Research Focus: Understanding host-pathogen interactions – intersection of inflammation and cell death pathways

• Mechanisms for pathogen activation and inhibition of Innate Immunity – inflammasomes, TLRs, regulated cell death.
• Manipulation of signaling by bacterial secretion system effectors from Yersinia and Salmonella, and subsequent host backup responses
• Non-infectious innate immune signaling, induced by vaccines, metabolism and neuroinflammatory diseases

Learn more about the Lien lab's work.