BBS-821 Advanced Molecular & Cellular Immunology

   
   
           
Class # Date Topic/Class Description

2016 Instructor

2016 Paper
           
           
         BLOCK I: Innate Immunity    
      Block Director: Jun Huh    
1 9/13/16 T Overview of Block &  TLRs and Microbial Recognition  Egil Lien
TLR4/MD2/LPS structure
           
2 9/15/16 Th          Toll-like receptors I:Bridging versus Signaling Adapters   Read Pukkila-Worley

Kagan Trif/Endosome paper

 

 

            
3 9/20/16 T              Invertebrate Immunity Neal Silverman  Sara Cherry, Toll7 paper
           
4 9/22/16 Th              Innate lymphoid cells Jun Huh  Merad, Microbiota-dependent crosswalk bet. macrophages and ILC3
           
5 9/27/16 T Autoimmunity & Nucleic Acid Sensing Ann Rothstein  Stetson, interferon-dependent autoimmunity
           
 6  9/29/16 Th             The Inflammasome  Egil Lien  Kagan caspase-11 Science Paper
              

 

7

 

10/4/16

T Fungal Recognition & Signal Transduction  Stu Levitz

 Compartment-Specific and Sequential Role of MyD88 and CARD9

 

8

 

10/6/16

Th

  Assignment in lieu of Quiz 

Neal,  Egil, Read, Ann, Stu, Jun

Formulate a hypothesis based on material provided by instructors, and discuss in class.

           
      BLOCK II: Adaptive immunity    
      Block Director:  Francis Chan    

 

9

 

10/11/16

 

T

 An Overview of the block/Intro to research proposal: Components of good proposals

 F. Chan/ J. Kang  An overview of the block
10 10/13/16 Th     Mouse genetics [lecture]  F. Chan

 

Lecture

 

 

           
11 10/18/16

 T cell development

 Eric Huseby  
           
12 10/20/16  Th   B cell development  Rachel Gerstein  
           
13 10/25/16  T

Cell death in the immune system

Francis Chan

Yatim Main Paper

Yatim Supplement

Annual Review

14 10/27/16  Th

 Control of pathogenic self-reactive T cells 

Joonsoo Kang

http://www.nature.com/ni/journal/v11.html

Additional paper: CTLA-4  Kang

           
15 11/1/16  T     Mucosal immunity  Andrea Reboldi  
           
16 11/3/16  Th   Assignment presentation    
           
 17  11/8/16  T  Presentation of Student Hypothesis    
           
      Block III: Lymphocyte Network    
       Block Director: Robert Woodland    
18 11/10/16 Th      Germinal Centers-  

AN OVERVIEW OF THE BLOCK

           
19 11/15/16  T    Generation of memory B cells  

 

           
 20

11/17/16

 Th

Induction of broadly neutralizing protective antibody:

   
           

 21

11/22/16

 

 T

Systems Biology approach to vaccine development

 

 

 

           
  11/24/16        Thanksgiving  

 

           
22  11/29/16   T  Assymetric cell division in the germinal center    
              
           
           
      BLOCK IV: INFECTIOUS DISEASE/IMMUNE DISFUNCTION    
      Block Director:  Samuel Behar    
 23 12/1/16  Th  

Toll-Like receptors II: innate and adaptive immunity 

 

 

24  12/6/16 Infectious disease II: innate immunity & DNA viruses   

 

25  12/8/16 Th   Infectious disease I: Tuberculosis  

 

 26  12/13/16  T  Infectious disease III: Influenza  

 

 27 12/15/16  Th  Infectious disease III: Vaccines and viruses  

 

           RESEARCH PROPOSALS    
           Director: Joonsoo Kang    
  1/5/17 Th       Pre-presentation discussions with faculty advisors (optional)    
   1/10/17 T      Proposal Presentations Begin    
           
           
      Deadlines:    
      Proposal topic selection by Oct 13 or earlier    
      Proposal  hypothesis discussion on Nov 8    
      Final proposal: DEC 22    
▴ Back To Top
Section Menu To Top