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  • Study shows neuron-glia crosstalk important factor in axon regeneration

    Study shows neuron-glia crosstalk important factor in axon regeneration

    This discovery that neurons promote axon regeneration by communicating with nearby glia cells may be useful to scientists designing new treatments for a variety of disorders, from spinal cord injury to traumatic brain injury.

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  • PhD candidate to use NIH award to study cell death in cancer patients

    PhD candidate to use NIH award to study cell death in cancer patients

    Nicholas Harper, a PhD candidate in the Interdisciplinary Graduate Program, has received a prestigious award from the National Cancer Institute to study cell death as it relates to cancer therapies.

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  • Prescribed fruits and veggies can improve health, UMass Chan researcher finds

    Prescribed fruits and veggies can improve health, UMass Chan researcher finds

    Kurt Hager, PhD, is the lead author of a study that found the health of people with diabetes, hypertension and obesity improved when a health care professional prescribed free fruits and vegetables.

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  • NIH funds Kirschstein Award recipient Johan Girgenrath’s fertility research

    NIH funds Kirschstein Award recipient Johan Girgenrath’s fertility research

    PhD candidate John Girgenrath has received a competitive award from the Eunice Kennedy Shriver National Institute of Child Health and Human Development to conduct fertility research.

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  • Kirschstein award to fund PhD candidate’s research on HTLV-1

    Kirschstein award to fund PhD candidate’s research on HTLV-1

    PhD candidate Sarah Zvornicanin has received an award from the National Institute of Allergy and Infectious Diseases to study HTLV-1, a retrovirus that can cause a type of cancer and a progressive nervous system condition.

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  • Munson lab receives NIH award for research on intracellular cargo transport

    Munson lab receives NIH award for research on intracellular cargo transport

    A $3.3 million grant will allow the Munson lab to study what happens in the specific point in time before vesicles are fused to the membrane in eukaryotic cells and discover how vesicle targeting and membrane fusion is achieved.

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  • AI-powered arm band to detect opioid use disorder, withdrawals in development at UMass Chan, URI

    AI-powered arm band to detect opioid use disorder, withdrawals in development at UMass Chan, URI

    Stephanie Carreiro, MD, PhD'22, is the lead investigator on the development of the MINDER system, which includes a wearable device, a mobile app and an online portal for clinicians to monitor medication use and withdrawals.

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  • UMass Chan BRIDGE Fund invests nearly $2M in 13 faculty projects

    UMass Chan BRIDGE Fund invests nearly $2M in 13 faculty projects

    The BRIDGE Fund supports critical research milestones for inventions and discoveries that have high potential to change the course of disease and continues to grow, increasing from approximately $1 million per year in 2019 to $3 million in 2024.

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  • Heart disease risk associated with electrocardiogram-estimated age

    Heart disease risk associated with electrocardiogram-estimated age

    A new study involving more than 9,000 Framingham Heart Study participants shows standard electrocardiograms can predict biological age and risk of cardiac disease and death.

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  • David Guertin’s study on brown fat as anti-obesity target published in Nature Metabolism

    David Guertin’s study on brown fat as anti-obesity target published in Nature Metabolism

    David Guertin studies brown fat and its correlation with protection resistance to metabolic diseases such as obesity, insulin resistance and fatty liver disease.

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  • Family connects with researchers behind Canavan gene therapy

    Family connects with researchers behind Canavan gene therapy

    Boston toddler Noa Greenwood, who was one of the first to receive an investigational gene therapy for Canavan disease developed at UMass Chan Medical School, delivered a very special “thank you” to the research team in a visit with her parents earlier this year.

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  • Zebrafish helpful models to study skin conditions like vitiligo and melanoma, UMass Chan scientist writes

    Zebrafish helpful models to study skin conditions like vitiligo and melanoma, UMass Chan scientist writes

    Craig Ceol, PhD, and his team recently discovered a new way in which melanocytes, a small subset of epidermal cells, regenerate. Dr. Ceol explains why zebrafish are good models to study melanocytes in this piece for The Conversation.

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  • New center will evaluate, accelerate technology to reduce suicide

    New center will evaluate, accelerate technology to reduce suicide

    The NIH-funded Center for Accelerating Practices to End Suicide through Technology Translation (CAPES) includes a network of organizations working with UMass Chan, including UMass Memorial Health, UMass Lowell, UMass Amherst, Worcester Polytechnic Institute, Zero Suicide Institute and more than 100 other collaborating institutions.

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  • Andrea Reboldi awarded Burroughs Wellcome Fund grant

    Andrea Reboldi awarded Burroughs Wellcome Fund grant

    Andrea Reboldi, PhD, was awarded a $500,000 grant for his research on the regulation of intestinal humoral immunity by cholesterol metabolites.

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  • Antisense therapy restores fragile X protein production in human cells

    Antisense therapy restores fragile X protein production in human cells

    An antisense therapy developed by Joel D. Richter, PhD, Sneha Shah, PhD, and Jonathan K. Watts, PhD, at UMass Chan Medical School and Elizabeth Berry-Kravis, MD, PhD, at RUSH University Medical Center, restores production of the protein FMRP in cell samples taken from patients with fragile X syndrome. 

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  • Transgender, gender-diverse patients face barriers to eating disorder care, UMass Chan survey finds

    Transgender, gender-diverse patients face barriers to eating disorder care, UMass Chan survey finds

    According to research by Katarina A. Ferrucci, PhD’23, transgender and gender-diverse people face more challenges than cisgender people in accessing treatment for eating disorders, and care providers aren’t always aware of the barriers.

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  • Roberto Caricchio launches Lupus Center at UMass Chan

    Roberto Caricchio launches Lupus Center at UMass Chan

    Roberto Caricchio, MD, is leading the new UMass Chan Lupus Center at UMass Chan in partnership with UMass Memorial Health.

