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Comprehensive scientific and clinical solutions to address the critical challenge of drug resistance by prioritizing drug design and therapeutic strategies. 

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  • Medicines Designed to Last

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  • Uncovering Pathways to Resistance in cancer

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  • Chemo Chainsaw

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  • Overcoming Therapeutic Resistance in Pancreatic Cancer

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  • Newest Drugs for the Oldest Parasites

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  • Thwarting Antibiotic Resistance in Psuedonomas Aerginosa

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  • Using Structural Biology to Tackle Antibiotic Resistance

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  • Modifying Bacterial Behavior to Avoid Antibiotic Resistance

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  • How to Discover New Antibiotics by Getting Bacteria to “Talk” to Each Other

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  • Bacteria Infection of Cancer Tumors

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  • Preventing Antibiotic Resistance by Blocking Evolution

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Latest News

Getting Results…
  • UMass Chan BRIDGE Fund commits $2M in six faculty projects

    UMass Chan BRIDGE Fund commits $2M in six faculty projects

    BRIDGE Innovation and Business Development at UMass Chan Medical School has set aside nearly $2 million in funding for six faculty-led research projects that hold promise for translation to clinical application and commercialization.  

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  • With new name, Department of Microbiology focuses on microbial life and its impact on health

    With new name, Department of Microbiology focuses on microbial life and its impact on health

    The UMass Chan Medical School Department of Microbiology and Physiological Systems is now the Department of Microbiology, according to Beth McCormick, PhD.  

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  • UMass Chan scientists show ribosomes play unexpected role in blood vessel formation

    UMass Chan scientists show ribosomes play unexpected role in blood vessel formation

    Research by Andrei Korostelev, PhD, and Anna Loveland, PhD, shows that the ribosome plays an unexpected role in the activation of angiogenin, allowing it to cleave transfer RNA, thereby halting protein production. These findings shed new light on angiogenin functioning and may have important implications for the design of cancer therapeutics and neurodegenerative disease treatments.  

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  • Science for Living: Gut microbiome offers clues to chronic disease

    Science for Living: Gut microbiome offers clues to chronic disease

    Researchers in UMass Chan Medical School’s Center for Microbiome Research are exploring the causal mechanisms by which bacteria in the gut influence chronic illnesses such as Alzheimer’s and Crohn’s disease and in autoimmune disorders and other conditions.

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  • Celia A. Schiffer elected to National Academy of Sciences

    Celia A. Schiffer elected to National Academy of Sciences

    Celia Schiffer, PhD, was elected to the National Academy of Sciences for her distinguished and continuing achievements in original biomedical research.

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  • Faculty shine at Educational Recognition Awards ceremony, Last Lecture

    Faculty shine at Educational Recognition Awards ceremony, Last Lecture

    Faculty members from the three UMass Chan graduate schools were honored at the 2024 Educational Recognition Awards ceremony and Susan Zweizig, MD, delivered the annual honorary Last Lecture, titled “What You Don’t See.”

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  • UMass Chan delivers fitting tribute to young Worcester scholars

    UMass Chan delivers fitting tribute to young Worcester scholars

    UMass Chan presented “scientist-in-training” lab coats to Lake View Elementary School, one of the 11 North Quadrant schools in Worcester that are part of the UMass Chan North Quadrant Support Services Initiative.

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  • Study co-authored by Jonathan Gerber shows COVID-19 vaccines reduce harmful inflammation

    Study co-authored by Jonathan Gerber shows COVID-19 vaccines reduce harmful inflammation

    Vaccination against COVID-19 was linked to reduced inflammation in response to SARS-CoV-2 infection, according to a paper co-authored by UMass Chan Medical School researcher Jonathan M. Gerber, MD.

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  • UMass Chan Medical School launches Partner in Microscopy program with Leica Microsystems

    UMass Chan Medical School launches Partner in Microscopy program with Leica Microsystems

    The UMass Chan Medical School light microscopy core facility, Sanderson Center for Optical Experimentation, announced a new collaboration with Leica Microsystems.

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  • Phillip Zamore, Roger Davis elected to National Academy of Medicine

    Phillip Zamore, Roger Davis elected to National Academy of Medicine

    UMass Chan Medical School scientists Phillip D. Zamore, PhD, and Roger J. Davis, PhD, FRS, were elected to the National Academy of Medicine on Oct. 9 for their distinguished contributions to medicine and health.

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