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The major research initiatives in Dr. Freedman’s laboratory emphasize the regulation of pathways contributing to atherothrombotic disease and how these factors contribute to acute coronary syndromes.  Dr. Freedman lab is focused on two research programs; the first is a basic science laboratory that examines the role of immunity, infection, and inflammation on atherothrombotic disease.  The second facility uses high-throughput, nano-chip, proteomic and RNAseq technologies to study gene and protein expression providing translational data for a wide range of projects and has measured gene expression in thousands of clinical and biological samples for dozens of studies.