Rhind Lab Publications | UMass Chan Medical School, Worcester, MA

In through the out door: A loop-binding-first model for topological cohesin loading

lunes, agosto 19, 2024

Author(s): Nicholas Rhind

Source: BioEssays : news and reviews in molecular, cellular and developmental biology

pomBseen: An automated pipeline for analysis of fission yeast images

martes, septiembre 12, 2023

Author(s): Makoto Ohira,Nicholas Rhind

Source: PloS one

Short-term molecular consequences of chromosome mis-segregation for genome stability

sábado, marzo 11, 2023

Author(s): Lorenza Garribba,Giuseppina De Feudis,Valentino Martis,Martina Galli,Marie Dumont,Yonatan Eliezer,René Wardenaar,Marica Rosaria Ippolito,Divya Ramalingam Iyer,Andréa E Tijhuis,Diana C J Spierings,Mich...

Source: Nature communications

A high-quality reference genome for the fission yeast Schizosaccharomyces osmophilus

martes, febrero 07, 2023

Author(s): Guo-Song Jia,Wen-Cai Zhang,Yue Liang,Xi-Han Liu,Nicholas Rhind,Alison Pidoux,Michael Brysch-Herzberg,Li-Lin Du

Source: G3 (Bethesda, Md.)

Exploring the experiences and perceptions of participating in a peer-support intervention for adults with chronic non-cancer pain: a qualitative systematic review

viernes, febrero 03, 2023

Author(s): Rachel Arnott,Victoria Park,Nicola Rhind,Kay Cooper

Source: JBI evidence synthesis

DNA replication timing: Biochemical mechanisms and biological significance

martes, septiembre 20, 2022

Author(s): Nicholas Rhind

Source: BioEssays : news and reviews in molecular, cellular and developmental biology

Mapping replication forks, one replicon at a time

viernes, abril 08, 2022

Author(s): Nicholas Rhind

Source: Molecular cell

f = m*a: A Framework for Investigating the Regulation of Replication Timing

viernes, febrero 25, 2022

Author(s): Nicholas Rhind

Source: Genes

Cell-size control

martes, noviembre 09, 2021

Author(s): Nicholas Rhind

Source: Current biology : CB

Genome-wide mapping of human DNA replication by optical replication mapping supports a stochastic model of eukaryotic replication

martes, junio 22, 2021

Author(s): Weitao Wang,Kyle N Klein,Karel Proesmans,Hongbo Yang,Claire Marchal,Xiaopeng Zhu,Tyler Borrman,Alex Hastie,Zhiping Weng,John Bechhoefer,Chun-Long Chen,David M Gilbert,Nicholas Rhind

Source: Molecular cell

The capacity of origins to load MCM establishes replication timing patterns

jueves, marzo 25, 2021

Author(s): Livio Dukaj,Nicholas Rhind

Source: PLoS genetics

The fission yeast S-phase cyclin Cig2 can drive mitosis

lunes, marzo 08, 2021

Author(s): Mary Pickering,Mira Magner,Dan Keifenheim,Nicholas Rhind

Source: Genetics

Fission yeast cells grow approximately exponentially

martes, abril 09, 2019

Author(s): Mary Pickering,Lauren Nicole Hollis,Edridge D'Souza,Nicholas Rhind

Source: Cell cycle (Georgetown, Tex.)

Transcriptome-wide Interrogation of the Functional Intronome by Spliceosome Profiling

sábado, mayo 05, 2018

Author(s): Weijun Chen,Jill Moore,Hakan Ozadam,Hennady P Shulha,Nicholas Rhind,Zhiping Weng,Melissa J Moore

Source: Cell

Cell Size Control via an Unstable Accumulating Activator and the Phenomenon of Excess Mitotic Delay

viernes, diciembre 29, 2017

Author(s): Nicholas Rhind

Source: BioEssays : news and reviews in molecular, cellular and developmental biology

