Transitions, Risks, and Action in Coronary Events – Center for Outcomes Research and Education (TRACE-CORE) is a Center for Cardiovascular Outcomes Research funded by the National Heart Lung and Blood Institute (NHLBI) of the National Institutes of Health (NIH). We have recruited an observational cohort study of 2,300 patients hospitalized for acute coronary syndrome. Participants are followed for one year post-hospitalization via telephone interviews and for two years via medical record abstraction. The goal of TRACE-CORE is to illuminate the transition between hospital and home following an ACS and to identify potentially modifiable factors that influence longer-term outcomes. TRACE-CORE is also helping to develop the research careers of four early stage investigators.

For more information, please read the TRACE-CORE design and rationale paper: 


Principal Investigator: Catarina Kiefe, PhD, MD

Transitions Project PI: Jeroan Allison, MD, MScEpi 

Action Scores Project PI: Robert Goldberg, PhD

Early Stage Investigators: Milena Anatchkova, PhDDavid McManus, MD, MSCI;Jane Saczynski, PhDMolly Waring, PhD 

Senior Project Director: Richard McManus, MPP, MSW  Contact, 508-856-8073

Cohort Demographics

Male: 66% 
Female: 34% 
White: 76% 
African American/Black: 16%
More than one race: 4% 
Other Race: 3% 
Hispanic (any race): 3% 
Mean: 63.1 years 
Min: 29.0 years 
Max: 94.0 years 

Data Availability

Data Currently Available for Request

Interview data are available for the
following time points:

  • baseline (in-hospital)
  • 1-month post-discharge
  • 3-months post-discharge 

Baseline medical record review data are available for the UMass Memorial Medical Center sites only.

Data Request Process

All investigators wishing to use TRACE-CORE data must complete a paper proposal form that will be reviewed by the TRACE-CORE Publications and Presentations committee. Following approval of a paper proposal, instructions will be provided to the investigator for how to access the data. 

Link to paper proposal form 
Contact: Daniel Amante