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2021 RESEARCH

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Top story: UMass Medical School researchers to start trial of Moderna COVID-19 vaccine in teens

Top story: UMass Medical School researchers to start trial of Moderna COVID-19 vaccine in teens

UMass Medical School researchers are about to start enrolling adolescents ages 12 through 17 in a clinical trial to test the COVID-19 mRNA vaccine made by Moderna. (Originally published on Jan. 26, 2021)

Top story: Preventative shot for Lyme disease, developed at UMass Medical School, enters clinical trial

Top story: Preventative shot for Lyme disease, developed at UMass Medical School, enters clinical trial

Lyme PrEP, a seasonal shot to prevent Lyme disease developed by MassBiologics at UMass Medical School, has begun enrolling volunteers to evaluate the safety and pharmacology of the treatment. (Originally published on Fed. 24, 2021)

UMass Chan clinical trial shows antisense oligonucleotide safely suppresses mutant ALS gene in pilot human study

UMass Chan clinical trial shows antisense oligonucleotide safely suppresses mutant ALS gene in pilot human study

Robert H. Brown Jr., DPhil, MD, Jonathan Watts, PhD, and colleagues have shown the ability to suppress mutant forms of an ALS gene in a single-patient pilot study.

Early use of convalescent plasma treatment for COVID-19 helps avoid hospitalization

Early use of convalescent plasma treatment for COVID-19 helps avoid hospitalization

Results of a clinical trial led by Jonathan M. Gerber, MD, suggest that early use of convalescent plasma treatment for COVID-19 helps avoid hospitalization.

Zaida Ramirez-Ortiz awarded Lupus Innovation Award for cell research in lupus

Zaida Ramirez-Ortiz awarded Lupus Innovation Award for cell research in lupus

Zaida Ramirez-Ortiz, PhD’11, received a 2021 Lupus Innovation Award by the Lupus Research Alliance for her work probing an underlying mechanism of lupus.

Moderna COVID-19 booster clinical trial starting at UMass Chan

Moderna COVID-19 booster clinical trial starting at UMass Chan

UMass Chan Medical School researchers are starting a Phase II clinical trial of Moderna COVID-19 mRNA vaccine boosters in adults. The study comes as scientists chase the continuous emergence of new SARS-CoV-2 virus variants. 

Communicating science: Brian Lewis discusses overcoming therapeutic resistance in pancreatic cancer

Communicating science: Brian Lewis discusses overcoming therapeutic resistance in pancreatic cancer

Brian Lewis, PhD, is studying therapeutic resistance in pancreatic cancer cells, hoping to change the grim statistics for patients diagnosed with pancreatic cancer.

William Flavahan receives Distinguished Scientist Award for groundbreaking brain cancer research

William Flavahan receives Distinguished Scientist Award for groundbreaking brain cancer research

William Flavahan, PhD, has received a four-year, $600,000 award from the Sontag Foundation to advance his studies of the genetic processes leading to brain tumors.

Caterina Strambio De Castillia and her team advance efforts to set microscopy data standards

Caterina Strambio De Castillia and her team advance efforts to set microscopy data standards

UMass Chan Medical School researcher and Chan Zuckerberg Initiative Imaging Scientist Caterina Strambio De Castillia, PhD, is the senior author on two papers and a co-author on four more published in the December issue of Nature Methods.

Han lab developing light-activated immune cell therapy for cancers

Han lab developing light-activated immune cell therapy for cancers

Gang Han, PhD, said newly developed nano-optogenetic immunotherapy represents a new generation of personalized cancer treatment, in which precise control of the timing, location and dosage of T cell activation could be tailored to an individual patient.

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