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  • Using the microbiome to protect against radiation exposure

    Using the microbiome to protect against radiation exposure

    Beth McCormick, PhD, and Vanni Bucci, PhD, are leading a $3 million effort to explore engineering the gut microbiome to counteract the effects of radiation exposure and total body irradiation.

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  • Clinical study aims to identify early molecular and biological signatures of vitiligo

    Clinical study aims to identify early molecular and biological signatures of vitiligo

    John E. Harris, MD, PhD, and Manuel Garber, PhD, will lead a $3.75 million NIH clinical study at UMass Chan Medical School to identify potential preclinical genetic, molecular and biological signatures that may predispose patients to developing vitiligo.

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  • Jessica Spinelli named 2023 Searle Scholar

    Jessica Spinelli named 2023 Searle Scholar

    Jessica Spinelli, PhD, and members of her lab are leveraging the discovery of a new mammalian metabolite and mitochondrial pathway to develop tools to reprogram the electron transport chain.

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  • Josué Flores Kim receives Smith Family Award for Excellence in Biomedical Research

    Josué Flores Kim receives Smith Family Award for Excellence in Biomedical Research

    Josué Flores Kim, PhD, is one of five scientists to receive a 2023 Smith Family Award for Excellence in Biomedical Research from the Richard and Susan Smith Family Foundation.

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  • UMass Chan digital medicine study uses smart toilet seat to monitor heart health

    UMass Chan digital medicine study uses smart toilet seat to monitor heart health

    Researchers in UMass Chan Medical School’s Program in Digital Medicine are testing how a smart toilet seat can help patients with chronic diseases better manage their health.

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  • UMass Chan, Worcester County Jail to collaborate on substance use treatment program research

    UMass Chan, Worcester County Jail to collaborate on substance use treatment program research

    UMass Chan and the Worcester County Jail & House of Correction will use a $50,000 grant to study recidivism and medical data from several substance abuse treatment programs offered at the jail.

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  • UMass Chan faculty lead creation of perinatal mental health tools

    UMass Chan faculty lead creation of perinatal mental health tools

    Perinatal mental health conditions are the leading cause of maternal mortality or pregnancy-related death in the United States. UMass Chan researchers Nancy Byatt, DO, MS, MBA, and Tiffany Moore Simas, MD, MPH, MEd, have spearheaded creation of new resources to help obstetric care clinicians identify and care for patients with mental health conditions.

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  • PODCAST: UMass Chan experts discuss gut microbiome’s role in health

    PODCAST: UMass Chan experts discuss gut microbiome’s role in health

    In a new Voices of UMass Chan podcast, Ana Maldonado-Contreras, PhD, and Heidi Leftwich, DO, discuss their research on the role the gut microbiome plays in our overall health.

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  • UMass Chan research on knee replacement shows satisfaction varies by age

    UMass Chan research on knee replacement shows satisfaction varies by age

    A new study led by David Ayers, MD, found that while adult patients from all age groups reported improvements following total knee arthroplasty, patients 55 and younger were found to have less improvement in pain, function and quality of life following surgery compared with those 75 and older.

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  • Craig Ceol receives NIH grant to study melanocyte regeneration

    Craig Ceol receives NIH grant to study melanocyte regeneration

    Craig Ceol, PhD, has received a grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases to fund research on cellular and molecular regulators of melanocyte regeneration using zebrafish as a model.

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  • MD/PhD student using NIH award to study onset of Huntington’s disease

    MD/PhD student using NIH award to study onset of Huntington’s disease

    MD/PhD student Jillian Belgrad has received an award from the National Institute of Neurological Disorders and Stroke to study the pathology that drives the development of Huntington’s disease symptoms.  

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  • Terence R. Flotte appears on ‘Giants of Gene Therapy’ podcast

    Terence R. Flotte appears on ‘Giants of Gene Therapy’ podcast

    In a one-on-one interview, Terence R. Flotte shares what inspired him to pursue a career in medicine and what he’s learned in his role as provost and dean of the T.H. Chan School of Medicine at UMass Chan.

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  • UMass Chan best in New England for primary care education

    UMass Chan best in New England for primary care education

    The T.H. Chan School of Medicine at UMass Chan Medical School is best in New England and in the top 10 percent nationwide for primary care education according to the U.S News & World Report 2023-2024 Best Graduate Schools rankings.

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  • Gene linking circadian and circatidal rhythms is discovered in tiny crustacean

    Gene linking circadian and circatidal rhythms is discovered in tiny crustacean

    Scientists at UMass Chan Medical School and the Marine Biological Laboratory at Woods Hole have identified the first gene to play a crucial role in regulating circatidal behavior in the crustacean Parhyale hawaiensis. The study by Patrick Emery, PhD; Joshua Rosenthal, PhD; and colleagues demonstrates the first molecular link between circatidal and circadian clocks.

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  • Phillip Zamore elected to National Academy of Sciences

    Phillip Zamore elected to National Academy of Sciences

    Phillip D. Zamore, PhD, is one of 120 newly elected members of the National Academy of Sciences who were recognized for distinguished achievements in original research. Dr. Zamore is credited with identifying the biochemical machinery responsible for RNA silencing.

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  • Inaugural Finberg memorial award winners to present at Innate Immunity Day

    Inaugural Finberg memorial award winners to present at Innate Immunity Day

    The Program in Innate Immunity is hosting Innate Immunity Day 2023: Mechanisms and Consequences of Cell Death on May 10 in the Albert Sherman Center Auditorium in the Sherman Center from 11:30 a.m. to 5:30 p.m.

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  • Genomes from 240 mammals reveal what makes human genome unique

    Genomes from 240 mammals reveal what makes human genome unique

    An international team of researchers co-led by UMass Chan researcher Elinor Karlsson, PhD, has demonstrated how comparative genomics can not only shed light on how certain species achieve extraordinary feats, but also help scientists better understand the parts of our genome that are functional and how they might influence health and disease.

