Clinical & Population Health Research Courses

Laboratory rotations are defined periods of research experience under the direction of a faculty member. They are intended to familiarize the student with concepts and techniques in several areas of research and to assist the student in evaluating research laboratories and projects that might be developed into a dissertation project. The student will participate in an on-going research project; gain familiarity with concepts underlying the research; acquire a working knowledge of techniques used in the research; and write a report and present an oral summary of the results of the research.

Credits: 2-4

Course Director: Faculty member in whose lab student is working

Semester Offered: Fall, Spring

Last Taught: Taught every Fall and Spring semester

Building on basic skills in epidemiology and scientific research methods, this course will cover research design, including hypothesis development, measurement, and analysis. Students will explore methodological strengths of various quantitative and qualitative techniques and designs. Students will have three examinations, weekly problem sets and assignments to develop original research approaches to specific scientific and clinical questions.

Credits: 3

Prerequisites: CTS605A or equivalent or permission from course coordinator 

Course Director: William Jesdale

Semester Offered: Fall

Last Taught: Fall 2022

The purpose of this class is to learn advanced epidemiologic techniques, to learn how and when to apply them, and to learn to design rigorous epidemiologic studies.  Students will gain experience in reading the primary epidemiologic methods literature. Course objectives will be met through class lecture, class discussion, problem sets, exams, application of selected principles to one’s research and the development of a mini-lecture.

Credits: 3

Prerequisites: CTS602A, CTS603A, CTS603B (corequisite) 

Course Director: Anthony Nunes

Semester Offered: Spring

Last Taught: Spring 2023

This course provides an overview of multivariable analysis and advanced analytical strategies for clinical and population health research. Emphasis is on developing an understanding of multivariable modeling in the context of linear, logistic and Poisson regression. Computational lab assignments and two exams will be completed.

Credits: 4

Prerequisites: CTS605A, Introduction to Statistics or permission from course coordinator 

Course Director: Austin Lee

Semester Offered: Spring

Last Taught: Spring 2023

Course provides a foundation for statistical thinking in clinical and population health research involving time to event data and longitudinal data. Students will learn statistical models used for estimation and inference; understand advanced statistical techniques; and develop modeling strategies and analysis plans for specific research questions.

Credits: 4

Prerequisites: CTS603A

Course Director: Jonggyu Baek

Semester Offered: Spring

Last Taught: Spring 2022

This course will provide structure and support for students completing their first major evaluation milestone.  Students come to the first day of class with a research study question approved by their mentor and an existing dataset to use to evaluate the study question. Students will develop a manuscript and write it up according to the instructions for authors for the target journal. Students will conduct their own data analysis and will be evaluated on summative competencies expected to be achieved by the end of their first year of CPHR core coursework and research experiences.  Students present their work in an open forum in the form of a 10-15 minute presentation followed by questions and answers. The manuscripts are sent out for review by three faculty.  Students have two weeks to write a rebuttal and prepare a revised manuscript.

Credits: 4

Prerequisites: CTS602A&B, CTS603A&B, CTS702

Course Director: Shao-Hsien Liu

Semester Offered: Summer

Last Taught: Summer 2023

This course reviews basic principles of epidemiology, investigation of disease outbreaks, and the application of various observational and experimental research designs and strategies to clinical, epidemiological, and translational research. Didactic instruction, readings, and problem sets (including lab-based analyses) are utilized to more fully understand epidemics and their causes, as well as various study designs including cross-sectional studies, case-control studies, cohort designs, and randomized clinical trials. Students also will learn how to design surveillance systems and develop and evaluate screening and diagnostic tests. Students are graded on in-class participation and two writing assignments (write-up of lab exercise and in-class student presentation). This is a full semester course with a total of 30 contact hours.

Credits: 3

Course Director: Austin Lee

Semester Offered: Fall

Last Taught: Fall 2022

Students will learn how to: create and sustain cohesive research teams; develop a productive program of research; develop good mentor and mentee relationships; engage in transdisciplinary science; understand the NIH Roadmap; and hear about different forms of clinical and community research from local investigators who conduct it. 

Course Director: Stephenie Lemon

Semester Offered: Spring

Last Taught: Summer 2021

The course considers the scientific and practical considerations in the design and conduct of observational studies and clinical trials. Topics to be covered include: study designs (cohort studies, case-control studies and clinical trials); confounding and bias; ethical considerations; patient recruitment and retention; interim analysis and safety monitoring; and analysis and reporting. Course objectives will be met through a combination of lecture, discussion and development of a proposal in the student’s area of interest.

