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Comprehensive scientific and clinical solutions to address the critical challenge of drug resistance by prioritization in drug design and therapeutic strategies.

 

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  • Medicines Designed to Last

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  • Uncovering Pathways to Resistance in cancer

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  • Chemo Chainsaw

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  • Overcoming Therapeutic Resistance in Pancreatic Cancer

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  • Designed Biologics as Antivirals to avoid Drug Resistance

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  • Newest Drugs for the Oldest Parasites

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  • Thwarting Antibiotic Resistance in Psuedonomas Aerginosa

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  • Using Structural Biology to Tackle Antibiotic Resistance

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  • Modifying Bacterial Behavior to Avoid Antibiotic Resistance

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  • How to Discover New Antibiotics by Getting Bacteria to “Talk” to Each Other

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  • How I Stopped Worrying and Learned to Love the Microbiome

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  • Bacteria Infection of Cancer Tumors – The Hidden Passengers we Ignored for too Long

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  • Preventing Antibiotic Resistance by Blocking Evolution

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Latest News

Getting Results…
  • Nanobody treatment developed by MassBiologics shows promise for treating SARS-CoV-2 infection
    Research News

    Nanobody treatment developed by MassBiologics shows promise for treating SARS-CoV-2 infection

    MassBiologics of UMass Chan Medical School develops novel nanobody as inhalable and affordable medicine against SARS-CoV-2 and emerging variants.

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  • Sharon Cantor and Andres Schanzer appointed to endowed chairs
    Community News

    Sharon Cantor and Andres Schanzer appointed to endowed chairs

    The University of Massachusetts Board of Trustees voted to approve one new endowed chair at UMass Chan Medical School and the appointment of two accomplished faculty members to endowed chairs.

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  • Communicating science: Elizabeth Shank works to identify new antibiotics by getting bacteria ‘talking’
    Media, Research News

    Communicating science: Elizabeth Shank works to identify new antibiotics by getting bacteria ‘talking’

    In her lab, Elizabeth Shank, PhD, interprets the chemical language of bacteria with the goal of harnessing its power to potentially developing new antibiotics.

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  • PhD student Megan Honeywell receives prestigious Ruth L. Kirschstein Predoctoral award
    Research News

    PhD student Megan Honeywell receives prestigious Ruth L. Kirschstein Predoctoral award

    In her preliminary studies, PhD student Megan Honeywell has found that cells can trigger a cell death even when they do not have the p53 protein, the so-called “guardian of the genome.”

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  • Roberto Caricchio, Michelle Kelliher and Celia Schiffer appointed to endowed chairs
    Community News, Media

    Robert Caricchio, Michelle Kelliher and Celia Schiffer appointed to endowed chairs

    UMass Chan faculty in rheumatology, biochemistry & molecular biotechnology and cancer biology are being supported by endowments.

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  • New research shows effectiveness of COVID-19 convalescent plasma in reducing hospitalization
    Research News

    New research shows effectiveness of COVID-19 convalescent plasma in reducing hospitalization

    A large, double-blind, randomized controlled trial found that outpatients who received convalescent plasma within nine days of onset of COVID-19 symptoms were significantly less likely to be hospitalized than those who received placebo control plasma.

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  • Communicating science: Read Pukkila-Worley studies antibiotic resistance in bacterial infection
    Media, Research News

    Communicating science: Read Pukkila-Worley studies antibiotic resistance in bacterial infection

    Read Pukkila-Worley, MD, is a physician-scientist researching how bacteria cause disease and how the immune system detects infection.

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  • Communicating science: Raffi Van Aroian studies parasites in humans
    Media, Research News

    Communicating science: Raffi Van Aroian studies parasites in humans

    Raffi Van Aroian, PhD, studies intestinal parasitic nematodes, or worms, which can seriously impact children. To combat drug resistance, he and colleague Gary R. Ostroff, PhD, are working on a new type of treatment.

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  • UMass Chan researcher explains convalescent plasma’s potential as COVID-19 treatment
    Media, Research News

    UMass Chan researcher explains convalescent plasma’s potential as COVID-19 treatment

    Jonathan Gerber, MD, discusses a therapy that has been around for at least a century and how it has helped in the COVID-19 pandemic.

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  • Communicating science: Yang Wang discusses drug resistance in COVID-19
    Media, Research News

    Communicating science: Yang Wang discusses drug resistance in COVID-19

    Yang Wang, MD, PhD, leads a team of scientists working to discover and develop antibody-based medicines for infectious diseases and understand drug resistance in those medicines.

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