Molecular Medicine Faculty

Located in Biotech Two:

Michael P. Czech, Ph.D.,Professor and Chair of Molecular Medicine

RNAi-based therapeutic strategies for inflammatory and metabolic diseases

Paul Clapham, Ph.D., Associate Professor

          HIV receptors and cellular tropisms

Craig Peterson, Ph.D., Professor and Vice Chair of Molecular Medicine

Regulation of gene expression

Victor R. Ambros, Ph.D., Professor

Molecular and genetic control of animal development; microRNA regulatory mechanisms

Michael Brehm, Ph.D., Assistant Professor

Silvia Corvera, M.D., Professor

Signal transduction and membrane trafficking

Roger Davis, Ph.D., Professor

Mechanisms by which growth factors regulate cellular proliferation

Stephen Doxsey, Ph.D., Professor

Mitotic and meiotic spindle assembly with an emphasis on centrosome structure, functions, and regulation

Dale Greiner, Ph.D., Professor

T cell development and regulation of autoimmune disorders

David Guertin, Ph.D., Assistant Professor

Signal transduction in development and cancer

Tony Ip, Ph.D., Associate Professor

Intestinal stem cells and tissue regeneration in Drosophila

David Lambright, Ph.D., Professor

Structural and molecular mechanisms of cell signaling and membrane trafficking

Jeremy Luban, M.D., Professor

          HIV-1 replication, pathogenesis, and immunity

Katherine Luzuriaga, M.D., Professor

Viral and immunopathogenesis of persistent viral infections

Rene Maehr, Ph.D., Assistant Professor

          Using stem cell approaches to model and understand human immune diseases

Craig Mello, Ph.D., Professor

Regulation of gene expression during early embryogenesis in C. elegans

Gary Ostroff, Ph.D., Research Professor

         Phagocytic cell-targeted glucan particle-based systems for siRNA/DNA,

         peptides/proteins/Mab/enzymes, and small molecule delivery

Gregory Pazour, Ph.D., Associate Professor

The role of the intraflagellar transport (IFT) proteins in eukaryotic ciliary assembly

Joel Richter, Ph.D., Professor

Translational control of meiosis, mitosis, and neuronal synaptic plasticity

Caterina Strambio De Castilla, Ph.D., Assistant Professor

              Live cell imaging of HIV-1 within infected cells

John Sullivan, M.D., Professor

Cellular and humoral immune responses to Epstein-Barr virus and human immunodeficiency virus

Amy Walker, Ph.D., Assistant Professor

How is transcriptional regulation of lipogenesis linked to diet and environment in C. elegans and mammals

Maria Zapp, Ph.D., Assistant Professor

Regulation of retroviral and cellular mRNA transport

Located in Biotech Four:

Craig Ceol, Ph.D., Assistant Professor

Genetic regulators of melanoma formation using the zebrafish

Kirsten Hagstrom, Ph.D., Assistant Professor

Chromosome structure and segregation during cell division

William Theurkauf, Ph.D., Professor

Mitosis and cell cycle regulation; actin organization and function; embryonic axis specification

UMass Mouse Phenotyping Center
Located in Biotech Five:

Program in Gene Function and Expression
Located in the Lazare Research Building:

Michael Green, M.D., Ph.D., Professor and Director, Program in Gene Function and Expression

Eukaryotic gene regulation and cancer molecular biology

Usha Acharya, Ph.D., Assistant Professor

Molecular genetics of lipid metabolism and signaling

Ingolf Bach, Ph.D., Associate Professor

Neuronal cell fate specification

Jennifer Benanti, Ph.D., Assistant Professor

Regulation of cell growth and division

Michael Brodsky, Ph.D., Assistant Professor

Regulation of Drosophila p53 and DNA damage-induced apoptosis

Lucio Castilla, Ph.D., Associate Professor

Genetics of leukemia, mouse models

Thomas Fazzio, Ph.D., Assistant Professor

Chromatin regulation in stem cells

Heinrich Gottlinger, M.D., Ph.D., Professor

Molecular Biology of HIV-1

Paul Kaufman, Ph.D. , Associate Professor

Assembly and Function of Eukaryotic Chromosomes

Nathan Lawson, Ph.D., Associate Professor

Determining the signals responsible for blood vessel development using zebrafish

Brian Lewis, Ph.D., Associate Professor

Molecular genetics of pancreatic and liver cancers

Heidi Tissenbaum, Ph.D., Associate Professor

Molecular mechanisms of aging in C.elegans

Eduardo Torres, Ph.D., Assistant Professor 
          Understanding how aneuploidy affects cellular physiology and metabolism

Marian Walhout, Ph.D., Associate Professor

Mapping transcription regulatory circuits in the nematode C.elegans

Yong-Xu Wang, Ph.D., Assistant Professor

Transcriptional control of energy metabolism and metabolic diseases by the nuclear receptor PPAR subfamily

Bioinformatics and Integrative Biology:

Manuel Garber, Ph.D., Associate Professor
          lincRNAs and their evolutionary history and the systematic dissection of the transcriptional regulation of the immune response