Molecular Medicine Faculty

Located in the Molecular Medicine Building: (Two Biotech)

Michael P. Czech, Ph.D., Professor and Chair of Molecular Medicine

Gene silencing and editing as therapeutic strategies for diabetes

Roger Davis, Ph.D., Professor and Vice Chair of Molecular Medicine

Mechanisms by which growth factors regulate cellular proliferation

Craig Peterson, Ph.D., Professor and Vice Chair of Molecular Medicine

Regulation of gene expression

Victor R. Ambros, Ph.D., Silverman Professor of Natural Sciences

Molecular and genetic control of animal development; microRNA regulatory mechanisms

Raffi Aroian, Ph.D., Professor

Parasitic Disease Mechanisms

Paul Clapham, Ph.D., Professor

HIV receptors and cellular tropisms

Silvia Corvera, M.D., Professor

Signal transduction and membrane trafficking

Stephen Doxsey, Ph.D., Professor

Mitotic and meiotic spindle assembly with an emphasis on centrosome structure, functions, and regulation

Kevin E Fogarty, MS, Assistant Professor

Imaging Molecular and Cellular Dynamics with Light Microscopy in Living Cells

David Guertin, Ph.D., Associate Professor

Signal transduction in development and cancer

Tony Ip, Ph.D., Professor

Intestinal stem cells and tissue regeneration in Drosophila

David Lambright, Ph.D., Professor

Structural and molecular mechanisms of cell signaling and membrane trafficking

Jeremy Luban, M.D., Professor

HIV-1 replication, pathogenesis, and immunity

Katherine Luzuriaga, M.D., Professor

Viral and immunopathogenesis of persistent viral infections

Ann Moorman, Ph.D., MPH, Associate Professor

Pediatric immunity to infectious diseases

Gary Ostroff, Ph.D., Research Professor

Phagocytic cell-targeted glucan particle-based systems for siRNA/DNA,
peptides/proteins/Mab/enzymes, and small molecule delivery

Gregory Pazour, Ph.D., Professor

The role of the intraflagellar transport (IFT) proteins in eukaryotic ciliary assembly

Joel Richter, Ph.D., Professor

Translational control of meiosis, mitosis, and neuronal synaptic plasticity

Caterina Strambio De Castilla, Ph.D., Assistant Professor

Dissecting the interplay between HIV-1 and infected human cells during viral entry

John Sullivan, M.D., Professor

Cellular and humoral immune responses to Epstein-Barr virus and human immunodeficiency virus

Amy Walker, Ph.D., Assistant Professor

How is transcriptional regulation of lipogenesis linked to diet and environment in C. elegans and mammals

William Theurkauf, Ph.D., Professor

Mitosis and cell cycle regulation; actin organization and function; embryonic axis specification

---

Located in the Albert Sherman Center:

Dale Greiner, Ph.D., Professor and Co-Director Diabetes Center of Excellence

T cell development and regulation of autoimmune disorders

Craig Ceol, Ph.D., Assistant Professor

Genetic regulators of melanoma formation using the zebrafish

Rene Maehr, Ph.D., Assistant Professor
Using stem cell approaches to model and understand human immune diseases

Michael Brehm, Ph.D., Assistant Professor

Regulation of T cell activation and effector functions

 

Program In Systems Biology: 

Marian Walhout Ph.D., Professor and Co-Director
Mapping Transcription Regulatory Circuits in the Nematode C. elegans

 

 

Michael Lee, Ph.D., Assistant Professor
Cancer Systems Pharmacology

UMASS Mouse Phenotyping Center: 

Jason Kim, Ph.D., Professor and Director, UMass Mouse Phenotyping Center
Role of inflammation in obesity, diabetes and cardiovascular complications

Bioinformatics and Integrative Biology:

Manuel Garber, Ph.D., Associate Professor
lincRNAs and their evolutionary history and the systematic dissection of the transcriptional regulation of the immune response

Elinor Karlsson, Ph.D., Assistant Professor

Understanding how the human genome works

 

---

 
Located in the Rose Gordon Building:

Maria Zapp, Ph.D., Assistant Professor

Regulation of retroviral and cellular mRNA transport

---

 

Joint Faculty Appointments in Molecular Medicine:

RNA Therapeutics Institute:
(Located in the Albert Sherman Center)

Craig Mello, Ph.D., Professor and Co-Director, RNA Therapeutics Center

Regulation of gene expression during early embryogenesis in C. elegans.

Anastasia Khvorova, Ph.D., Professor

Develop and characterize novel RNA chemistries to promote efficient oligonucleotide internalization and tissue distribution.

Erik Sontheimer, Ph.D., Professor

Biology and mechanism of RNA-based gene regulation; CRISPR interference; RNA directed genone editing and gene control

Wen Xue, Ph.D., Assistant Professor

Mouse models of cancer. Use CRISPR genome editing to functionally dissect cancer mutations in liver and lung cancer.

---

Department of Molecular, Cell and Cancer Biology
(Located in the Lazare Research Building)

Michael Green, M.D., Ph.D., Professor and Chair, Department of Molecular, Cell and Cancer Biology

Eukaryotic gene regulation and cancer molecular biology

Usha Acharya, Ph.D., Assistant Professor

Molecular genetics of lipid metabolism and signaling

Ingolf Bach, Ph.D., Professor

Neuronal cell fate specification

Jennifer Benanti, Ph.D., Assistant Professor

Regulation of cell growth and division

Michael Brodsky, Ph.D., Assistant Professor

Regulation of Drosophila p53 and DNA damage-induced apoptosis

Lucio Castilla, Ph.D., Associate Professor

Genetics of leukemia, mouse models

Thomas Fazzio, Ph.D., Professor

Chromatin regulation in stem cells

Heinrich Gottlinger, M.D., Ph.D., Professor

Molecular Biology of HIV-1

Paul Kaufman, Ph.D., Professor

Assembly and Function of Eukaryotic Chromosomes

Nathan Lawson, Ph.D., Professor

Determining the signals responsible for blood vessel development using zebrafish

Brian Lewis, Ph.D., Associate Professor

Molecular genetics of pancreatic and liver cancers

Heidi Tissenbaum, Ph.D., Professor

Molecular mechanisms of aging in C.elegans

Eduardo Torres, Ph.D., Assistant Professor

Understanding how aneuploidy affects cellular physiology and metabolism

Yong-Xu Wang, Ph.D., Assistant Professor

Transcriptional control of energy metabolism and metabolic diseases by the nuclear receptor PPAR subfamily