Replication fork slowing and stalling are distinct, checkpoint-independent consequences of replicating damaged DNA

martes, agosto 15, 2017

Author(s): Divya Ramalingam Iyer,Nicholas Rhind

Source: PLoS genetics

Analysis of DNA Replication in Fission Yeast by Combing

domingo, julio 23, 2017

Author(s): Divya R Iyer,Shankar Das,Nick Rhind

Source: Cold Spring Harbor protocols

Chromosome Mis-segregation Generates Cell-Cycle-Arrested Cells with Complex Karyotypes that Are Eliminated by the Immune System

miércoles, junio 21, 2017

Author(s): Stefano Santaguida,Amelia Richardson,Divya Ramalingam Iyer,Ons M'Saad,Lauren Zasadil,Kristin A Knouse,Yao Liang Wong,Nicholas Rhind,Arshad Desai,Angelika Amon

Source: Developmental cell

Global increase in replication fork speed during a p57KIP2-regulated erythroid cell fate switch

jueves, junio 01, 2017

Author(s): Yung Hwang,Melinda Futran,Daniel Hidalgo,Ramona Pop,Divya Ramalingam Iyer,Ralph Scully,Nicholas Rhind,Merav Socolovsky

Source: Science advances

Size-Dependent Expression of the Mitotic Activator Cdc25 Suggests a Mechanism of Size Control in Fission Yeast

martes, mayo 09, 2017

Author(s): Daniel Keifenheim,Xi-Ming Sun,Edridge D'Souza,Makoto J Ohira,Mira Magner,Michael B Mayhew,Samuel Marguerat,Nicholas Rhind

Source: Current biology : CB

An estradiol-inducible promoter enables fast, graduated control of gene expression in fission yeast

jueves, abril 20, 2017

Author(s): Makoto J Ohira,David G Hendrickson,R Scott McIsaac,Nicholas Rhind

Source: Yeast (Chichester, England)

The Intra-S Checkpoint Responses to DNA Damage

martes, febrero 21, 2017

Author(s): Divya Ramalingam Iyer,Nicholas Rhind

Source: Genes

Corrigendum: Replication timing is regulated by the number of MCMs loaded at origins

sábado, diciembre 10, 2016

Author(s): Shankar P Das,Tyler Borrman,Victor W T Liu,Scott C-H Yang,John Bechhoefer,Nicholas Rhind

Source: Genome research

Identification of S-phase DNA damage-response targets in fission yeast reveals conservation of damage-response networks

miércoles, junio 15, 2016

Author(s): Nicholas A Willis,Chunshui Zhou,Andrew E H Elia,Johanne M Murray,Antony M Carr,Stephen J Elledge,Nicholas Rhind

Source: Proceedings of the National Academy of Sciences of the United States of America

How and why multiple MCMs are loaded at origins of DNA replication

sábado, mayo 14, 2016

Author(s): Shankar P Das,Nicholas Rhind

Source: BioEssays : news and reviews in molecular, cellular and developmental biology

Discovery of genes involved in mitosis, cell division, cell wall integrity and chromosome segregation through construction of Schizosaccharomyces pombe deletion strains

jueves, mayo 12, 2016

Author(s): Jun-Song Chen,Janel R Beckley,Liping Ren,Anna Feoktistova,Michael A Jensen,Nicholas Rhind,Kathleen L Gould

Source: Yeast (Chichester, England)

Replication timing is regulated by the number of MCMs loaded at origins

sábado, septiembre 12, 2015

Author(s): Shankar P Das,Tyler Borrman,Victor W T Liu,Scott C-H Yang,John Bechhoefer,Nicholas Rhind

Source: Genome research

Incorporation of thymidine analogs for studying replication kinetics in fission yeast

miércoles, abril 29, 2015

Author(s): Nicholas Rhind

Source: Methods in molecular biology (Clifton, N.J.)

Identification of new players in cell division, DNA damage response, and morphogenesis through construction of Schizosaccharomyces pombe deletion strains

viernes, enero 02, 2015

Author(s): Jun-Song Chen,Janel R Beckley,Nathan A McDonald,Liping Ren,MariaSanta Mangione,Sylvia J Jang,Zachary C Elmore,Nicole Rachfall,Anna Feoktistova,Christine M Jones,Alaina H Willet,Rodrigo Guillen,Danny A...

Source: G3 (Bethesda, Md.)