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  • Healthy Families & Kids study shows promise for preventing childhood obesity

    Healthy Families & Kids study shows promise for preventing childhood obesity

    A new study authored by UMass Chan Medical School researchers found that periodic community health worker meetings with parents improved weight, diet and physical activity among children in socioeconomically disadvantaged communities in Worcester.

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  • Katherine Fitzgerald, Phillip Zamore elected to American Academy of Arts & Sciences

    Katherine Fitzgerald, Phillip Zamore elected to American Academy of Arts & Sciences

    Katherine Fitzgerald, PhD, and Phillip D. Zamore, PhD, were elected to the American Academy of Arts & Sciences, which honors excellence and leaders from every field of human endeavor to examine new ideas, address issues of importance to the nation and the world, and work together to cultivate every art and science.

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  • LISTEN: How schools can help with pediatric asthma

    LISTEN: How schools can help with pediatric asthma

    In a new Voices of UMass Chan podcast, Michelle K. Trivedi, MD'09, MPH, discusses her research on how school-based asthma programs can improve outcomes for historically marginalized children.

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  • UMass Chan scientists deliver siRNA therapy to lung

    UMass Chan scientists deliver siRNA therapy to lung

    A multidisciplinary team of UMass Chan scientists has developed a technology for delivering siRNA molecules locally to lung tissue, providing the first evidence of a platform capable of delivering chemically modified siRNAs to the lungs nasally and achieving robust genetic silencing.

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  • PhD candidate aims to make gene therapy techniques safer

    PhD candidate aims to make gene therapy techniques safer

    PhD candidate Suk Namkung has lived on three continents. He aims to investigate and advance a new generation of gene therapy viral vectors.

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  • Athma Pai awarded NSF CAREER grant

    Athma Pai awarded National Science Foundation CAREER grant

    Athma A. Pai, PhD, was awarded a nearly $1 million CAREER grant from the National Science Foundation to use new high-throughput genomics approaches to study the regulation of mRNA splicing.

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  • Boston Marathon fitting tribute for families touched by ALS

    Boston Marathon a fitting tribute for families touched by ALS

    Sisters Ashley Craig and Lacey Foley joined the UMass ALS Cellucci Fund Boston Marathon team in memory of their grandmother. Brothers Dean and Zack Kennedy, PhD’19, are running on the Jake Kennedy ALS Fund team, in honor of their father.

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  • End AxD funds gene therapy research for Alexander disease

    End AxD funds gene therapy research for Alexander disease

    Jun Xie, PhD, and Guangping Gao, PhD, received funding from End AxD, a nonprofit organization dedicated to the research and treatment for Alexander disease, to investigate an RNA silencing gene therapy for the rare genetic central nervous system disorder.

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  • PhD candidate Kathleen Morrill receives Harold M. Weintraub Graduate Student Award

    PhD candidate Kathleen Morrill receives Harold M. Weintraub Graduate Student Award

    PhD candidate Kathleen Morrill received the 2023 Harold M. Weintraub Graduate Student Award for her work on canine behavioral genomics and its relevance to human genetics and psychiatric disorders.

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  • Ryan Logan receives inaugural NIH HEAL Initiative Director’s Trailblazer Award

    Ryan Logan receives inaugural NIH HEAL Initiative Director’s Trailblazer Award

    Ryan W. Logan, PhD, received the inaugural Helping to End Addiction Long-Term Initiative, or NIH HEAL Initiative, Director’s Trailblazer Award for his research into specific cell types in the brain involved in opioid use disorder, opioid dependence and withdrawal.

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  • UMass Chan presents ‘Celebration of Black Excellence’ for Black History Month

    UMass Chan presents ‘Celebration of Black Excellence’ for Black History Month

    UMass Chan Medical School celebrated Black History Month with a focus on the research of four of its Black scientists: Brain Lewis, PhD; Ayorkor Gaba, PsyD; MD/PhD student Zach Dyer; and Natalie Anumba, PhD.

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  • UMass Chan investigators identify new pattern recognition system that monitors disease-causing bacteria in C. elegans

    UMass Chan investigators identify new pattern recognition system that monitors disease-causing bacteria in C. elegans

    Read Pukkila-Worley, MD, identified a new mechanism to detect microbial infection that intercepts pathogen-derived signals of growth and virulence to assess the relative threat of virulent bacteria.

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  • Renowned geneticist is inaugural speaker for The Robert W. Finberg, MD, Memorial Lecture at UMass Chan

    Renowned geneticist is inaugural speaker for The Robert W. Finberg, MD, Memorial Lecture at UMass Chan

    Jean-Laurent Casanova, MD, PhD, a world-renowned geneticist and expert in the fields of innate immunity and immunology, is the inaugural speaker for The Robert W. Finberg, MD, Memorial Lecture on Thursday, March 23.

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  • Musically minded PhD candidate targets movement disorders through fruit flies

    Musically minded PhD candidate targets movement disorders through fruit flies

    PhD candidate Lucas Restrepo tackles movement disorders using fruit fly genetics and, in his spare time, plays the banjo.

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  • UMass Chan licensed siRNA chemistry to Aldena Therapeutics to develop therapies for dermatological diseases

    UMass Chan licensed siRNA chemistry to Aldena Therapeutics to develop therapies for dermatological diseases

    UMass Chan Medical School has licensed siRNA chemistries developed by Julia Alterman, PhD, to Aldena Therapeutics for clinical development for dermatological diseases.

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  • How frontotemporal dementia changes the brain

    How frontotemporal dementia changes the brain

    In a piece written for The Conversation, Fen-Biao Gao, PhD, talks about how frontotemporal dementia changes the brain and the research that is untangling its genetic causes.

