Davis Laboratory

Roger J. Davis, MA, MPhil, PhD


Roger J. Davis received his BA and PhD from the Department of Biochemistry at Cambridge University (U.K.). He received a Damon Runyon-Walter Winchell Cancer Fund Fellowship to do postdoctoral work at the Department of Biochemistry and Molecular Biology at the University of Massachusetts Medical Center. He remained at the University of Massachusetts Medical School as a faculty member. He is an Investigator of the Howard Hughes Medical Institute and a Fellow of the Royal Society.

In May 2018, Dr. Davis was elected into the National Academy of Sciences (NAS), joining four UMass Medical School colleagues who have received membership in recognition of their distinguished and continuing achievements in original research.  Membership in the NAS is one of the highest honors bestowed upon a scientist in the United States. 

As a basic research faculty member in the Diabetes Center of Excellence, his work to explain the molecular mechanism by which inflammation contributes to diabetes, cancer and stroke has been among the most important in this field for more than two decades. Dr. Davis’ studies of stress signaling pathways have led to the discovery of new genes that contribute to the development of these devastating diseases.  His lab is currently studying the design of novel therapeutic strategies.

The goal of his laboratory is to understand the molecular mechanism by which growth factors and cytokines regulate cellular proliferation and survival. A specific focus of their research is to understand how MAP kinase signaling pathways, which are initiated at the cell surface, regulate the expression of genes in the nucleus.

UMass Profile