Oliver J Rando

UMassMed Faculty Page

Inventions:

Title: A Process for Delivering Small RNAs to Sperm. UMMS16-37; Patent Pending. 

• This invention provides methods to modulate transgenerational epigenetic inheritance, wherein some epigenetic phenotypes are maintained through generations. The disclosed method involves using epididymosomes, small vesicles found in the testis, to deliver RNA molecules to sperm, enabling tailored RNA delivery to the zygote upon fertilization. 

  • Technology: Gene Therapy, RNAi/micro-RNA Therapy
    
  • Applications: Reproductive biology

Innovation Topics: Gene Therapy, RNAi/micro-RNA Therapy, Reproductive biology