Selected Publications

2019

Yeast Sirtuin Family Members Maintain Transcription Homeostasis to Ensure Genome Stability.  Feldman JL, Peterson CL. Cell Rep. 2019 Jun 4;27(10):2978-2989.e5. doi: 10.1016/j.celrep.2019.05.009.  PMID: 31167142 [PubMed - in process]  (Paper)

Cognitive and Microbiome Impacts of Experimental Ancylostoma ceylanicum Hookworm Infections in Hamsters. Pan SC, Ward DV, Yin Y, Hu Y, Elfawal MA, Clark RE, Aroian RV.Sci Rep. 2019 May 27;9(1):7868. doi: 10.1038/s41598-019-44301-4. PMID: 31133690 [PubMed - in process] (Paper)

Pheromones and Nutritional Signals Regulate the Developmental Reliance on let-7 Family MicroRNAs in C. elegans.  Ilbay O, Ambros V.  Curr Biol. 2019 May 1. pii: S0960-9822(19)30432-4. doi: 10.1016/j.cub.2019.04.034. [Epub ahead of print] PMID: 31104929 [PubMed - as supplied by publisher] (Paper)

The Misshapen subfamily of Ste20 kinases regulate proliferation in the aging mammalian intestinal epithelium.  Li Q, Nirala NK, Chen HJ, Nie Y, Wang W, Zhang B, Czech MP, Wang Q, Xu L, Mao J, Ip YT. J Cell Physiol. 2019 May 1. doi: 10.1002/jcp.28756. [Epub ahead of print].  PMID: 31042012 [PubMed - as supplied by publisher] (Paper)

A highly expressed intestinal cysteine protease of Ancylostoma ceylanicum protects vaccinated hamsters from hookworm infection.  Noon JB, Schwarz EM, Ostroff GR, Aroian RV. PLoS Negl Trop Dis. 2019 Apr 22;13(4):e0007345. doi: 10.1371/journal.pntd.0007345. [Epub ahead of print]
PMID: 31009474 [PubMed - as supplied by publisher] (Paper)

Transient Kinetic Analysis of SWR1C-Catalyzed H2A.Z Deposition Unravels the Impact of Nucleosome Dynamics and the Asymmetry of Histone Exchange.  Singh RK, Fan J, Gioacchini N, Watanabe S, Bilsel O, Peterson CL.  Cell Rep. 2019 Apr 9;27(2):374-386.e4. doi: 10.1016/j.celrep.2019.03.035.  PMID: 30970243 [PubMed - in process] (Paper)

Trans-splicing of the C. elegans let-7 primary transcript developmentally regulates let-7 microRNA biogenesis and let-7 family microRNA activity. Nelson C, Ambros V.  Development. 2019 Feb 15. pii: dev.172031. doi: 10.1242/dev.172031. [Epub ahead of print].  PMID: 30770392  (Paper)

The C. elegans heterochronic gene lin-28 coordinates the timing of hypodermal and somatic gonadal programs for hermaphrodite reproductive system morphogenesis. Choi S, Ambros V.  Development. 2019 Feb 11. pii: dev.164293. doi: 10.1242/dev.164293. [Epub ahead of print] PMID: 30745431.  (Paper)

2018

Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines. 
McCauley SM, Kim K, Nowosielska A, Dauphin A, Yurkovetskiy L, Diehl WE, Luban J. Nat Commun. 2018 Dec 13;9(1):5305. doi: 10.1038/s41467-018-07753-2.
PMID: 30546110 [PubMed - indexed for MEDLINE] (Paper)

Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans. 
Dokshin GA, Ghanta KS, Piscopo KM, Mello CC.  Genetics. 2018 Nov;210(3):781-787. doi: 10.1534/genetics.118.301532. Epub 2018 Sep 13.  PMID: 30213854. (Paper)

Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine.
Ding W, Higgins DP, Yadav DK, Godbole AA, Pukkila-Worley R, Walker AK. PLoS Genet. 2018 Nov 28;14(11):e1007812. doi: 10.1371/journal.pgen.1007812. [Epub ahead of print] PMID: 30485261 [PubMed - as supplied by publisher].  (Paper)

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.
Oudelaar AM, Davies JOJ, Hanssen LLP, Telenius JM, Schwessinger R, Liu Y, Brown JM, Downes DJ, Chiariello AM, Bianco S, Nicodemi M, Buckle VJ, Dekker J, Higgs DR, Hughes JR. Nat Genet. 2018 Oct 29. doi: 10.1038/s41588-018-0253-2. [Epub ahead of print] PMID: 30374068 [PubMed - as supplied by publisher] (Paper)

Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.
Yurkovetskiy L, Guney MH, Kim K, Goh SL, McCauley S, Dauphin A, Diehl WE, Luban J.  Nat Microbiol. 2018 Oct 8. doi: 10.1038/s41564-018-0256-x. [Epub ahead of print].  PMID: 30297740.  (Paper)

CRISPR delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.
Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP.
J Biol Chem. 2018 Sep 6. pii: jbc.RA118.004554. doi: 10.1074/jbc.RA118.004554. [Epub ahead of print].  PMID: 30190322.  (Paper)

Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs.
Ambros, V, Ruvkun, G.  Genetics. 2018 Jul;209(3):651-673. doi: 10.1534/genetics.118.300291.   PMID:29967059  (Paper)

Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth.
Li Q, Nirala NK, Nie Y, Chen HJ, Ostroff G, Mao J, Wang Q, Xu L, Ip YT.  Dev Cell. 2018 May 21;45(4):433-449.e6. doi: 10.1016. PMID: 29754801.  (Paper)

Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.
Mir A, Alterman JF, Hassler MR, Debacker AJ, Hudgens E, Echeverria D, Brodsky MH, Khvorova A, Watts JK, Sontheimer EJ.  Nat Commun. 2018 Jul 6;9(1):2641. doi: 10.1038/s41467-018-05073-z.  PMID: 29980686  (Paper)

Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis.
Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Mol Metab. 2018 Jun 27. pii: S2212-8778(18)30518-0. doi: 10.1016/j.molmet.2018.06.014. [Epub ahead of print] PMID: 30005879.  (Paper)

Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling.
Neto A, Ceol CJ. Pigment Cell Melanoma Res. 2018 Jan;31(1):115-119. doi: 10.1111/pcmr.12610. Epub 2017 Oct 23. PMID: 28646617 [PubMed - indexed for MEDLINE].  (Paper)

Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors.
Malaby AW, Das S, Chakravarthy S, Irving TC, Bilsel O, Lambright DG. Structure. 2018 Jan 2;26(1):106-117.e6. doi: 10.1016/j.str.2017.11.019. Epub 2017 Dec 21. PMID: 29276036.  (Paper)

2012 - 2017 Publications