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Seddon Lab- Macular Degeneration Center of Excellence
Department of Ophthalmology and Visual Sciences

Diseases we study:

  • Age-related macular degeneration (AMD)
  • Juvenile onset macular diseases- Stargardt disease, Best Disease
  • Macular Dystrophies


Our primary goal is to find the causes of these macular diseases, factors that play a role in developing them, and those which alter their rate of progression over time, in order to provide targets for new therapies to reduce the burden of visual loss.

Eligibility Criteria:

You may be eligible if you are affected with one of these macular problems at any age, or have a family history of one of these macular diseases even if you are not affected, as long as one of your affected family members participates. The more people in the family who participate, the better we are able to find the cause of the disease in families and individuals.

Study Protocol includes:

  • An eye exam with ocular imaging
  • Blood drawing
  • Questionnaires


For individuals who can travel to Worcester, Dr. Seddon sees patients at the

UMass Memorial Medical Center –Hahnemann Campus
281 Lincoln St., 3rd floor, Worcester, MA 01605

Call Lori or her colleagues at 508-334-4637 to arrange an appointment

Participants who cannot travel to Worcester:

The ocular exam and imaging can be done at another doctor’s office. The blood draw can be done off-site as well. This can be arranged by calling 1-800-219-9157.