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  • Molecular biologists Allan Jacobson and Lynne Maquat receive 2023 Gruber Genetics Prize

    Molecular biologists Allan Jacobson and Lynne Maquat receive 2023 Gruber Genetics Prize

    The 2023 Gruber Genetics Prize is being awarded to molecular biologists Allan Jacobson, PhD, of UMass Chan Medical School, and Lynne Maquat, PhD, of the University of Rochester School of Medicine and Dentistry.

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  • UMass Chan researchers explain risk of spread in novel gonorrhea strain

    UMass Chan researchers explain risk of spread in novel gonorrhea strain

    UMass Chan infectious disease researchers Sanjay Ram, MD, and Peter Rice, MD, say testing and surveillance for a novel strain of gonorrhea identified in Massachusetts last month is critical for reducing spread.

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  • LISTEN: Learn about risks of cytomegalovirus, a common prenatal infection, in new podcast

    LISTEN: Learn about risks of cytomegalovirus, a common prenatal infection, in new podcast

    Laura Gibson, MD’94, discusses cytomegalovirus in a new Voices of UMass Chan podcast.

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  • Juan Ding, OD, PhD, (left) and James Ledwith, MD, each holding an AI-assisted device being used in a pilot study to screen for diabetic retinopothy in a primary care setting.

    UMass Chan, AEYE Health researching use of AI-based retinal camera screenings in primary care practice

    Juan Ding, OD, PhD, and James Ledwith, MD, are working with Israeli-based AEYE Health on a pilot study testing a handheld, AI-assisted retinal camera to improve screening for diabetic retinopathy in a primary care setting.

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  • V. Craig Jordan to give inaugural lecture on cancer drug discovery at UMass Chan

    V. Craig Jordan to give inaugural lecture on cancer drug discovery at UMass Chan

    Breast cancer research pioneer V. Craig Jordan, PhD, will give the inaugural virtual lecture in a series on cancer drug discovery at UMass Chan Medical School on Thursday, Feb. 16.

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  • NeuShen Therapeutics funds ALS research at UMass Chan Medical School

    NeuShen Therapeutics funds ALS research at UMass Chan Medical School

    UMass Chan Medical School has signed a three-year sponsored research agreement with NeuShen Therapeutics Inc. to investigate a gene therapy treatment for amyotrophic lateral sclerosis. Jun Xie, PhD, and Guangping Gao, PhD, are leading the project for UMass Chan.

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  • UMass Chan Medical School licenses data processing and analysis technology to Via Scientific

    UMass Chan Medical School licenses data processing and analysis technology to Via Scientific

    UMass Chan Medical School has licensed the rights to develop and commercialize a bioinformatic software platform developed by UMass Chan researchers Alper Kucukural, PhD, and Manuel Garber, PhD, and colleagues in the UMass Chan Bioinformatics Core to Via Scientific Inc., in Cambridge

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  • Head shot of David Keener, Phd candidate in the Morningside Graduate School of Biomedical Sciences

    PhD candidate awarded NIH Kirschstein Award for research on Rett syndrome

    PhD candidate David Keener has received a National Institutes of Health grant to fund his research project on Rett syndrome, a genetic neurodevelopmental disease generally diagnosed in girls ages 6 to 18 months.

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  • LISTEN: Physician-scientist Jeremy Luban reflects on lessons learned from the COVID-19 pandemic

    LISTEN: Physician-scientist Jeremy Luban reflects on lessons learned from the COVID-19 pandemic

    Jeremy Luban, MD, discusses the latest SARS COV-2 variant of concern and the future of vaccines in the fight against COVID in a new Voices of UMass Chan podcast.

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  • Vivian Budnik named fellow of the American Association for the Advancement of Science

    Vivian Budnik named fellow of the American Association for the Advancement of Science

    Vivian Budnik, PhD, has been elected as a fellow of the American Association for the Advancement of Science for her contributions to the understanding of the mechanisms of synaptic signaling.

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  • Ana Rita Batista, PhD, (left) instructor in neurology, pictured with Miguel Sena-Esteves, PhD, associate professor of neurology and director of the Translational Institute for Molecular Therapeutics..

    UMass Chan researchers achieve gene therapy milestone for potential Cockayne syndrome treatment

    Researchers working with UMass Chan Medical School’s Translational Institute for Molecular Therapeutics announced progress in developing a vector to deliver gene replacement therapy in mice models with Cockayne syndrome, a rare and fatal neurodegenerative disease that largely affects children and young adults.

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  • Small pilot study explores addition of remote activity tracking to electronic health records

    Small pilot study explores addition of remote activity tracking to electronic health records

    The pilot project aims to determine if wearable devices can help the flow of patient data to electronic health records and give providers the opportunity to assist patients more effectively with weight management.

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  • Trio of UMass Chan researchers receive awards for studies on age-related macular degeneration

    Trio of UMass Chan researchers receive awards for studies on age-related macular degeneration

    Claudio Punzo, PhD; Johanna Seddon, MD, ScM; and Shun-Yun Cheng, PhD’22, are receiving awards from the American Macular Degeneration Foundation.

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  • UMass Chan neurobiologist Eviatar Yemini recognized with Hypothesis Fund award

    UMass Chan neurobiologist Eviatar Yemini recognized with Hypothesis Fund award

    Eviatar Yemini, PhD, was chosen to receive a seed grant from the Hypothesis Fund, an innovative, new nonprofit that relies on a network of scientist “scouts” to identify and recommend novel, early-stage research to fund.

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  • UMass Chan researchers contribute to study of drug prevalence among injured road users

    UMass Chan researchers contribute to study of drug prevalence among injured road users

    Kavita Babu, MD, was a co-author of a recent study from the National Highway Traffic Safety Administration on toxicological analyses of blood specimens from roadway users who were seriously or fatally injured in motor vehicle crashes.

