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Terence R. Flotte, MD, is the Celia and Isaac Haidak Professor in Medical Education, Dean of the School of Medicine and Provost and Executive Deputy Chancellor of the University of Massachusetts Medical School (UMMS). He is professor of Pediatrics and the Horae Gene Therapy Center.
An internationally known pioneer in human gene therapy, Dr. Flotte’s research has been continuously NIH funded for 24 years, and has resulted in over 250 peer-reviewed publications, which have been cited over 16,000 times. His focus is the development of recombinant viral vectors to deliver therapeutic genes and miRNA to treat diseases such as cystic fibrosis (CF), fatty acid oxidation disorders, and alpha-1 antitrypsin (AAT) deficiency. In 1995, he was Principal Investigator (PI) of the first human use of rAAV, a (CF) clinical trial, and in 2003 PI of the first rAAV intramuscular clinical trial, which began his history of Gene Therapy trials in AAT.
His awards include the 2005 Society for Pediatric Research’s E. Mead Johnson Award for Outstanding Scientific Contributions and induction into the Johns Hopkins Society of Scholars in 2013. He currently serves as Editor-in-Chief of the Human Gene Therapy family of journals.