for biology
Muscle-specific pyruvate kinase isoforms, PKM1 and PKM2, regulate mammalian SWI/SNF proteins and histone 3 phosphorylation during myoblast differentiation

Wednesday, June 05, 2024

Author(s): Monserrat Olea-Flores,Tapan Sharma,Odette Verdejo-Torres,Imaru DiBartolomeo,Paul R Thompson,Teresita Padilla-Benavides,Anthony N Imbalzano

Source: FASEB journal : official publication of the Federation of American Societies for Experimental Biology

A full list of department publications can be found here.

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