The three most important things about origins: location, location, location

martes, abril 08, 2014

Author(s): Nicholas Rhind

Source: Molecular systems biology

Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes

martes, enero 21, 2014

Author(s): Weijun Chen,Hennady P Shulha,Ami Ashar-Patel,Jing Yan,Karin M Green,Charles C Query,Nick Rhind,Zhiping Weng,Melissa J Moore

Source: RNA (New York, N.Y.)

Checkpoint regulation of replication forks: global or local?

viernes, noviembre 22, 2013

Author(s): Divya Ramalingam Iyer,Nicholas Rhind

Source: Biochemical Society transactions

The DNA damage and the DNA replication checkpoints converge at the MBF transcription factor

viernes, septiembre 06, 2013

Author(s): Tsvetomira Ivanova,Isabel Alves-Rodrigues,Blanca Gómez-Escoda,Chaitali Dutta,James A DeCaprio,Nick Rhind,Elena Hidalgo,José Ayté

Source: Molecular biology of the cell

Fission yeast nucleolar protein Dnt1 regulates G2/M transition and cytokinesis by downregulating Wee1 kinase

viernes, septiembre 06, 2013

Author(s): Zhi-Yong Yu,Meng-Ting Zhang,Gao-Yuan Wang,Dan Xu,Daniel Keifenheim,Alejandro Franco,Jose Cansado,Hirohisa Masuda,Nick Rhind,Yamei Wang,Quan-Wen Jin

Source: Journal of cell science

DNA replication timing

jueves, julio 11, 2013

Author(s): Nicholas Rhind,David M Gilbert

Source: Cold Spring Harbor perspectives in biology

Signaling pathways that regulate cell division

miércoles, octubre 03, 2012

Author(s): Nicholas Rhind,Paul Russell

Source: Cold Spring Harbor perspectives in biology

Genome-wide identification and characterization of replication origins by deep sequencing

jueves, abril 26, 2012

Author(s): Jia Xu,Yoshimi Yanagisawa,Alexander M Tsankov,Christopher Hart,Keita Aoki,Naveen Kommajosyula,Kathleen E Steinmann,James Bochicchio,Carsten Russ,Aviv Regev,Oliver J Rando,Chad Nusbaum,Hironori Niki,Pa...

Source: Genome biology

Replication timing and its emergence from stochastic processes

martes, abril 24, 2012

Author(s): John Bechhoefer,Nicholas Rhind

Source: Trends in genetics : TIG

Evolutionary divergence of intrinsic and trans-regulated nucleosome positioning sequences reveals plastic rules for chromatin organization

jueves, septiembre 15, 2011

Author(s): Alex Tsankov,Yoshimi Yanagisawa,Nicholas Rhind,Aviv Regev,Oliver J Rando

Source: Genome research

Studying S-phase DNA damage checkpoints using the fission yeast Schizosaccharomyces pombe

sábado, agosto 27, 2011

Author(s): Nicholas Willis,Nicholas Rhind

Source: Methods in molecular biology (Clifton, N.J.)

Studying G2 DNA damage checkpoints using the fission yeast Schizosaccharomyces pombe

sábado, agosto 27, 2011

Author(s): Nicholas Willis,Nicholas Rhind

Source: Methods in molecular biology (Clifton, N.J.)

Full-length transcriptome assembly from RNA-Seq data without a reference genome

martes, mayo 17, 2011

Author(s): Manfred G Grabherr,Brian J Haas,Moran Yassour,Joshua Z Levin,Dawn A Thompson,Ido Amit,Xian Adiconis,Lin Fan,Raktima Raychowdhury,Qiandong Zeng,Zehua Chen,Evan Mauceli,Nir Hacohen,Andreas Gnirke,Nichol...

Source: Nature biotechnology

Comparative functional genomics of the fission yeasts

sábado, abril 23, 2011

Author(s): Nicholas Rhind,Zehua Chen,Moran Yassour,Dawn A Thompson,Brian J Haas,Naomi Habib,Ilan Wapinski,Sushmita Roy,Michael F Lin,David I Heiman,Sarah K Young,Kanji Furuya,Yabin Guo,Alison Pidoux,Huei Mei Che...

