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Selected Publications

Shah R, Patel, T, Freedman JE.  Plasma Extracellular Vesicles in Human Disease: A New Frontier in Medicine.  New England Journal of Medicine, 2018, in press. 

Shah RV, Ziegler O, Liu X, Xiao C, Yeri A, Tanriverdi K, Rong J, Larson M,. Pico AR, Huan T, Levy D, Rosenzweig A, Vasan RS, Das S, Freedman JE. Circulating extracellular RNAs, myocardial remodeling, and heart failure.  JAMA Cardiology. 2018.  In press.  

Clancy L, Beaulieu LM, Tanriverdi K, Freedman JE. The role of RNA uptake in platelet heterogeneity Thromb Haemost. 2017 May 3;117(5):948-961

Shah R, Murthy V, Danielson K, Pacold, M, Tanriverdi K, Larson MG, Hanspers K, Pico A, Zhang A, Wang, Mick M, Reis J, de Ferranti S, Freinkman E, Levy D, Hoffmann U, Osganian S, Das S, Freedman JE. Extracellular RNAs are associated with insulin resistance and metabolic phenotypes. Diabetes Care. 2017;40:546-553.  PMCID:  PMC5360281 

Huan T, Rong J, Liu C, Zhang X, Tanriverdi K, Joehanes R, Chen BH, Murabito, JM, Yao C,

Courchesne P, Munson PJ, O'Donnell CJ, Cox N, Johnson AD, Larson MG, Levy D, Freedman JE. Genome-wide identification of microRNA expression quantitative trait loci. Nature Commun. 2015 Mar 20;6:6601. doi: 10.1038/ncomms7601.PubMed PMID: 25791433; PMCID: PMC4369777.  

Freedman JE, Gerstein M, Mick E, Rozowsky J, Levy D, Kitchen R, Das S, Shah R, Danielson K, Beaulieu L, Navarro FCP, Wang Y, Galeev TR, Holman A,, Kwong RY, Murthy V, Tanriverdi SE, Koupenova-Zamor M, Mikalev E, Tanriverdi K.. Diverse Human Extracellular RNAs are Widely Detected in Human Plasma.  Nature Commun. 2016; 7:11106c.  PMCID: PMC4853467 

KoupenovaM, VitsevaO, MacKayCR, BeaulieuL, Benjamin EJ, Mick E, Kurt-JonesEA, Ravid K, Freedman JE. Platelet-TLR7 mediates host survival and platelet count during viral infection in the absence of platelet-dependent thrombosis.  Blood. 2014 Jul 31;124(5):791-802. PMCID: PMC4118487. 

Risitano A, Beaulieu LM, Vitseva O, Freedman JE.  Platelets and platelet-like particles mediate intercellular RNA transfer. Blood. 2012, Jun 28;119(26):6288-95.PMCID: PMC3383198 

Freedman JE, Larson MG, Tanriverdi K, O’Donnell CJ, Morin K, Hakanson AS, Vasan RS, Johnson AD, Iafrati MD, Benjamin EJ.  The Relation of Platelet and Leukocyte Inflammatory Transcripts to Body Mass Index in the Framingham Heart Study.  Circulation. 2010, 3;122(2):119-29.  PMCID: PMC2910759

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