Selected Publications

Selected publications shown with PMM Bioinformatics Core members as co-authors

  1. Shen Y, Cohen JL, Nicoloro SM, Kelly M, Yenilmez B, Henriques F, Tsagkaraki E, Edwards YJK, Hu X, Friedline R, Kim JK, Czech MP. CRISPR delivery particles targeting Nrip1 in adipose cells to enhance energy expenditure. Journal of Biological Chemistry. jbc. RA118.004554. 2018.
  2. Girnius N, Edwards YJK, Garlick DS, Davis RJ. Disruption of JNK signaling promotes the development of breast cancer. eLife.Jun 1;7. pii: e36389. doi: 10.7554/eLife.36389. 2018.
  3. Girnius N, Edwards YJK, Davis RJ. The cJun NH2-terminal kinase (JNK) pathway contributes to mouse mammary gland remodeling during involution. Cell Death and Differentiation. doi: 10.1038/s41418-018-0081-z. 2018.
  4. Venkatesan AM, Vyas R, Gramann A, Dresser K, Gujja S, Bhatnagar S, Chhangawala S, Gomes C, Xi HS, Lian CG, Houvras Y, Edwards YJK, Deng A, Green M, Ceol CJ. Ligand-activated BMP signaling inhibits cell differentiation and cell death to promote melanoma. Journal Clinical Investigation, 128(1):294-308, 2017.
  5. Sanchez-Gurmaches J, Tang Y, Jespersen NZ, Wallace M, Martinez Calejman C, Gujja S, Li H, Edwards YJK, Wolfrum C, Metallo CM, Nielsen S, Scheele C, Guertin DA. Brown Fat AKT2 Is a Cold-Induced Kinase that Stimulates ChREBP-Mediated De Novo Lipogenesis to Optimize Fuel Storage and Thermogenesis. Cell Metabolism, 27(1):195-209.e6, 2017.
  6. Fitzgibbons TP, Edwards YJK, Shaw P, Iskandar A, Ahmed M, Bote J, Shah T, Sinha S, Gerszten RE, Keaney JF, Zile M, Aurigemma GP. Activation of Inflammatory and Pro-thrombotic Pathways in Acute Stress Cardiomyopathy. Frontiers in Cardiovascular Medicine, 4:49, 2017.
  7. Vernia S, Edwards YJK, Han MS, Cavanagh-Kyros J, Barrett T, Kim JK and Davis RJ. An alternative splicing program promotes adipose tissue thermogenesis. Elife 5, pii: e17672, 2016.
  8. Mansur F, Ivshina M, Gu W, Schaevitz L, Gujja S, Edwards YJK, Richter JD. Gld2-catalyzed 3’ Mono-adenylation of miRNAs in the Hippocampus has no Detectable Effect on their Stability or on Animal Behavior. RNA, 22(10):1492-1499, 2016.
  9. Smulan L, Ding W, Freinkman E, Gujja S, Edwards YJK, Walker A. Cholesterol-Independent SREBP-1 Maturation Is Linked to ARF1 Inactivation. Cell Reports 16(1):9-18, 2016.
  10. Roth Flach RJ, Guo CA, Danai LV, Yawe JC, Gujja S, Edwards YJK, Czech MP. Endothelial MAP4K4 is critical for lymphatic vascular development and function. Molecular and Cellular Biology 36:1740-1749, 2016.