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  • Susan Swain receives grant to explore harnessing B cells for a universal flu vaccine for older adults

    Susan Swain receives grant to explore harnessing B cells for a universal flu vaccine for older adults

    The goal of research by Susan Swain, PhD, is to ultimately provide a blueprint for a vaccine that would recognize evolving influenza strains and provide long-lasting immunity to people throughout the life cycle, particularly among older adults, whose immune responses become weaker as they age.

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  • UMass Chan licenses rights to spinal muscular atrophy gene therapy program to CANbridge Pharmaceuticals

    UMass Chan licenses rights to spinal muscular atrophy gene therapy program to CANbridge Pharmaceuticals

    UMass Chan Medical School has licensed the rights to develop and commercialize a novel second-generation gene therapy to treat spinal muscular atrophy developed by Jun Xie, PhD, Guangping Gao, PhD, and colleagues to global biopharmaceutical company CANbridge Pharmaceuticals Inc.

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  • UMass Chan to participate in pilot COVID-19 telehealth program Home Test to Treat launched by NIH

    UMass Chan to participate in pilot COVID-19 telehealth program Home Test to Treat launched by NIH

    UMass Chan Medical School will evaluate the NIH’s new Home Test to Treat program that will provide free COVID-19 health services—at-home rapid tests, telehealth sessions and at-home treatments—in selected communities across the country.

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  • UMass Chan researcher Jennifer Tjia leading NIH study examining equity in caregiving

    UMass Chan researcher Jennifer Tjia leading NIH study examining equity in caregiving

    Jennifer Tjia, MD, MSCE, was recently awarded a $4.1 million, five-year grant from the National Institutes of Health to study caregiver engagement in serious illness and the impact of structural barriers, including racism.

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  • Jillian Richmond mentoring Morehouse med student Sachi Desse in research aimed to reduce disparities in dermatology

    Jillian Richmond mentoring Morehouse med student Sachi Desse in research aimed to reduce disparities in dermatology

    With a grant from the Dermatology Foundation, Morehouse School of Medicine student Sachi Desse is researching cutaneous T cell lymphoma, with Jillian Richmond, PhD, as her mentor.

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  • UMass Chan researcher Anastasia Khvorova named 2022 National Academy of Inventors Fellow

    UMass Chan researcher Anastasia Khvorova named 2022 National Academy of Inventors Fellow

    Anastasia Khvorova, PhD, is one of 169 academic inventors selected as a 2022 fellow of the National Academy of Inventors.

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  • Listen: At-home COVID-19 tests explained in time for holiday gatherings

    Listen: At-home COVID-19 tests explained in time for holiday gatherings

    UMass Chan experts break down common questions regarding at-home COVID-19 tests in a new Voices of UMass Chan podcast.

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  • UMass Chan study finds increase in treatment for eating disorders among young people during pandemic

    UMass Chan study finds increase in treatment for eating disorders among young people during pandemic

    The COVID-19 pandemic saw a significant increase in the number of adolescents and young adults with eating disorders admitted to inpatient treatment as well as outpatient programs, according to a recent study led by Sydney M. Hartman-Munick, MD.

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  • PhD candidate seeks to develop first clinically approved antifungal vaccine

    PhD candidate seeks to develop first clinically approved antifungal vaccine

    PhD candidate Maureen Hester has experienced UMass Chan as an undergraduate intern, research laboratory technician and as a PhD student. Her research targets Cryptococcus neoformans, a fungal pathogen that can cause pneumonia and progress to meningitis.

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  • Nanobody treatment developed by MassBiologics shows promise for treating SARS-CoV-2 infection

    Nanobody treatment developed by MassBiologics shows promise for treating SARS-CoV-2 infection

    MassBiologics of UMass Chan Medical School develops novel nanobody as inhalable and affordable medicine against SARS-CoV-2 and emerging variants.

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  • Study led by UMass Chan clinical scientists provides evidence of protective link between oral microbiome, COVID

    Study led by UMass Chan clinical scientists provides evidence of protective link between oral microbiome, COVID

    Evan S. Bradley, MD, PhD and Vanni Bucci, PhD, of the Program in Microbial Dynamics at UMass Chan, established a link between the oral microbiome and COVID-19 in patients needing in-hospital respiratory support.

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  • National experts in academic medicine discuss Diversity Engagement Survey created at UMass Chan with AAMC

    National experts in academic medicine discuss Diversity Engagement Survey created at UMass Chan with AAMC

    The Diversity and Inclusion Office featured the second of a three-part speaker series on Tuesday, Oct. 25, on the Diversity Engagement Survey developed by UMass Chan Medical School in collaboration with the Association of American Medical College.

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  • Prestigious NIH Kirschstein Award to fund MD/PhD student’s research into impact of structural racism on health

    Prestigious NIH Kirschstein Award to fund MD/PhD student’s research into impact of structural racism on health

    MD/PhD student Zach Dyer, MPH, will use a three-year NIH grant to fine-tune the structural racism effect index he built for his thesis research and get it in front of policy makers.

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  • UMass Chan working with Evaxion to evaluate vaccine candidates for gonorrhea

    UMass Chan working with Evaxion to evaluate vaccine candidates for gonorrhea

    UMass Chan Medical School has received a National Institutes of Health grant for preclinical development of gonorrhea vaccine candidates identified by Denmark biotech company Evaxion.

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  • Interest in point-of-care technologies increases among health care professionals during pandemic

    Interest in point-of-care technologies increases among health care professionals during pandemic

    UMass Chan Medical School and UMass Lowell researchers report that interest among health care professionals in point-of-care technologies increased during the pandemic, based on results of identical surveys administered in late 2019 and late 2020.

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  • Gang Han and colleagues develop superfluorescence, light-emitting, nanocrystal alternative to lasers

    Gang Han and colleagues develop superfluorescence, light-emitting, nanocrystal alternative to lasers

    Researchers at UMass Chan Medical School and North Carolina State University have developed a superfluorescence crystal nanoparticle that uses near-infrared light to safely produce laser-quality light at room temperature.

