Selected Publications

 2018

Intron-containing RNA from the HIV-1 provirus activates type I interferon and inflammatory cytokines. 
McCauley SM, Kim K, Nowosielska A, Dauphin A, Yurkovetskiy L, Diehl WE, Luban J. Nat Commun. 2018 Dec 13;9(1):5305. doi: 10.1038/s41467-018-07753-2.
PMID: 30546110 [PubMed - indexed for MEDLINE] (Paper)

Melanoma-associated GRM3 variants dysregulate melanosome trafficking and cAMP signaling.
Neto A, Ceol CJ. Pigment Cell Melanoma Res. 2018 Jan;31(1):115-119. doi: 10.1111/pcmr.12610. Epub 2017 Oct 23. PMID: 28646617 [PubMed - indexed for MEDLINE].  (Paper)

Structural Dynamics Control Allosteric Activation of Cytohesin Family Arf GTPase Exchange Factors.
Malaby AW, Das S, Chakravarthy S, Irving TC, Bilsel O, Lambright DG. Structure. 2018 Jan 2;26(1):106-117.e6. doi: 10.1016/j.str.2017.11.019. Epub 2017 Dec 21. PMID: 29276036.  (Paper)

Stress-responsive and metabolic gene regulation are altered in low S-adenosylmethionine.
Ding W, Higgins DP, Yadav DK, Godbole AA, Pukkila-Worley R, Walker AK. PLoS Genet. 2018 Nov 28;14(11):e1007812. doi: 10.1371/journal.pgen.1007812. [Epub ahead of print] PMID: 30485261 [PubMed - as supplied by publisher].  (Paper)

Single-allele chromatin interactions identify regulatory hubs in dynamic compartmentalized domains.
Oudelaar AM, Davies JOJ, Hanssen LLP, Telenius JM, Schwessinger R, Liu Y, Brown JM, Downes DJ, Chiariello AM, Bianco S, Nicodemi M, Buckle VJ, Dekker J, Higgs DR, Hughes JR. Nat Genet. 2018 Oct 29. doi: 10.1038/s41588-018-0253-2. [Epub ahead of print] PMID: 30374068 [PubMed - as supplied by publisher]
(Paper)

Primate immunodeficiency virus proteins Vpx and Vpr counteract transcriptional repression of proviruses by the HUSH complex.
Yurkovetskiy L, Guney MH, Kim K, Goh SL, McCauley S, Dauphin A, Diehl WE, Luban J.  Nat Microbiol. 2018 Oct 8. doi: 10.1038/s41564-018-0256-x. [Epub ahead of print].  PMID: 30297740.  (Paper)

CRISPR delivery particles targeting nuclear receptor-interacting protein 1 (Nrip1) in adipose cells to enhance energy expenditure.
Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline RH, Kim JK, Czech MP.
J Biol Chem. 2018 Sep 6. pii: jbc.RA118.004554. doi: 10.1074/jbc.RA118.004554. [Epub ahead of print].  PMID: 30190322.  (Paper)

Neuronal modulation of brown adipose activity through perturbation of white adipocyte lipogenesis.
Guilherme A, Pedersen DJ, Henriques F, Bedard AH, Henchey E, Kelly M, Morgan DA, Rahmouni K, Czech MP. Mol Metab. 2018 Jun 27. pii: S2212-8778(18)30518-0. doi: 10.1016/j.molmet.2018.06.014. [Epub ahead of print] PMID: 30005879.  (Paper)

Recent Molecular Genetic Explorations of Caenorhabditis elegans MicroRNAs.
Ambros, V, Ruvkun, G.  Genetics. 2018 Jul;209(3):651-673. doi: 10.1534/genetics.118.300291.   PMID:29967059  (Paper)

Ingestion of Food Particles Regulates the Mechanosensing Misshapen-Yorkie Pathway in Drosophila Intestinal Growth.
Li Q, Nirala NK, Nie Y, Chen HJ, Ostroff G, Mao J, Wang Q, Xu L, Ip YT.  Dev Cell. 2018 May 21;45(4):433-449.e6. doi: 10.1016. PMID: 29754801.  (Paper)

Heavily and fully modified RNAs guide efficient SpyCas9-mediated genome editing.
Mir A, Alterman JF, Hassler MR, Debacker AJ, Hudgens E, Echeverria D, Brodsky MH, Khvorova A, Watts JK, Sontheimer EJ.  Nat Commun. 2018 Jul 6;9(1):2641. doi: 10.1038/s41467-018-05073-z.  PMID: 29980686
  (Paper)

2012 - 2017 Publications