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Lyne Khair, PhD

Research Focus - Novel Epigenetic-based Approaches for the Development of Strategies to Reduce the Incidence and Severity of Breast Cancer

  • Understanding the modulation of cancer immunosurveillance in breast tumors
  • Studying the impact of physical activity on the epigenetic regulation of hematopoietic stem cells and the subsequent effect on immune cell infiltration in breast tumors
  • Investigating the cross-talk between the tumor microenvironment and hematopoietic stem cells
  • Understanding the novel role of physical activity in the reduction of the incidence and severity of breast cancer

Representative Publication

Tie G, Yan J, Khair L, et al. Hypercholesterolemia increases colorectal cancer incidence by reducing production of NKT and γδ T cells from hematopoietic stem cells. Cancer Res. 2017;77(9):2351-2362.

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