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  • Eviatar Yemini honored with 2022 Klingenstein-Simons Fellowship Award in Neuroscience

    Eviatar Yemini honored with 2022 Klingenstein-Simons Fellowship Award in Neuroscience

    In his lab at UMass Chan Medical School, Eviatar Yemini, PhD, is working to develop a systems-biology model of a whole nervous system. Klingenstein-Simons Fellowship Awards support highly promising, early career scientists.

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  • UMass Chan BRIDGE Fund supports seven faculty projects with commercialization potential

    UMass Chan BRIDGE Fund supports seven faculty projects with commercialization potential

    BRIDGE Innovation and Business Development at UMass Chan Medical School has awarded $2.2 million to seven faculty-led biomedical research projects.

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  • Partnerships key to Medical School’s success, Chancellor tells Worcester Homecoming audience

    Partnerships key to Medical School’s success, Chancellor tells Worcester Homecoming audience

    Chancellor Michael F. Collins heralded the emergence of UMass Chan Medical School as both the state’s leading educator of primary care physicians and a research powerhouse in his June 9 keynote luncheon address for the inaugural Worcester Homecoming.

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  • Beyond COVID fatigue

    Beyond COVID fatigue

    Valerie Wedge, LICSW, CEAP, and director of the Office of Well-Being at UMass Chan Medical School, said her office is seeing more confusion, depression and anger than a year ago, when COVID fatigue made its way into conversation.

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  • New studies to test performance of home COVID-19 tests for omicron

    New studies to test performance of home COVID-19 tests for omicron

    UMass Chan Medical School researchers and their partners in the National Institutes of Health Rapid Acceleration of Diagnostics initiative are starting new studies to determine if the performance of at-home COVID-19 antigen tests currently on the market in the U.S. is affected by the omicron variant.

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  • UMass Chan develops model to help clinicians discuss COVID-19 vaccines with pregnant women

    UMass Chan develops model to help clinicians discuss COVID-19 vaccines with pregnant women

    A new training initiative funded by the CDC and developed at UMass Chan Medical School aims to help health care providers counsel patients who are hesitant about taking the COVID-19 vaccine while pregnant.

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  • Top story: UMass Medical School researchers to start trial of Moderna COVID-19 vaccine in teens

    Top story: UMass Medical School researchers to start trial of Moderna COVID-19 vaccine in teens

    UMass Medical School researchers are about to start enrolling adolescents ages 12 through 17 in a clinical trial to test the COVID-19 mRNA vaccine made by Moderna. (Originally published on Jan. 26, 2021)

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  • UMass Chan clinical trial shows antisense oligonucleotide safely suppresses mutant ALS gene in pilot human study

    UMass Chan clinical trial shows antisense oligonucleotide safely suppresses mutant ALS gene in pilot human study

    Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues have shown the ability to suppress mutant forms of an ALS gene in a single-patient pilot study.

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  • UMass Medical School researchers to evaluate treatment options for early COVID-19 infection

    UMass Medical School researchers to evaluate treatment options for early COVID-19 infection

    UMass Medical School is participating in the ACTIV-2 Outpatient Monoclonal Antibodies and Other Therapies Trial, which is evaluating investigational agents for treating early COVID-19.

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  • Roger Davis elected to American Academy of Arts & Sciences

    Roger Davis elected to American Academy of Arts & Sciences

    Roger J. Davis, PhD, FRS, has been elected a member of the American Academy of Arts & Sciences in recognition of his research on stress signaling pathways that are connected to a range of diseases, such as arthritis, cancer, stroke, heart disease and diabetes.

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  • UMass Medical School helps lead NIH RADx to accelerate new COVID test technologies

    UMass Medical School helps lead NIH RADx to accelerate new COVID test technologies

    The national effort to bring convenient, affordable and rapid testing technology for SARS-CoV-2 infection to market is moving full speed ahead. The $1.5 billion effort was launched a year ago, with UMass Medical School playing a major role in coordinating the push for fast, accessible COVID-19 testing.

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  • U.S. News & World Report ranks UMass Medical School 10th in the nation in primary care education

    U.S. News & World Report ranks UMass Medical School 10th in the nation in primary care education

    UMass Medical School ranks 10th nationwide in primary care by U.S. News & World Report in its annual rankings of the best graduate schools. The 2022 report also marks a rise for UMMS in research, this year ranking 45th, up two spots from the previous ranking.

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  • New study of oral therapy candidate indicates positive results for patients with mild-to-moderate COVID-19

    New study of oral therapy candidate indicates positive results for patients with mild-to-moderate COVID-19

    New research by Kaleido Biosciences, Inc., and UMass Medical School’s John P. Haran, MD, PhD, and Beth McCormick, PhD, shows that the company’s microbiome metabolic therapy candidate produced positive results in patients with mild-to-moderate COVID-19.

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  • Innovative neurosurgical technique used in Tay-Sachs gene therapy clinical trial

    Innovative neurosurgical technique used in Tay-Sachs gene therapy clinical trial

    Oguz Cataltepe, MD, describes the innovative neurosurgical procedure used to treat patients in the new clinical trial for a gene therapy targeting infantile Tay-Sachs and Sandhoff diseases.

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  • Breast and prostate cancer screenings dropped during COVID-19 pandemic, UMMS study finds

    Breast and prostate cancer screenings dropped during COVID-19 pandemic, UMMS study finds

    Breast and prostate cancer screenings declined rapidly in the early months of the COVID-19 pandemic compared with the same period a year earlier, according to a new study by UMass Medical School researchers working with Reliant Medical Group.