Credits: 3

Prerequisites: CTS605A or permission from instructor 

Course Director: Bruce Barton

Semester Offered: Spring

Last Taught: Spring 2023

This course teaches students how to develop a peer reviewed scientific manuscript, through the review of elements of style, authorship and extent of information that needs to be incorporated into a scientific research paper. Students will learn how to develop the elements that go into a successful scientific manuscript, submit an article for peer review and respond to reviewers' concerns. During each session, students will critique the work of others enrolled in the course to obtain hands on experience in the write-up of the introduction, methods, results and discussion sections of a manuscript. This course will also teach students how to put together a successful oral, as well as poster, scientific presentation.

Credits: 3

Course Director: Robert Goldberg

Semester Offered: Fall, Spring, Summer

Last Taught: Spring 2023

The purpose of this class is to teach students how to conduct a systematic review, including development of a question of appropriate scope and clinical relevance; development of abstraction tool; selection of articles; and drafting of all sections of the review, including tables and figures. The end product will be a journal style and length systematic review in the topic area of the student’s substantive interest area that is 75 percent ready for submission to a peer-reviewed journal. 

Credits: 2

Course Director: Shao-Hsien Liu

Semester Offered: Fall

Last Taught: Fall 2022

This course is designed to provide students with a basic knowledge of ethics that will prepare them to understand and address problems in the ethical conduct of research involving human subjects, as well as understand and address scientific misconduct, including fraud, misrepresentation and conflict of interest. The course also addresses authorship guidelines, IRB regulations and UMass Chan Medical School Regulations. Students will also focus on how to design ethical research and evaluate treatment risk, placebo control, ethics of recruitment, dilemmas of informed consent, potential scientific contribution and issues for special populations and conducting research internationally. 

Credits: 2

Course Director: Catherine Dube

Semester Offered: Fall

Last Taught: Fall 2022

Course will cover a focused set of issues in advanced epidemiology such as conducting community based, surveillance-based randomized controlled trial. Skills will be developed in the practical and scientific issues as well as analysis plans and presentation of results.

Credits: 3

Prerequisites: CTS602A, CTS602B, CTS603A, CTS603B, or permission from instructor

Course Director: Sarah Forrester

Semester Offered: Spring

Last Taught: Spring 2023

This course will cover an advanced topic in biostatistics (for example, longitudinal data analysis, survival analysis, graphical information systems and spatial statistics). The purpose of the course is to provide students with emersion in one particular area of biostatistics, providing the theoretical background necessary and the practical hands-on data-analyze experience.

Credits: 3

Prerequisites: CTS603A, CTS603B or permission from instructor 

Course Director: Kate Lapane

Semester Offered: Summer

Last Taught: Has not been taught within last two years

This advanced methods course is focused on learning methods for addressing confounding and bias. The goals for students taking this course are: to become comfortable recognizing and discussing bias and confounding; to gain experience in using a variety of techniques that help in identifying and minimizing bias and confounding; and to be able to assess the potential impact of residual bias and confounding on study results. This course is organized as topic lectures followed by applications of the topic. Students independently apply what is introduced in the lecture to their own data and share their learning with classmates. 

Credits: 3

Prerequisites: CTS602A, CTS602B, CTS603A, CTS603B

Course Director: Anthony Nunes

Semester Offered: Spring

Last Taught: Spring 2023

The purpose of this course is to provide opportunities for the student to understand the foundations of randomized clinical trials (RCTs) in behavioral medicine research. Topics related to theory, design, implementation, and evaluation of behavioral randomized clinical trials will be discussed. Students will develop a research project where concepts can be applied and practice reviewing behavioral RCTs in the published literature.

Credits: 2

Prerequisites: CTS702 or permission from instructor

Course Director: Catherine Dube

Semester Offered: Spring

Last Taught: Spring 2020

This course focuses on examining and analyzing the concept of health literacy, with an emphasis on the relationship of health literacy to one’s ability to manage and optimize their health. The association of health literacy to health disparities and health outcomes will be explored. Challenges in conducting health literacy research and challenges inherent in providing quality care to those with limited health literacy will be examined. Evidence-based individual and organizational approaches to mitigate the effects of limited health literacy will be addressed.

Credits: 3

Course Director: Nancy Morris

Semester Offered: Summer

Last Taught: Has not been taught within last two years

This course provides an in-depth look at the U.S. health care system. Students will apply constructs of structure, process, and outcomes of care to understanding and evaluating health care quality and cost, and learn how health care policies and payment practices impact the accessibility, effectiveness and cost of care. 

Credits: 2

Course Director: Kate Lapane

Semester Offered: Fall, odd years

Last Taught: Fall 2021

The course will discuss fundamental concepts in chronic disease epidemiology; common research methods used in the design and conduct of studies of chronic disease epidemiology; and the application of these methods for the major chronic diseases affecting industrialized countries. Topics will include cardiovascular disease, cancer, cerebrovascular disease, diabetes and lifestyle practices to promote health.

