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Thoru Pederson, Ph.D.Academic Role: ProfessorFaculty Appointment(s) and Affiliations:
Graduate School of Biomedical SciencesBiochemistry & Molecular Pharmacology Graduate ProgramInterdisciplinary Graduate Program
Programs, Centers & Institutes
Program in Cell Dynamics Vitold Arnett Professor of Cell BiologyRNA traffic in eukaryotic cells, RNA processing, RNA-protein interactions, siRNA
We are investigating the functional significance of specific protein-RNA interactions in eukaryotic gene expression, with particular emphasis on RNA traffic and processing. We have also been combining in situ RNA detection methods with novel approaches we have developed for following fluorescent RNA molecules in living mammalian cells. One current focus is the assembly of the signal recognition particle. We are also studying the transport of various RNAs within the nucleus (see video link below). Another major project concerns novel functions of the nucleolus (beyond its role in ribosome production), with particular emphasis on cell cycle progression and checkpoints.
Office: B4-337
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364 Plantation Street Worcester, MA 01605