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Oliver J Rando

UMassMed Faculty Page


Title: A Process for Delivering Small RNAs to Sperm. UMMS16-37; Patent Pending. 

  • This invention provides methods to modulate transgenerational epigenetic inheritance, wherein some epigenetic phenotypes are maintained through generations. The disclosed method involves using epididymosomes, small vesicles found in the testis, to deliver RNA molecules to sperm, enabling tailored RNA delivery to the zygote upon fertilization. 


Innovation TopicsGene TherapyRNAi/micro-RNA TherapyReproductive biology