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  • First patient dosed in clinical trial of gene therapy for Tay-Sachs and Sandhoff diseases

    First patient dosed in clinical trial of gene therapy for Tay-Sachs and Sandhoff diseases

    Sio Gene Therapies announced that the first patient with infantile Tay-Sachs disease has been dosed in a Phase I/II trial evaluating AXO-AAV-GM2, an investigational gene therapy for the treatment of GM2 gangliosidosis, which causes Tay-Sachs and Sandhoff diseases. Miguel Sena-Esteves, PhD, is a principal scientist of the research program at UMMS.

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  • UMass Chan researchers track COVID virus changes, community spread, as part of surveillance network

    UMMS researchers track COVID virus changes, community spread, as part of surveillance network

    UMass Medical School researchers are working with a statewide network in partnership with the Broad Institute of MIT and Harvard and the U.S. Centers for Disease Control and Prevention to determine the extent of SARS-CoV-2 mutations in the Worcester area and what role they might play in community spread.

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  • UMass Medical School researchers to start trial of Moderna COVID-19 vaccine in teens

    UMass Medical School researchers to start trial of Moderna COVID-19 vaccine in teens

    UMass Medical School researchers are about to start enrolling adolescents ages 12 through 17 in a clinical trial to test the COVID-19 mRNA vaccine made by Moderna.

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  • A healthy microbiome builds a strong immune system that could help defeat COVID-19

    A healthy microbiome builds a strong immune system that could help defeat COVID-19

    In a piece written for The Conversation, Ana Maldonado-Contreras, PhD, explains why the army of microbes living inside your gut is essential for fighting off threats, including the virus that causes COVID-19.

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  • Researchers to study health care providers’ influence on COVID-19 vaccine acceptance

    Researchers to study health care providers’ influence on COVID-19 vaccine acceptance

    Kimberly Fisher, MD, and Kathleen Mazor, EdD, are preparing a study to evaluate ways for health care providers to talk with their patients about the new COVID-19 vaccines and support them in getting vaccinated.

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  • Student-led virtual wellness program provides companionship to older, hospitalized COVID patients

    Student-led virtual wellness program provides companionship to older, hospitalized COVID patients

    A new companionship wellness initiative at UMass Medical School is combating isolation and loneliness among COVID-19 patients 65 and older by having students virtually check in, comfort and emotionally support them at two Worcester hospitals.

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  • Robert Finberg details next steps for COVID vaccine

    Robert Finberg details next steps for COVID vaccine

    Robert W. Finberg, MD, a member of Gov. Charlie Baker’s COVID-19 Vaccine Advisory Group, explains the process of getting the population vaccinated that will play out in phases over the coming year.

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  • New study co-authored by MD/PhD student Benjamin Helfand shows frequent delirium in older COVID patients

    New study co-authored by MD/PhD student Benjamin Helfand shows frequent delirium in older COVID patients

    MD/PhD student Benjamin Helfand is co-first author on a study published in the Journal of American Medical Association Network Open that examines the frequency of COVID-19 positive older adults presenting to the emergency department with delirium.

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  • Women in Science: Ana Maldonado-Contreras pivots gut microbiome studies to tackle COVID-19

    Women in Science: Ana Maldonado-Contreras pivots gut microbiome studies to tackle COVID-19

    Ana Maldonado-Contreras, PhD, studies the gut microbiome and chronic disease, in particular inflammatory bowel disease, and is now working to understand how gut microbes can predispose patients to severe COVID complications.

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  • COVID-19 vaccine trial reports high effectiveness; UMass Medical School key enrollment site

    COVID-19 vaccine trial reports high effectiveness; UMass Medical School key enrollment site

    First results from a Pfizer and BioNTech Phase III messenger RNA COVID-19 vaccine trial, in which UMass Medical School is participating, show promising findings, with more than 90 percent effectiveness in preventing infection with the SARS-CoV-2 virus, the companies announced.

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  • Sarah Nicole Forrester, Ann Moormann awarded $2 million NCI SeroNet grant

    Sarah Nicole Forrester, Ann Moormann awarded $2 million NCI SeroNet grant

    Sarah Nicole Forrester, PhD, and Ann Moormann, PhD, MPH, are co-principal investigators on a new grant aimed at enhancing representation of Black and Hispanic people in SARS-CoV-2 immunology research through the use of storytelling.

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  • More than half of COVID-19 clinical trials exclude older adults, according to research co-authored by MD/PhD student Benjamin Helfand

    More than half of COVID-19 clinical trials exclude older adults, according to research co-authored by MD/PhD student Benjamin Helfand

    A research letter published in JAMA Internal Medicine, co-authored by UMass Medical School MD/PhD student Benjamin Helfand, reports that older adults were likely to be excluded from more than 50 percent of COVID-19 clinical trials and 100 percent of vaccine trials initiated early in the pandemic.

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  • UMass Chan researchers study attitudes toward potential COVID-19 vaccine

    UMMS researchers study attitudes toward potential COVID-19 vaccine

    As many as four in 10 adults would refuse or hesitate to get a COVID-19 vaccine, according to a national survey, results of which were published in the Annals of Internal Medicine. Study co-authors Kimberly Fisher, MD, and Kathleen Mazor, EdD, say the findings indicate that health education outreach would be necessary to achieve widespread uptake of a safe and effective vaccine.

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  • Boston Globe, CNN: UMass Medical School seeking to enroll diverse communities in COVID vaccine trial

    Boston Globe, CNN: UMass Medical School seeking to enroll diverse communities in COVID vaccine trial

    Robert Finberg, MD, spoke with the Boston Globe and CNN about measures UMass Medical School has taken to reach a diverse population as it recruits for its involvement in the Pfizer/ BioNTech vaccine trail for COVID-19.

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  • UMass Chan researcher co-directs project to enhance diversity in biomedical sciences workforce

    UMMS researcher co-directs project to enhance diversity in biomedical sciences workforce.

