Molecular Medicine Faculty
Located in the Molecular Medicine Building: (Two Biotech)
- Michael P. Czech, Ph.D., Professor and Chair Emeritus
Isadore and Fannie Foxman Chair of Medical Research
Gene silencing and editing as therapeutic strategies for diabetes - Roger Davis, Ph.D., Professor and
Vice Chair of Molecular Medicine
Mechanisms by which growth factors regulate cellular proliferation - Craig Peterson, Ph.D., Professor and Interim Chair
of Molecular Medicine
Regulation of gene expression - Victor R. Ambros, Ph.D., Silverman Professor
of Natural Sciences
Molecular and genetic control of animal development; microRNA regulatory mechanisms - Raffi Aroian, Ph.D., Professor
Parasitic Disease Mechanisms - Silvia Corvera, M.D., Professor
Signal transduction and membrane trafficking - Stephen Doxsey, Ph.D., Professor
Mitotic and meiotic spindle assembly with an emphasis on centrosome structure, functions, and regulation - Kevin E Fogarty, MS, Assistant Professor
Imaging Molecular and Cellular Dynamics with Light Microscopy in Living Cells - Paul Greer, Ph.D., Assistant Professor
Human Neurological Disorders - David Guertin, Ph.D., Associate Professor
Signal transduction in development and cancer - Tony Ip, Ph.D., Professor
Intestinal stem cells and tissue regeneration in Drosophila - David Lambright, Ph.D., Professor
Structural and molecular mechanisms of cell signaling and membrane trafficking - Jeremy Luban, M.D., Professor
HIV-1 replication, pathogenesis, and immunity - Katherine Luzuriaga, M.D., Professor
Viral and immunopathogenesis of persistent viral infections - Gary Ostroff, Ph.D., Professor
Phagocytic cell-targeted glucan particle-based systems for siRNA/DNA, peptides/proteins/Mab/enzymes, and small molecule delivery - Gregory Pazour, Ph.D., Professor
The role of the intraflagellar transport (IFT) proteins in eukaryotic ciliary assembly - Joel Richter, Ph.D., Professor
Translational control of meiosis, mitosis, and neuronal synaptic plasticity - Caterina Strambio De Castilla, Ph.D., Associate Professor
Dissecting the interplay between HIV-1 and infected human cells during viral entry - John Sullivan, M.D., Professor
Cellular and humoral immune responses to Epstein-Barr virus and human immunodeficiency virus - Amy Walker, Ph.D., Assistant Professor
How is transcriptional regulation of lipogenesis linked to diet and environment in C. elegans and mammals - William Theurkauf, Ph.D., Professor
Mitosis and cell cycle regulation; actin organization and function; embryonic axis specification
Located in the Albert Sherman Center:
- Dale Greiner, Ph.D., Professor and Co-Director Diabetes Center of Excellence
T cell development and regulation of autoimmune disorders - Michael Brehm, Ph.D., Associate Professor
Regulation of T cell activation and effector functions
- Craig Ceol, Ph.D., Assistant Professor
Genetic regulators of melanoma formation using the zebrafish - Rene Maehr, Ph.D., Associate Professor
Using stem cell approaches to model and understand human immune diseases
Program In Systems Biology:
Marian Walhout Ph.D., Professor and Co-Director
Mapping Transcription Regulatory Circuits in the Nematode C. elegans
Michael Lee, Ph.D., Assistant Professor
Cancer Systems Pharmacology
Amir Mitchell, Ph.D., Assistant Professor
Cellular Networks in Health and Disease-
from Robust Function to Catastrophic Failure
UMASS Mouse Phenotyping Center:
Jason Kim, Ph.D., Professor and Director, UMass Mouse Phenotyping Center
Role of inflammation in obesity, diabetes and cardiovascular complications
Bioinformatics and Integrative Biology:
Manuel Garber, Ph.D., Associate Professor
lincRNAs and their evolutionary history and the systematic dissection of the transcriptional regulation of the immune response
Elinor Karlsson, Ph.D., Assistant Professor
Understanding how the human genome works
Located in the Rose Gordon Building:
- Maria Zapp, Ph.D., Assistant Professor
Regulation of retroviral and cellular mRNA transport
Joint Faculty Appointments in Molecular Medicine:
RNA Therapeutics Institute:
(Located in the Albert Sherman Center)
Craig Mello, Ph.D., Professor and Co-Director, RNA Therapeutics Center
Regulation of gene expression during early embryogenesis in C. elegans
Anastasia Khvorova, Ph.D., Professor
Develop and characterize novel RNA chemistries to promote efficient oligonucleotide internalization and tissue distribution
Erik Sontheimer, Ph.D., Professor
Biology and mechanism of RNA-based gene regulation; CRISPR interference; RNA directed genone editing and gene control
Wen Xue, Ph.D., Assistant Professor
Mouse models of cancer. Use CRISPR genome editing to functionally dissect cancer mutations in liver and lung cancer
Department of Molecular, Cell and Cancer Biology
(Located in the Lazare Research Building)
- Michael Green, M.D., Ph.D., Professor and Chair, Department of Molecular, Cell and Cancer Biology
Eukaryotic gene regulation and cancer molecular biology - Usha Acharya, Ph.D., Assistant Professor
Molecular genetics of lipid metabolism and signaling - Ingolf Bach, Ph.D., Professor
Neuronal cell fate specification - Jennifer Benanti, Ph.D., Associate Professor
Regulation of cell growth and division - Michael Brodsky, Ph.D., Assistant Professor
Regulation of Drosophila p53 and DNA damage-induced apoptosis - Lucio Castilla, Ph.D., Professor
Genetics of leukemia, mouse models - Thomas Fazzio, Ph.D., Professor
Chromatin regulation in stem cells - Heinrich Gottlinger, M.D., Ph.D., Professor
Molecular Biology of HIV-1 - Paul Kaufman, Ph.D., Professor
Assembly and Function of Eukaryotic Chromosomes - Nathan Lawson, Ph.D., Professor
Determining the signals responsible for blood vessel development using zebrafish - Brian Lewis, Ph.D., Associate Professor
Molecular genetics of pancreatic and liver cancers - Heidi Tissenbaum, Ph.D., Professor
Molecular mechanisms of aging in C.elegans - Eduardo Torres, Ph.D., Assistant Professor
Understanding how aneuploidy affects cellular physiology and metabolism - Yong-Xu Wang, Ph.D., Associate Professor
Transcriptional control of energy metabolism and metabolic diseases by the nuclear receptor PPAR subfamily
Adjunct Professor:
Juleen R. Zierath, PhD., Professor
Integrative Physiology And Metabolism
Karolinska Institute
SE-171 77 Stockholm, Sweden