Credits: 2

Prerequisites: CTS605A or permission from instructor 

Course Director: Mara Epstein

Semester Offered: Fall, odd years

Last Taught: Fall 2021

Students will become familiar with existing population-based public health, electronic medical record and claims data. Topics include advantages and disadvantages, complex sampling and weighting, and obtaining limited-access data. Using a population-based dataset, students will develop and implement an analytic plan to answer a research question of their choosing.

Credits: 2

Prerequisites: At least one semester each of epidemiology and biostatistics or permission of the course director

Course Director: ShaoHsien Liu

Semester Offered: Spring, even years

Last Taught: Spring 2022

This course will provide students with fundamental knowledge of psychiatric epidemiology. We will cover epidemiological principles specific to psychiatric epidemiology such as assessment and diagnostic validity in the absence of a gold standard. Students will be given the opportunity to conduct original research and will gain knowledge of particular psychiatric illnesses through student preparation of course presentations.

Credits: 2

Prerequisites: At least one semester each of epidemiology and biostatistics or permission of the course director

Course Director: Mayra Tisminetzky

Semester Offered: Spring

Last Taught: Spring 2023

We will cover the main societal causes implicated in affecting the health of human populations, including class hierarchy, racism, gender hierarchy, heteronormativity and ableism. We will focus on methodological approaches to measuring and interpreting these forces and their effects, on both minority and dominant populations.

Credits: 2

Prerequisites: CTS 605A or permission of the instructor

Course Director: William Jesdale

Semester Offered: Fall, even years

Last Taught: Fall 2022

The purpose of this class is to learn models of disease prevention; multilevel determinants of health behaviors; and major theories of health behavior change and their application to interventions to address major public health problems. 

Credits: 2

Course Director: Milagros Rosal

Semester Offered: Fall, even years

Last Taught: Has not been taught within last two years

This course examines use of qualitative methods in qualitative studies or mixed-qualitative/quantitative studies. Essential qualitative research components are explored: theory, rigor, research questions, data collection methods, writing open-ended questions, sampling, data coding and analysis (with a focus on thematic analysis in health research), publishing and writing proposals. Students apply concepts covered in class by developing an original qualitative study.

Credits: 2

Course Director: Catherine Dube

Semeter Offered: Spring, odd years

Last Taught: Spring 2023

The purpose of this class is to learn pharmacoepidemiology, including: rigorous methodologic approaches to the measurement of medication exposure, adherence and adverse events; pharmacoepidemiologic study design; choices for pharmacoepidemiology data resources; and the role of quality of life measurements and pharmacoeconomics.

Credits: 2

Prerequisites: CTS 602A or equivalent

Course Directors: Matthew Alcusky and Anthony Nunes

Semester Offered: Summer, odd years

Last Taught: Spring 2022

In this class, we will explore the influence of place on population health, including physical environment (e.g., air, water, soil, food), built environment (e.g., neighborhood structure, traffic, green space), social environment (e.g., cohesion, safety, deprivation, segregation), and legal and civic structure (e.g., policy, law, representation). We will also learn to implement (and critique) methodologic approaches that are particularly adapted to understanding how individuals and places interact, specifically multilevel thinking and modeling, and spatial analytic methods. 

Credits: 2

Prerequisites: CTS 602A or equivalent

Course Director: William Jesdale

Semester Offered: Summer, Fall, odd years

Last Taught: Fall 2021

This class provides an introduction to what is often referred to as translational, dissemination or implementation research, as well as the broad field of implementation science. Students will learn about the significance and major initiatives associated with moving research into practice, and will be introduced to conceptual and analytic tools (e.g., theories, frameworks) to support work in this area.

Credits: 2

Course Directors: Jamie Faro and Daniel Amante

Semester Offered: Fall

Last Taught: Spring 2022

This class builds on the foundation offered in CTS 735 regarding salient concepts and theories in the field of implementation science to examine key issues in the design and conduct of implementation research. Students will learn about prominent study designs that characterize many implementation trials, the important role that formative assessment plays in informing implementation efforts, and the issues inherent in identifying and measuring appropriate implementation processes and outcomes. 

Credits: 2

Prerequisites: CTS 735 or instructor permission

Course Directors: Timothy Hogan

Semester Taught: Spring

Last Taught: Has not been taught within last two years

The purpose of an independent study elective is to gain in depth knowledge of a specific topic by working closely with a faculty member with expertise in that area. Typically independent studies cover areas not addressed in the core curriculum and advanced topics or other electives. However, the level of effort and objectives for an independent study must be equivalent to that of a regular three-credit course. The student and sponsoring faculty member must propose a framework and outcome for the independent study, in the semester prior to the semester in which the student will be enrolled, to the program director for prior approval. 