Source: Science (New York, N.Y.)

Mre11 nuclease activity and Ctp1 regulate Chk1 activation by Rad3ATR and Tel1ATM checkpoint kinases at double-strand breaks

jueves, noviembre 25, 2010

Author(s): Oliver Limbo,Mary E Porter-Goff,Nicholas Rhind,Paul Russell

Source: Molecular and cellular biology

Modeling genome-wide replication kinetics reveals a mechanism for regulation of replication timing

viernes, agosto 27, 2010

Author(s): Scott Cheng-Hsin Yang,Nicholas Rhind,John Bechhoefer

Source: Molecular systems biology

Reconciling stochastic origin firing with defined replication timing

sábado, marzo 06, 2010

Author(s): Nicholas Rhind,Scott Cheng-Hsin Yang,John Bechhoefer

Source: Chromosome research : an international journal on the molecular, supramolecular and evolutionary aspects of chromosome biology

The fission yeast Rad32(Mre11)-Rad50-Nbs1 complex acts both upstream and downstream of checkpoint signaling in the S-phase DNA damage checkpoint

miércoles, enero 13, 2010

Author(s): Nicholas Willis,Nicholas Rhind

Source: Genetics

The role of specific checkpoint-induced S-phase transcripts in resistance to replicative stress

martes, septiembre 15, 2009

Author(s): Chaitali Dutta,Nicholas Rhind

Source: PloS one

Regulation of DNA replication by the S-phase DNA damage checkpoint

martes, julio 07, 2009

Author(s): Nicholas Willis,Nicholas Rhind

Source: Cell division

Incorporation of thymidine analogs for studying replication kinetics in fission yeast

miércoles, julio 01, 2009

Author(s): Nicholas Rhind

Source: Methods in molecular biology (Clifton, N.J.)

Changing of the guard: how ATM hands off DNA double-strand break signaling to ATR

martes, marzo 31, 2009

Author(s): Nicholas Rhind

Source: Molecular cell

The role of MRN in the S-phase DNA damage checkpoint is independent of its Ctp1-dependent roles in double-strand break repair and checkpoint signaling

viernes, febrero 13, 2009

Author(s): Mary E Porter-Goff,Nicholas Rhind

Source: Molecular biology of the cell

Mus81, Rhp51(Rad51), and Rqh1 form an epistatic pathway required for the S-phase DNA damage checkpoint

viernes, noviembre 28, 2008

Author(s): Nicholas Willis,Nicholas Rhind

Source: Molecular biology of the cell

The Hsk1(Cdc7) replication kinase regulates origin efficiency

viernes, septiembre 19, 2008

Author(s): Prasanta K Patel,Naveen Kommajosyula,Adam Rosebrock,Aaron Bensimon,Janet Leatherwood,John Bechhoefer,Nicholas Rhind

Source: Molecular biology of the cell

An intrinsic checkpoint model for regulation of replication origins

sábado, agosto 30, 2008

Author(s): Nicholas Rhind

Source: Cell cycle (Georgetown, Tex.)

The DNA replication checkpoint directly regulates MBF-dependent G1/S transcription

miércoles, julio 30, 2008

Author(s): Chaitali Dutta,Prasanta K Patel,Adam Rosebrock,Anna Oliva,Janet Leatherwood,Nicholas Rhind

Source: Molecular and cellular biology

Just-in-time DNA replication

martes, enero 01, 2008

Author(s): Suckjoon Jun,Nick Rhind

Source: Physics

DNA replication timing: random thoughts about origin firing

sábado, diciembre 02, 2006

Author(s): Nicholas Rhind

Source: Nature cell biology

Cdc2 tyrosine phosphorylation is not required for the S-phase DNA damage checkpoint in fission yeast

miércoles, noviembre 15, 2006

Author(s): Naveen Kommajosyula,Nicholas Rhind

Source: Cell cycle (Georgetown, Tex.)

