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Publications 2017

Yichao Fan, Jiao Yue, Mengtao Xiao, Han Han-Zhang, Yao Vickie Wang, Chun Ma, Zhilin Deng, Yingxiang Li, Yanyan Yu, Xinghao Wang, Shen Niu, Youjia Hua, Zhiping Weng, Peter Atadja, En Li, Bin Xiang.
FXR1 regulates transcription and is required for growth of human cancer cells with TP53/FXR2 homozygous deletion.
eLife. 6: e26129. 

NK Singh, TP Riley, SCB Baker, T Borrman, Z Weng, BM Baker.
Emerging Concepts in TCR Specificity: Rationalizing and (Maybe) Predicting Outcomes.
The Journal of Immunology 199 (7), 2203-2213 

Brian G Pierce, Elisabeth N Boucher, Kurt H Piepenbrink, Monir Ejemel, Chelsea A Rapp, William D Thomas, Eric J Sundberg, Zhiping Weng, Yang Wang.
Structure-Based Design of Hepatitis C Virus Vaccines That Elicit Neutralizing Antibody Responses to a Conserved Epitope.
Journal of Virology. 91: e01032-17. 

SS Parhad, S Tu, Z Weng+, WE Theurkauf+.
Adaptive Evolution Leads to Cross-Species Incompatibility in the piRNA Transposon Silencing Machinery.
Developmental Cell. 43 (1): 60-70. e5. 
+co-corresponding authors

Anton G Henssen, Richard Koche, Jiali Zhuang, Eileen Jiang, Casie Reed, Amy Eisenberg, Eric Still, Ian C MacArthur, Elias Rodríguez-Fos, Santiago Gonzalez, Montserrat Puiggròs, Andrew N Blackford, Christopher E Mason, Elisa de Stanchina, Mithat Gönen, Anne-Katrin Emde, Minita Shah, Kanika Arora, Catherine Reeves, Nicholas D Socci, Elizabeth Perlman, Cristina R Antonescu, Charles WM Roberts, Hanno Steen, Elizabeth Mullen, Stephen P Jackson, David Torrents, Zhiping Weng, Scott A Armstrong, Alex Kentsis.
PGBD5 promotes site-specific oncogenic mutations in human tumors.
Nature genetics 49 (7), 1005-1014 

Haiwei Mou, Jordan L Smith, Lingtao Peng, Hao Yin, Jill Moore, Xiao-Ou Zhang, Chun-Qing Song, Ankur Sheel, Qiongqiong Wu, Deniz M Ozata, Yingxiang Li, Daniel G Anderson, Charles P Emerson, Erik J Sontheimer, Melissa J Moore, Zhiping Weng, Wen Xue.
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion.
Genome Biology 18 (1), 108 

Tyler Borrman, Jennifer Cimons, Michael Cosiano, Michael Purcaro, Brian G Pierce, Brian M Baker, Zhiping Weng.
ATLAS: A database linking binding affinities with structures for wild‐type and mutant TCR‐pMHC complexes.
Proteins: Structure, Function, and Bioinformatics 85 (5), 908-916

Chun-Qing Song, Yingxiang Li, Haiwei Mou, Jill Moore, Angela Park, Yotsawat Pomyen, Soren Hough, Zachary Kennedy, Andrew Fischer, Hao Yin, Daniel G Anderson, Darryl Conte, Lars Zender, Xin Wei Wang, Snorri Thorgeirsson, Zhiping Weng, Wen Xue.
Genome-wide CRISPR screen identifies regulators of mitogen-activated protein kinase as suppressors of liver tumors in mice.
Gastroenterology 152 (5), 1161-1173. e1 

Haiwei Mou, Jill Moore, Sunil K Malonia, Yingxiang Li, Deniz M Ozata, Soren Hough, Chun-Qing Song, Jordan L Smith, Andrew Fischer, Zhiping Weng, Michael R Green, Wen Xue.
Genetic disruption of oncogenic Kras sensitizes lung cancer cells to Fas receptor-mediated apoptosis.
Proceedings of the National Academy of Sciences 114 (14), 3648-3653 

T Vreven, BG Pierce, TM Borrman, Z Weng.
Performance of ZDOCK and IRAD in CAPRI rounds 28–34.
Proteins: Structure, Function, and Bioinformatics 85 (3), 408-416 

Iain H Moal, Didier Barradas-Bautista, Brian Jiménez-García, Mieczyslaw Torchala, Arjan van der Velde, Thom Vreven, Zhiping Weng, Paul A Bates, Juan Fernández-Recio.
IRaPPA: information retrieval based integration of biophysical models for protein assembly selection.
Bioinformatics 33 (12), 1806-1813 

Tanggis Bohnuud, Lingqi Luo, Shoshana J Wodak, Alexandre MJJ Bonvin, Zhiping Weng, Sandor Vajda, Ora Schueler-Furman, Dima Kozakov.
A benchmark testing ground for integrating homology modeling and protein docking.
Proteins: Structure, Function, and Bioinformatics 2017 Jan; 85 (1), 10-16