Mandon Lab Research

The research in the Mandon laboratory is devoted to understanding the role of mitochondria in neurodegeneration and in aging. Mitochondria are an early target during the onset of neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) Alzheimer’s, Parkinson’s, and Huntington’s diseases and mitochondrial damage contributes significantly to disease progression. Mitochondrial damage and dysfunction are also heavily involved in the aging process. Specifically, we are focused in two fundamental research areas. First, the determination of the early events that trigger mitochondrial damage and second, the elucidation of the mechanisms that underlie mitochondrial dysfunction in the pathogenesis of human neurodegenerative diseases and in the aging process 

Neurotherapeutics Institute
Biochemistry & Molecular Pharmacology
Profiles Page