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Selected Publications

Koupenova M, Corkrey HA, Vitseva O, Manni G, Pang CJ, Clancy L, PhD, Yao C, Rade J, Levy D, Wang JP, Finberg RW, Kurt-Jones EA, Freedman JE.  The Role of Platelets in Mediating a Response to Human Influenza Infection.  Nature Communications. 2019. 6;10(1):1780.

Shah RV, Hwang S-J, Yeri A, Tanriverdi K, Pico AR, Yao C, Murthy V, Ho J, Vitseva O, Iafrati MD, Levy D, Freedman JE.  Proteins altered by surgical weight loss highlight biomarkers of insulin resistance in the community. Arteriosclerosis, Thrombosis, and Vascular Biology. 2019:39(1):107-115.

Giraldez M , Spengler R, Etheridge A, Godoy P, Barczak A, Srinivasan S, De Hoff P, Tanriverdi K, Courtright A, Lu S, Khoory J, Rubio R, Baxter D, Driedonks T, Buermans H, Nolte-'t Hoen E, Jiang H, Wang K, Ghiran I, Wang Y, Van Keuren-Jensen K, Freedman JE, Woodruff P, Laurent L, Erle D, Galas D. Comprehensive multi-center assessment of accuracy, reproducibility and bias of small RNA-seq methods for quantitative miRNA profiling. Nature Biotechnology.  2018. 36(8):746-757.

Shah RV, Ziegler O, Liu X, Xiao C, Yeri A, Tanriverdi K, Rong J, Larson M,. Pico AR, Huan T, Levy D, Rosenzweig A, Vasan RS, Das S, Freedman JE Circulating extracellular RNAs, myocardial remodeling, and heart failure.  JAMA Cardiology.  2018. 3(9):871-876. 

Shah R, Patel, T, Freedman JE.  Plasma Extracellular Vesicles in Human Disease: A New Frontier in Medicine.  New England Journal of Medicine, 2018;379(10):958-966.

Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, Levy D, Freedman JE. Genome-wide identification of microRNA expression quantitative trait loci. Nature Commun. 2015 Mar 20;6:6601. doi: 10.1038/ncomms7601.PubMed PMID: 25791433; PMCID: PMC4369777.  

Freedman JE, Gerstein M, Mick E, Rozowsky J, Levy D, Kitchen R, Das S, Shah R, Danielson K, Beaulieu L, Navarro FCP, Wang Y, Galeev TR, Holman A,, Kwong RY, Murthy V, Tanriverdi SE, Koupenova-Zamor M, Mikalev E, Tanriverdi K.Diverse Human Extracellular RNAs are Widely Detected in Human Plasma.  Nature Commun. 2016; 7:11106c.  PMCID: PMC4853467.

KoupenovaM, VitsevaO, MacKayCR, BeaulieuL, Benjamin EJ, Mick E, Kurt-JonesEA, Ravid K, Freedman JE. Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis.  Blood. 2014 Jul 31;124(5):791-802. PMCID: PMC4118487. 

Risitano A, Beaulieu LM, Vitseva O, Freedman JE.  Platelets and platelet-like particles mediate intercellular RNA transfer. Blood. 2012, Jun 28;119(26):6288-95.PMCID: PMC3383198.

Freedman JE, Larson MG, Tanriverdi K, O’Donnell CJ, Morin K, Hakanson AS, Vasan RS, Johnson AD, Iafrati MD, Benjamin EJ.  The Relation of Platelet and Leukocyte Inflammatory Transcripts to Body Mass Index in the Framingham Heart Study.  Circulation. 2010, 3;122(2):119-29.  PMCID: PMC2910759.