Molecular Medicine Faculty

Located in the Molecular Medicine Building: (Two Biotech)

Michael P. Czech, Ph.D., Professor and Chair Emeritus
Isadore and Fannie Foxman Chair of Medical Research

Gene silencing and editing as therapeutic strategies for diabetes
Roger Davis, Ph.D., Professor and
Vice Chair of Molecular Medicine

Mechanisms by which growth factors regulate cellular proliferation
Craig Peterson, Ph.D., Professor and Interim Chair
 of Molecular Medicine
Regulation of gene expression
Victor R. Ambros, Ph.D., Silverman Professor
of Natural Sciences

Molecular and genetic control of animal development; microRNA regulatory mechanisms
Raffi Aroian, Ph.D., Professor
Parasitic Disease Mechanisms
Silvia Corvera, M.D., Professor
Signal transduction and membrane trafficking
Stephen Doxsey, Ph.D., Professor
Mitotic and meiotic spindle assembly with an emphasis on centrosome structure, functions, and regulation
Kevin E Fogarty, MS, Assistant Professor
Imaging Molecular and Cellular Dynamics with Light Microscopy in Living Cells
Paul Greer, Ph.D., Assistant Professor
Human Neurological Disorders
David Guertin, Ph.D., Associate Professor
Signal transduction in development and cancer
Tony Ip, Ph.D., Professor
Intestinal stem cells and tissue regeneration in Drosophila
David Lambright, Ph.D., Professor
Structural and molecular mechanisms of cell signaling and membrane trafficking
Jeremy Luban, M.D., Professor
HIV-1 replication, pathogenesis, and immunity
Katherine Luzuriaga, M.D., Professor
Viral and immunopathogenesis of persistent viral infections
Gary Ostroff, Ph.D., Professor
Phagocytic cell-targeted glucan particle-based systems for siRNA/DNA, peptides/proteins/Mab/enzymes, and small molecule delivery
Gregory Pazour, Ph.D., Professor
The role of the intraflagellar transport (IFT) proteins in eukaryotic ciliary assembly
Joel Richter, Ph.D., Professor
Translational control of meiosis, mitosis, and neuronal synaptic plasticity
Caterina Strambio De Castilla, Ph.D., Associate Professor
Dissecting the interplay between HIV-1 and infected human cells during viral entry
John Sullivan, M.D., Professor
Cellular and humoral immune responses to Epstein-Barr virus and human immunodeficiency virus
Amy Walker, Ph.D., Assistant Professor
How is transcriptional regulation of lipogenesis linked to diet and environment in C. elegans and mammals
William Theurkauf, Ph.D., Professor
Mitosis and cell cycle regulation; actin organization and function; embryonic axis specification

Located in the Albert Sherman Center:

Dale Greiner, Ph.D., Professor and Co-Director Diabetes Center of Excellence
T cell development and regulation of autoimmune disorders
Michael Brehm, Ph.D., Associate Professor
Regulation of T cell activation and effector functions
Craig Ceol, Ph.D., Assistant Professor
Genetic regulators of melanoma formation using the zebrafish
Rene Maehr, Ph.D., Associate Professor
Using stem cell approaches to model and understand human immune diseases


Program In Systems Biology: 

Marian Walhout Ph.D., Professor and Co-Director
Mapping Transcription Regulatory Circuits in the Nematode C. elegans


Michael Lee, Ph.D., Assistant Professor
Cancer Systems Pharmacology

Amir Mitchell, Ph.D., Assistant Professor
Cellular Networks in Health and Disease-
from Robust Function to Catastrophic Failure

UMASS Mouse Phenotyping Center: 

Jason Kim, Ph.D., Professor and Director, UMass Mouse Phenotyping Center
Role of inflammation in obesity, diabetes and cardiovascular complications

Bioinformatics and Integrative Biology:

Manuel Garber, Ph.D., Associate Professor
lincRNAs and their evolutionary history and the systematic dissection of the transcriptional regulation of the immune response

Elinor Karlsson, Ph.D., Assistant Professor
Understanding how the human genome works


Located in the Rose Gordon Building:

Maria Zapp, Ph.D., Assistant Professor
Regulation of retroviral and cellular mRNA transport


Joint Faculty Appointments in Molecular Medicine:

RNA Therapeutics Institute:
(Located in the Albert Sherman Center)

Craig Mello, Ph.D., Professor and Co-Director, RNA Therapeutics Center
Regulation of gene expression during early embryogenesis in C. elegans

Anastasia Khvorova, Ph.D., Professor
Develop and characterize novel RNA chemistries to promote efficient oligonucleotide internalization and tissue distribution

Erik Sontheimer, Ph.D., Professor
Biology and mechanism of RNA-based gene regulation; CRISPR interference; RNA directed genone editing and gene control

Wen Xue, Ph.D., Assistant Professor
Mouse models of cancer. Use CRISPR genome editing to functionally dissect cancer mutations in liver and lung cancer

Department of Molecular, Cell and Cancer Biology
(Located in the Lazare Research Building)

Michael Green, M.D., Ph.D., Professor and Chair, Department of Molecular, Cell and Cancer Biology
Eukaryotic gene regulation and cancer molecular biology
Usha Acharya, Ph.D., Assistant Professor
  Molecular genetics of lipid metabolism and signaling
Ingolf Bach, Ph.D., Professor
Neuronal cell fate specification
Jennifer Benanti, Ph.D., Associate Professor
Regulation of cell growth and division
Michael Brodsky, Ph.D., Assistant Professor
Regulation of Drosophila p53 and DNA damage-induced apoptosis
Lucio Castilla, Ph.D., Professor
Genetics of leukemia, mouse models
Thomas Fazzio, Ph.D., Professor
Chromatin regulation in stem cells
Heinrich Gottlinger, M.D., Ph.D., Professor
Molecular Biology of HIV-1
Paul Kaufman, Ph.D., Professor
Assembly and Function of Eukaryotic Chromosomes
Nathan Lawson, Ph.D., Professor
Determining the signals responsible for blood vessel development using zebrafish
Brian Lewis, Ph.D., Associate Professor
Molecular genetics of pancreatic and liver cancers
Heidi Tissenbaum, Ph.D., Professor
Molecular mechanisms of aging in C.elegans
Eduardo Torres, Ph.D., Assistant Professor
Understanding how aneuploidy affects cellular physiology and metabolism
Yong-Xu Wang, Ph.D., Associate Professor
Transcriptional control of energy metabolism and metabolic diseases by the nuclear receptor PPAR subfamily

Adjunct Professor: 

Juleen R. Zierath, PhD., Professor
Integrative Physiology And Metabolism
Karolinska Institute
SE-171 77 Stockholm, Sweden