Credits: 1-6

Prerequisites: Permission of associate dean for CPHR & course coordinator 

Course Director: Varies

Semester Offered: Fall, Spring, Summer

Last Taught: Spring 2023

Research rotations are defined periods of research experience under the direction of a faculty member. They are intended to familiarize the student with the theory, background, concepts and techniques in several areas of research and to assist the student in evaluating projects and areas that might be developed into a dissertation project. The student will participate in an ongoing research project; gain familiarity with a field of study; acquire a working knowledge of techniques used in the research; and write a report and make an oral presentation on the results of their work. 

Credits: 4

Course Director: Student's advisor

Semester Offered: Fall, Spring, Summer

Last Taught: Taught every semester

This course number is used for students sitting for the written qualifying exam—an evaluation milestone typically conducted in Spring of their second year of graduate study. 

Credits: 1

Course Director: Kate Lapane

Semester Offered: Spring, Summer

Last Taught: Taught every year

This course number is used for students who will defend their dissertation proposal. Students should register for this either in the Spring or Summer of their second year of graduate studies. 

Credits: 1

Course Director: Kate Lapane

Semester Offered: Spring, Summer

Last Taught: Taught every year

All graduate students are required to have a TRAC meeting each academic year in the Fall . After passing their Qualifying Exam in January of the second year and the Thesis Proposal Defense in the Spring or Summer of second year, students are required to register for this course each Fall semester until their Dissertation Examination Committee is formed.

Credits: 1

Course Director: Kate Lapane

Semester Offered: Fall Spring

Last Taught: Course taught every year

This course is for students who have selected a program and thesis advisor but who have not yet passed their Qualifying Examination.

Credits: 3-9

Course Director: Student's thesis advisor

Semester Offered: Fall, Spring, Summer

Last Taught: Taught every semester

The purpose of this course is to allow CPHR PhD students to gain experience writing grant proposals in a systematic fashion under faculty guidance. The course includes overviews of the grant process, participation in a mock proposal review session, and the completion of each of the written scientific components of proposals. 

Credits: 3

Prerequisites: CTS702, CTS602A, CTS 602B, CTS603A, CTS603B or permission of instructor

Course Director: Mara Epstein

Semester Offered: Spring

Last Taught: Spring 2023

Students register for Thesis Research after passing a Qualifying Examination. They will take Thesis Research each semester until they have accumulated 90 credits.

Credits: 7-12

Course Director: Student's thesis advisor

Semester Offered: Fall, Spring, Summer

Last Taught: Taught every semester

Students register for Graduate Research after completing the requisite number of credits to meet graduation requirements. They will take this course each semester until they complete all remaining requirements.

Credits: 0

Course Director: Student's thesis advisor

Semester Offered: Fall, Spring, Summer

Last Taught: Taught every semester

This course presents evidence based teaching theories, strategies and skills for individuals interested in the role of faculty in programs preparing students for health professions. Contemporary issues and approaches to educating students with diverse learning needs will be addressed from assessment of learning styles to evaluation of outcomes.  Societal influences on the curriculum development process are highlighted along with strategies for enhancing academic career development.

Credits: 3

Course Director: Maureen Wassef

Semester Offered: Spring

Last Taught: Has not been taught within last two years

This course is designed to provide students with an in-depth study of major qualitative designs and methods used to build substantive knowledge in nursing.  Emphasis is placed upon experiential learning of methods and techniques to design studies along with analysis and interpretation of data.

Credits: 3

Course Director: Donna Perry

Semester Offered: Fall

Last Taught: Has not been taught within last two years

This course focuses on survey methods, measurement theory and the processes of instrument evaluation, refinement and development. There will be an emphasis on the interaction of conceptual, methodological, cultural and pragmatic considerations that are essential to understand when measuring variables among clinical populations. Topics include survey design; scale development, item construction, psychometric evaluation of scales, data collection procedures and sampling strategies.

Credits: 3

Course Directors: James Fain and Sybil Crawford

Semester Offered: Fall

Last Taught: Fall 2022

This course builds on prior course work in qualitative methods and places specific emphasis on interviewing skills, participant observation, data management and data analysis. The process for intricately managing and iteratively analyzing qualitative data to allow descriptive and useful emergent latent or manifest findings that are congruent with the study purpose and aims will be discussed. Special attention will be paid to re-presenting data findings including oral and written presentation of qualitative findings as well as ethical considerations. There will be opportunities to have hands-on practice in conducting data management and analysis with differentiation among several qualitative approaches.

Credits: 3

Course Director: Susan Lynn Sullivan-Bolyai

Semester Offered: Summer

Last Taught: Summer 2020