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Clinical trial examines IBD diet in third trimester of pregnancy

Scientists seek to reduce Crohn’s disease in mothers, infants

Date Posted: Tuesday, July 09, 2019

Researchers at UMass Medical School and Icahn School of Medicine at Mount Sinai are conducting a clinical trial to determine if an anti-inflammatory diet may reduce the risk of pregnant women with Crohn’s disease relapsing after child birth and of disease transmission to the baby.

The Modulating Early Life Microbiome through Prenatal Dietary Intervention in Crohn’s Disease trial (MELODY) will evaluate whether a noninvasive diet intervention called IBD Anti-Inflammatory Diet (IBD-AID) adhered to during the third trimester of pregnancy can beneficially shift the bacterial flora of the microbiome in mothers with Crohn’s disease and their babies.