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“This is an exciting time to be pursuing a career in medicine and applying to UMass Chan Medical School.”
Photo of Dean Flotte

About the dean

Terence R. Flotte, MD, is provost, dean and executive deputy chancellor of UMass Chan Medical School, the only public medical school in Massachusetts. Since joining UMass Chan in 2007, Dr. Flotte has forged a path of unprecedented growth and achievement for the research, education and academic missions of the campus. An internationally known scientist, Flotte has conducted research on cutting edge molecular therapeutics that led to the first successful gene transfer with adeno-associated virus (AAV) in animals and the first ever human trial of an AAV. He also led the first human recombinant AAV trials in alpha-1 antitrypsin deficiency and Tay-Sachs disease, with the latter showing promising clinical benefits. He is the author of more than 280 scholarly papers and his research has been funded by the National Institutes of Health and the Alpha One Foundation. Since 2015, Flotte has also been editor-in-chief of gene therapy’s oldest journal family, Human Gene Therapy. 

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News articles

  • UMass Chan licenses monoclonal antibody for seasonal prevention of Lyme disease to Tonix Pharmaceuticals

    UMass Chan licenses monoclonal antibody for seasonal prevention of Lyme disease to Tonix Pharmaceuticals

    UMass Chan Medical School has licensed worldwide rights to a long-lasting human monoclonal antibody that prevents Lyme disease to New Jersey-based Tonix Pharmaceuticals Holding Corp.  

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  • Chancellor Collins’ final Convocation address encourages optimism, determination

    Chancellor Collins’ final Convocation address encourages optimism, determination

    Four faculty members were honored with chancellor's medals at the annual Convocation and Investiture ceremony. 

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  • UMass Chan celebrates start of academic year with Convocation Week 2025

    UMass Chan celebrates start of academic year with Convocation Week 2025

    Festivities kick off on Friday, Sept. 5, with the T.H. Chan School of Medicine White Coat Ceremony.

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  • Phase I/II clinical study of gene therapy for GM2 gangliosidosis, including Tay-Sachs and Sandhoff diseases, shows encouraging results

    Phase I/II clinical study of gene therapy for GM2 gangliosidosis, including Tay-Sachs and Sandhoff diseases, shows encouraging results

    Clinical study of gene therapy for GM2 gangliosidosis, including Tay-Sachs disease, shows encouraging results

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  • Gov. Healey’s DRIVE initiative aims to infuse $400M into state’s research and innovation economy

    Gov. Healey’s DRIVE initiative aims to infuse $400M into state’s research and innovation economy

    Gov. Healey introduced the Discovery, Research & Innovation for a Vibrant Economy initiative.

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  • UMass Chan celebrates naming of Paul J. DiMare Center

    UMass Chan celebrates naming of Paul J. DiMare Center

    The special event included a tour and an unveiling of the donor acknowledgement plaque in the building’s main lobby.

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  • Highly accomplished faculty named to endowed chairs

    Highly accomplished faculty named to endowed chairs

    The University’s Board of Trustees voted to approve the establishment of six new endowed chairs, the appointment of faculty to five chairs, and the renaming of an existing chair.

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  • ‘A hope-filled moment’: UMass Chan celebrates Class of 2025

    ‘A hope-filled moment’: UMass Chan celebrates Class of 2025

    At the 52nd Commencement at UMass Chan on June 1, 265 degrees were presented.

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  • T.H. Chan School of Medicine Class of 2025 celebrated at annual breakfast

    T.H. Chan School of Medicine Class of 2025 celebrated at annual breakfast

    More than 30 awards were presented to graduating medical students and faculty members during the ceremony.

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