Basic methods for fission yeast

sábado, febrero 25, 2006

Author(s): Susan L Forsburg,Nicholas Rhind

Source: Yeast (Chichester, England)

DNA replication origins fire stochastically in fission yeast

viernes, octubre 28, 2005

Author(s): Prasanta K Patel,Benoit Arcangioli,Stephen P Baker,Aaron Bensimon,Nicholas Rhind

Source: Molecular biology of the cell

A single Argonaute protein mediates both transcriptional and posttranscriptional silencing in Schizosaccharomyces pombe

viernes, septiembre 17, 2004

Author(s): Alla Sigova,Nicholas Rhind,Phillip D Zamore

Source: Genes & development

In vivo labeling of fission yeast DNA with thymidine and thymidine analogs

miércoles, mayo 26, 2004

Author(s): Sasirekha Sivakumar,Mary Porter-Goff,Prasanta K Patel,Kristen Benoit,Nicholas Rhind

Source: Methods (San Diego, Calif.)

The fission yeast Rad32 (Mre11)-Rad50-Nbs1 complex is required for the S-phase DNA damage checkpoint

viernes, agosto 29, 2003

Author(s): Charly Chahwan,Toru M Nakamura,Sasirekha Sivakumar,Paul Russell,Nicholas Rhind

Source: Molecular and cellular biology

DNA damage checkpoint control of mitosis in fission yeast

viernes, mayo 23, 2003

Author(s): N Rhind,B A Baber-Furnari,A Lopez-Girona,M N Boddy,J M Brondello,B Moser,P Shanahan,A Blasina,C McGowan,P Russell

Source: Cold Spring Harbor symposia on quantitative biology

Roles of the mitotic inhibitors Wee1 and Mik1 in the G(2) DNA damage and replication checkpoints

sábado, marzo 10, 2001

Author(s): N Rhind,P Russell

Source: Molecular and cellular biology

Checkpoints: it takes more than time to heal some wounds

jueves, enero 04, 2001

Author(s): N Rhind,P Russell

Source: Current biology : CB

Chk1 and Cds1: linchpins of the DNA damage and replication checkpoint pathways

miércoles, noviembre 01, 2000

Author(s): N Rhind,P Russell

Source: Journal of cell science

Regulation of mitotic inhibitor Mik1 helps to enforce the DNA damage checkpoint

miércoles, enero 19, 2000

Author(s): B A Baber-Furnari,N Rhind,M N Boddy,P Shanahan,A Lopez-Girona,P Russell

Source: Molecular biology of the cell

Child sexual abuse in Hong Kong: double victimization?

sábado, mayo 29, 1999

Author(s): N Rhind,T Leung,F Choi

Source: Child abuse & neglect

Mitotic DNA damage and replication checkpoints in yeast

sábado, enero 23, 1999

Author(s): N Rhind,P Russell

Source: Current opinion in cell biology

The Schizosaccharomyces pombe S-phase checkpoint differentiates between different types of DNA damage

miércoles, agosto 05, 1998

Author(s): N Rhind,P Russell

Source: Genetics

Tyrosine phosphorylation of cdc2 is required for the replication checkpoint in Schizosaccharomyces pombe

jueves, junio 25, 1998

Author(s): N Rhind,P Russell

Source: Molecular and cellular biology

Cdc25 mitotic inducer targeted by chk1 DNA damage checkpoint kinase

viernes, septiembre 05, 1997

Author(s): B Furnari,N Rhind,P Russell

Source: Science (New York, N.Y.)

Cdc2 tyrosine phosphorylation is required for the DNA damage checkpoint in fission yeast

sábado, febrero 15, 1997

Author(s): N Rhind,B Furnari,P Russell

Source: Genes & development

xol-1 acts as an early switch in the C. elegans male/hermaphrodite decision

viernes, enero 13, 1995

Author(s): N R Rhind,L M Miller,J B Kopczynski,B J Meyer

Source: Cell

A tumorigenic murine Sertoli cell line that is temperature-sensitive for differentiation

viernes, octubre 01, 1993

Author(s): K Boekelheide,J W Lee,S J Hall,N R Rhind,K S Zaret

Source: The American journal of pathology

Royal patronage and the hospital service

jueves, junio 02, 1977

Author(s): N Rhind

Source: Nursing mirror