    Mary Munson, PhD, is co-directing a first-of-its-kind national program to enhance diversity in the academic biomedical workforce, funded by a $1.3 million, five-year grant from the National Institutes of Health.

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  • UMass Medical School announces participation and enrollment for vaccine trial candidate against COVID-19

    UMass Medical School announces participation and enrollment for vaccine trial candidate against COVID-19

    UMass Medical School is enrolling healthy volunteers to take part in a Phase II/III clinical trial testing whether a messenger RNA vaccine candidate can prevent infection with the virus that causes COVID-19.

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  • Genomic analysis reveals many species may be vulnerable to SARS-CoV-2

    Genomic analysis reveals many species may be vulnerable to SARS-CoV-2

    A new study from scientists at UMass Medical School and the University of California, Davis, reveals that humans are not the only species facing a potential threat from SARS-CoV-2, the novel coronavirus that causes COVID-19.

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  • National Institute on Aging grant aims to create roadmap for COVID-19 trials in nursing homes

    National Institute on Aging grant aims to create roadmap for COVID-19 trials in nursing homes

    Jerry Gurwitz, MD, is principal investigator of a grant to develop a roadmap for developing clinical trials networks to study COVID-19 in nursing homes, as residents comprise more than 40 percent of deaths attributed to the pandemic nationwide.

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  • UMass Medical School receives $100 million in NIH grants to lead push for fast, accessible COVID-19 tests

    UMass Medical School receives $100 million in NIH grants to lead push for fast, accessible COVID-19 tests

    UMass Medical School has been awarded grants totaling more than $100 million to coordinate the nationwide push for fast, accessible COVID-19 testing, playing a major role in the National Institutes of Health’s Rapid Acceleration of Diagnostics, or RADx, program.

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  • UMass research and development expenditures rise to record $684 million

    UMass research and development expenditures rise to record $684 million

    Research expenditures at the University of Massachusetts increased by $33 million in one fiscal year to a record high of $684 million in fiscal year 2019. At UMass Medical School, research expenditures rose by 2.7 percent to $281.51 million.

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  • Greater Worcester COVID-19 Community Health Survey underway

    Greater Worcester COVID-19 Community Health Survey underway

    UMass Medical School is conducting a community-facing survey in Worcester and six surrounding communities to assess how COVID-19 has affected ongoing day-to-day needs and help localities target relief efforts.

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  • Katherine Fitzgerald and Anastasia Khvorova named Harrington Scholars

    Katherine Fitzgerald and Anastasia Khvorova named Harrington Scholars

    The Harrington Discovery Institute at University Hospitals in Cleveland, Ohio, in collaboration with Morgan Stanley GIFT Cures, has chosen two UMass Medical School faculty members to receive Harrington Scholar Awards for Coronavirus.

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  • UMass Medical School and UMass Memorial create risk scoring tool to triage COVID-19 patients

    UMass Medical School and UMass Memorial create risk scoring tool to triage COVID-19 patients

    David McManus, MD, and MD/PhD candidate Apurv Soni developed a tool to predict risk of severe illness in COVID-19 patients.

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  • UMass Medical School researchers ramp up COVID-19 convalescent plasma study

    UMass Medical School researchers ramp up COVID-19 convalescent plasma study

    More than 100 critically ill COVID-19 patients in the UMass Memorial Health Care system have been treated with convalescent plasma through a UMass Medical School clinical trial led by Jonathan M. Gerber, MD.

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  • Virus-like particles developed for RSV may hold key to COVID-19 vaccine, UMMS researcher says

    Virus-like particles developed for RSV may hold key to COVID-19 vaccine, UMMS researcher says

    Trudy Morrison, PhD, is the featured speaker at the Hudson Hoagland Society’s 35th annual meeting, to be held virtually on Wednesday, May 20.

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  • Mass Consortium on Pathogen Readiness awards COVID-19 research funding to three UMass Medical School projects

    Mass Consortium on Pathogen Readiness awards COVID-19 research funding to three UMass Medical School projects

    Research into COVID-19 by UMass Medical School scientists Ann Moormann, PhD, MPH; Robert Finberg, MD; and Jeremy Luban, MD, is being funded by the Massachusetts Consortium on Pathogen Readiness.

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  • NIH invests in rapid innovation and development for COVID-19 testing

    NIH invests in rapid innovation and development for COVID-19 testing

    The Center for Advancing Point of Care Technologies, co-directed by David McManus, MD, at UMass Medical School, will perform a key role in a new National Institutes of Health initiative aimed at speeding innovation, development and commercialization of COVID-19 testing technologies.

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  • Telegram: Robert Finberg explains UMass Medical School role in promising COVID-19 drug trial

    Telegram: Robert Finberg explains UMass Medical School role in promising COVID-19 drug trial

    Thirty-one patients with severe COVID-19 were enrolled in the randomized, controlled trial of the drug remdesivir at UMass Memorial Medical Center’s University and Memorial campuses, overseen by lead investigator Robert W. Finberg, MD.

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  • Fujifilm announces a Phase II clinical trial of influenza antiviral drug for COVID-19

    Fujifilm announces a Phase II clinical trial of influenza antiviral drug for COVID-19

    Fujifilm Corporation announced the initiation of a Phase II clinical trial in the United States to evaluate the safety and efficacy of its antiviral drug Avigan for patients with COVID-19, in collaboration with Brigham and Women’s Hospital, Massachusetts General Hospital and UMass Medical School. Robert W. Finberg, MD, is the principal investigator for the UMMS site.

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  • UMass Medical School, GE Healthcare Life Sciences to establish viral vector manufacturing facility

    UMass Medical School, GE Healthcare Life Sciences to establish viral vector manufacturing facility

    UMass Medical School and GE Healthcare Life Sciences will establish a new, large-scale viral vector manufacturing facility, able to provide large quantities of high-quality recombinant adeno-associated virus vectors for preclinical research on the UMMS campus in Worcester.

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