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Clinical and Translational Research in Plastic Surgery

Lab Staff - Plastic Surgery Research LabActive areas of investigation include:

General Plastic Surgery
Applications of fat grafting, mitigation of surgical drain complications, pressure sore prevention 

Updated population based cephalic index norms, neonatal mandibular distraction  

Radiation and thermal injury effects on skin and their mitigation, external volume expansion devices, ventral hernia closure

Global Health
Quality and safety outcomes on international plastic surgery volunteer trips, best practices around global health education.

All faculty and residents are actively involved in plastic surgery research and frequently present at regional, national and international forums including New England Society of Plastic and Reconstructive Surgery, the annual meeting of the American Society of Plastic Surgery, the American Association of Plastic Surgeons, American Society of Reconstructive Microsurgery, the International Hernia Society and The International Society of Craniofacial Surgery.

Joyce McIntyre, MD – Joyce McIntyre, MD, is a board-certified plastic surgeon specializing in craniofacial and pediatric plastic surgery and is assistant professor of surgery, pediatrics and neurosurgery.  She is associate program director of the UMass Chan Plastic Surgery Residency Program and staff surgeon for both the UMass Memorial Health Craniofacial team and the cleft team at Shriners Hospital for Children in Springfield, Mass.

Areas of special interest to Dr. McIntyre include complex craniofacial and skull disorders, quality and outcome measures in international plastic surgery, cleft lip and palate, functional problems with the jaw and airway, neonatal mandibular distraction, orthognathic surgery, vascular malformations, and general pediatric plastic surgery.  She also staffs a regional plastic surgery clinic on Cape Cod where the Division of Plastic Surgery has been a leader in using telehealth technologies to increase patients’ access to reconstructive surgery. 

McIntyre graduated from Harvard College, UMass Chan Medical School, UMass Chan Integrated Plastic Surgery Residency Program and the Craniofacial Fellowship at Rady Children’s Hospital San Diego and the University of California San Diego.

Janice F. Lalikos, MD – Janice F. Lalikos, MD, graduated from Johns Hopkins University School of Medicine with an MD and a master’s in medical illustration. She did a full general surgery residency training at Vanderbilt University Hospital and was board certifiedy the American Board of Surgery and is a fellow of the American College of Surgeons. Her plastic surgery residency was completed at UMass Medical School, and her craniofacial fellowship at the University of Pittsburgh - Presbyterian Medical Center. She is by the American Board of Plastic Surgery and is an ABPS Board Examiner. Dr. Lalikos’ clinical interests include pediatric plastic surgery, wound care and tissue engineering. She has more than 50 peer reviewed publications, 12 grants and one patent. Lalikos is professor, residency program director and section chief, pediatric plastic surgery at the UMass Chan Medical School. 

The Office of Clinical Research

The Office of Clinical Research is the contracting entity for clinical research at UMass Chan Medical School. For further information, please visit the website at

The Clinical Trials Unit (CTU) is under the supervision of the Office of Research. The CTU is locatedin the Ambulatory Care Center. The specialized clinical trials unit is a comfortable and accessible area for study participants. The space includes a waiting area; a conference room for study initiation, monitor visits and education meetings; four staff offices; three workstations for visiting staff; four exam rooms; an infusion room with two recliners; and a private infusion room for those subjects requiring special services.

The OOR also provides services such as: 

  • Promoting clinical investigator interests through industry liaisons
  • Assistance with feasibility review of new studies
  • Careful review and assessment of clinical study budgets
  • Thorough and timely review of clinical trial agreements
  • Educational and training opportunities for clinical research staff
  • Investigational pharmacy support and consultation
  • Quality Improvement Initiative

For additional information about clinical study/trial agreements, please contact Danielle Howard, director, Clinical Research Operations at UMass Chan Medical School at 508-856-8981 or e-mail at

Investigational Pharmacy Services

The Investigational Pharmacy Service plays a key role in facilitating subject safety for clinical trials being conducted at UMass Chan and UMass Memorial Medical Center. Housed in the clinical system's ambulatory pharmacy, the service is staffed with two full-time investigational pharmacists and a pharmacy technician.

The investigational pharmacy has a critical role in safe clinical trial conduct as it directs receipt, dispensing and storage of investigational drugs. It also has a distinct role as investigator consultant, regulatory expert and compliance professional as it relates to study drugs and their use.

For additional information, please contact:

For additional information on wound research, please contact Raymond M. Dunn, MD, at

Most Recent Publications (2021-2022):

Wood JJ, Gu G, Guber RD, Rothkopf DM. Impending Backlog of Cleft Palate Patients Due to COVID-19. Ann Glob Health. 2022; 88(1):9. PMID: 35087709.

Akyurek M, Caragacianu D. Oncoplastic reconstruction of central lumpectomy defects using the medial pillar island flap. J Plast Reconstr Aesthet Surg. 2021 Nov; 74(11):2863-2869. PMID: 34011471.

Matsumine H, Giatsidis G, Fujimaki H, Yoshimoto N, Makino Y, Hosoi S, Takagi M, Shimizu M, Takeuchi M. NPWTi allows safe delayed free flap repair of Gustilo IIIb injuries: A prospective case series. Regen Ther. 2021 Dec; 18:82-87. PMID: 33997186.

Asaad M, Drolet BC, Janis JE, Giatsidis G. Applicant Familiarity Becomes Most Important Evaluation Factor in USMLE Step I Conversion to Pass/Fail: A Survey of Plastic Surgery Program Directors. J Surg Educ. 2021 Sep-Oct; 78(5):1406-1412. PMID: 33487585

McCarthy M, Prete VI, Oh S, Gu G, Lujan-Hernandez J, Stamer D, Lalikos J. The Use of Visible-Light Hyperspectral Imaging in Evaluating Burn Wounds: A Case Report. J Burn Care Res. 2021 08 04; 42(4):825-828. PMID: 33914874.

Phelan AL, Gu G, McCarthy M, Barton BA, McIntyre JK, Lalikos JF. Rethinking Farkas: Updating Cephalic Index Norms in a Large, Diverse Population. Plast Reconstr Surg. 2021 Jun 01; 147(6):1369-1376. PMID: 33973960.

Lujan-Hernandez J, Chin MS, Lancerotto L, Lalikos JF. Reply: Increasing Fat Graft Retention in Irradiated Tissue after Preconditioning with External Volume Expansion. Plast Reconstr Surg. 2021 01 01; 147(1):159e-160e. PMID: 33027200.