Welcome

Our lab’s research has consistently been focused on host-virus interactions, with the goal of identification and mechanistic determination of novel strategies that viruses employ to exploit host pathways or subvert host defense against viral infection. Our recent work has focused on discovery of novel viral dependency and restriction factors using CRSIPR/Cas9 in addition to the development of novel tools and reagents in these studies. Identification of these interactions, and deduction of their mechanism is essential to the development of novel therapeutics and a greater understanding of human biology. We are currently focused on SARS-CoV-2, Influenza, HIV, and HBV. If interested in joining the lab or for more information please contact me at william.mcdougall@umassmed.edu.